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Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan
Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
Center of Anti-Aging and Health Consultation, National Taiwan University Hospital, Taipei, Taiwan
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.5) Subclinical hypothyroidism 8 (17.8) 19 (13.4) Euthyroid 25 (55.6) 63 (44.4) a Comparison between female and male; bold values denote statistical significance at the P < 0.05 level; b Cannot be identified from the chart review
Department of Women’s and Children’s Health, Pediatric Endocrinology Unit, Padua University Hospital, Padua, Italy
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in euthyroid patients (euthyroid GO) ( 2 ). The most common clinical manifestations of TED are proptosis, eyelid retraction, conjunctivitis, extraocular muscle hypertrophy with consequent reduction of ocular motility, diplopia and, in the most
Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Endocrinology Division, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA
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when the disease is inactive and euthyroidism has been achieved and maintained. Key Point 7.3.2.1: The specific surgical approach should be tailored to the indication (DON, proptosis), type of orbitopathy (muscle or fat predominant congestive
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Public Health Unit, ACES Baixo Mondego, Coimbra, Portugal
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Department of Endocrinology, Hospital University Centre of São João, Porto, Portugal
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Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto, Porto, Portugal
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(ETA) recommends Se in patients with mild Graves’ orbitopathy (GO) ( 24 , 25 ). This recommendation is based on a 2011 European randomised, controlled trial ( 26 ), which evaluated the effect of 200 μg/day sodium selenite for 6 months in euthyroid
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fibrillation had been diagnosed 8 months earlier. He had become euthyroid on methimazole 10 mg per day; additional medications were propranolol, apixaban, and ramipril for pre-existing essential hypertension. He recalled that eyelid swelling, double vision, and
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Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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euthyroid function ( P = 0.844). The disease duration of TED patients in the GC-effective group was significantly shorter than that in the GC-ineffective group (5.0 (2.0, 8.5) vs 7.0 (5.0, 12.0) months, P = 0.017) ( Fig. 3A ). As for serological lipid
Endocrinology Unit, Graves’ Orbitopathy Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Ophthalmology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Department of Specialistic Surgical Sciences, Otolaryngology and Head and Neck Surgery, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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National Institute of Molecular Genetics (INGM) “Romeo and Enrica Invernizzi”, Milan, Italy
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achieved stable euthyroidism on levothyroxine replacement therapy. After only one dose of RTX treatment, TED remained persistently inactive and stable (CAS 0; proptosis 25/23.5 mm, constant diplopia), with further improvement of lid retraction (7/9 mm) up
Ilisimatusarfik, University of Greenland, Nuuk, Greenland
National Board of Health, Nuuk, Greenland
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Ilisimatusarfik, University of Greenland, Nuuk, Greenland
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Queen Ingrid’s Health Care Centre, Nuuk, Greenland
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Ilisimatusarfik, University of Greenland, Nuuk, Greenland
Department of Internal Medicine, Queen Ingrid’s Hospital, Nuuk, Greenland
Department of Geriatric Medicine, Aalborg University Hospital, Aalborg, Denmark
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Andersen S . Intake of seaweed as part of a single sushi meal, iodine excretion and thyroid function in euthyroid subjects: a randomized dinner study . Journal of Endocrinological Investigation 2020 43 431 – 438 . ( https://doi.org/10.1007/s40618
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their positivity in euthyroid patients may be the risk factor for future thyroid disorders ( 15 ). They may be involved in autoimmune thyroid cell death via antibody-dependent cytotoxicity cells (ADCC) and C3 complement-mediated cytotoxicity ( 16
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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.4/0.2/0.8 PTU only 1 (3.3%) 0 1 (3.3%) 1/1/1 Levothyroxine and tapzole 12 (40%) 12 (40%) 14 (46.7%) 0.9/1/0.8 Levothyroxine and PTU 4 (13.3%) 1 (3.3%) 4 (13.3%) 0.4/0.4/1 Euthyroid ( n , %) 23 (76.7%) 25 (83