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-operation and Development (OECD) guidelines, guidelines concerning good laboratory practice (GLP), and other applications ( 45 ). Experiments were performed in accordance with well-established procedures in regulatory experimental toxicology and were deeply
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disorders . Lancet Diabetes and Endocrinology 2015 3 286 – 295 . ( https://doi.org/10.1016/S2213-8587(1470225-6 ) 14 Bednarczuk T Brix TH Schima W Zettinig G & Kahaly GJ . 2021 European Thyroid Association guidelines for the management of
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review and meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines ( 17 ). We searched exhaustively different databases like PubMed/Medline, Google Scholar, Science Direct, Embase, and unpublished
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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Center for Interdisciplinary Research on Medicines (C.I.R.M.), University of Liege (ULiège), CHU (B35), Liege, Belgium
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-lapse was selected because some of the EDCs analyzed have a maximum half-life of about 5 years. All patients with TC were submitted to surgery (total thyroidectomy or lobectomy), radioiodine ablation, and LT4 treatment according to international guidelines
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea
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Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea
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Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea
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Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea
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excluding two children with congenital hypothyroidism, 228 children (123 boys) were included in this study. This study was performed in accordance with the guidelines of Helsinki Declaration. The study was approved by the Institutional Review Board of Seoul
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China
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Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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.4%, respectively; the intra-assay CVs were 2.7%, 1.4%, and 2.3%, respectively. Iodine group Iodine status was based on the UIC and divided into four groups as established by guidelines from the World Health Organization: deficient iodine (DI UIC, <100 µg