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resistance (IR) ( 2 , 3 ). In a meta-analysis pooling studies from the period, 2000 to 2014, no increased risk of GDM was reported in euthyroid women with TAI (relative risk (RR) 1.07 (95% CI, 0.96–1.19)) ( 2 ). However, in original studies published since
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language acquisition, i.e. the MB-CDI parent reports. Only one study, by Henrichs et al. ( 48 ), has previously employed this instrument for investigating the association between thyroid function in euthyroid treatment-naive women and productive language
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/m–L after June 2014. LT4 treatment was prescribed according to the 2014 ETA guidelines recommendations ( 2 ). The thyroid status at LT4 initiation was defined as follows: euthyroidism (normal range TSH and normal trimester-specific range FT4); SCH (TSH
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pregnancy in euthyroid women . Best Practice and Research. Clinical Endocrinology and Metabolism 2023 37 101632 . ( https://doi.org/10.1016/j.beem.2022.101632 ) 21 Benson AE Shatzel JJ Ryan KS Hedges MA Martens K Aslan JE & Lo JO . The
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Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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). However, the scientific focus on pregnant women has moved beyond overt hypothyroidism toward smaller abnormalities in maternal thyroid function. Furthermore, the role of thyroid autoimmunity per se is considered, and treatment of euthyroid pregnant women
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male foetus (MF) only ( 8 ). In another study, early maternal FT4 levels in euthyroid women were inversely associated with birth weight with a stronger association in case of an MF ( 7 ). Finally, among euthyroid women with TAI, after adjustment for
Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China
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Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China
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Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China
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of labor were examined. Compared with euthyroid, subclinical hypothyroidism in the third trimester exhibited a significantly prolonged length of the first stage of labor after adjustment for potential confounders (β = 0.30 h, 95% CI: 0.001, 0.56, P
ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal
Hospital de Braga, Braga, Portugal
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ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal
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Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands
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contradictory. Gowachirapant et al. and Zhou et al. ( 29 , 30 ) suggested that iodine supplementation (200 µg/day) in mildly iodine-deficient pregnant women had no benefit on newborn outcomes. A recent meta-analysis in euthyroid women showed that the pooled
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Department of Medicine, Autonomous University of Barcelona, Badalona, Spain
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Health Department, Centre d’Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Generalitat de Catalunya, Badalona, Spain
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Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain
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percentile of the reference interval for the euthyroid population, was regarded as TPO-negative. For anti-thyroglobulin antibodies (aTgAb) (Architect Ref. 2K46, Abbott Diagnostic Division), the sensitivity of the assay was 0.16 IU/mL, LoQ was <1.0 IU/mL, and
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The Rappaport Faculty of Medicine, Technion, Institute of Technology, Haifa, Israel
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autoantibodies. He had non-autoimmune euthyroid persistent hyperthyrotropinemia and LT4 supplement therapy was initiated only at the age of 2 years. Patient 3 was born to first cousin parents. His mother had non-autoimmune hypothyroidism and his older sister had