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Eduardo Crespo Vallejo Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Antonio Hermosin Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Manuel Gargallo Endocrinology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Álvaro Villalba Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Eduardo Daguer Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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José Flores Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Javier Periañez Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Joaquim Amorín Interventional Radiology, Hospital Universitario Fundacion Jiménez Diaz, Madrid, Spain

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Ernesto Santos Interventional Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

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) subclinical or symptomatic hyperthyroidism. Patients with the following were excluded: (i) coagulation dysfunction, (ii) retrosternal growth, and (iii) pregnant. The size of the nodule to be ablated was never an exclusion criterion if the entire nodule was

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Tomohiro Kikuchi Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan

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Shouhei Hanaoka Department of Radiology, The University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Takahiro Nakao Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Yukihiro Nomura Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan

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Takeharu Yoshikawa Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Ashraful Alam Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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Harushi Mori Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan

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Naoto Hayashi Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan

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. The PET images were acquired with the following parameters: FOV, 700 mm; matrix size, 128 × 128; voxel size, 5.47 × 5.47 × 3.25 mm. Hypothyroidism and hyperthyroidism, defined as elevated and decreased thyroid-stimulating hormone (TSH) levels

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Aglaia Kyrilli Department of Endocrinology, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik 808, Brussels, Belgium

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Nunzia Tacelli Department of Radiology, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik 808, Brussels, Belgium

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Lucia Russo Department of Medicine, DIMED, Internal Medicine 3, University of Padua, Via Giustiniani 2, 35128, Padova, Italy

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Laetitia Lebrun Department of Pathology, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik 808, Brussels, Belgium

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Isabelle Salmon Department of Pathology, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik 808, Brussels, Belgium

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Gilles Russ Thyroid and Endocrine Tumors, Institute of Endocrinology, Pitié Salpêtrière Hospital, Pierre et Marie Curie University, Paris, France

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Rodrigo Moreno-Reyes Department of Nuclear Medicine, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik, Brussels, Belgium

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Bernard Corvilain Department of Endocrinology, Hôpital Universitaire de Bruxelles (H.U.B.)– Hôpital Erasme, Université Libre de Bruxelles (ULB), Route de Lennik 808, Brussels, Belgium

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crucial determinants of serum TSH ( 10 , 11 , 12 , 13 , 14 ). When scintigraphy is routinely performed in thyroid nodule workup, it allows detection of AFTN at early stages before progression to subclinical and/or overt hyperthyroidism. Ultrasound

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Muhammad Fahad Arshad Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK

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Amardass Dhami Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

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Gillian Quarrell Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

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Saba Prakash Balasubramanian Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK

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cancer, hyperthyroidism (such as Graves’ disease), and nodular disease. The type of surgery was recorded as total thyroidectomy (TT) or completion thyroidectomy (CT), with or without central node dissection (CND), while the histological diagnosis was

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Pi-Ling Chiang Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Sheng-Dean Luo Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yen-Hsiang Chang Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Chen-Kai Chou Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Shun-Yu Chi Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Yi-Fan Chen Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan

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Wei-Che Lin Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan

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2019 and September 2021. All nodules were submitted either to repeat FNAC or to CNB. Exclusion criteria were patients with (i) cardiac pacemaker, (ii) pregnancy, (iii) autoimmune thyroiditis, (iv) hyperthyroidism or subclinical hyperthyroidism, (v

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Cosimo Durante Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Agnieszka Czarniecka M. Sklodowska-Curie National Research, Institute of Oncology Gliwice Branch, Gliwice, Poland

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Ralf Paschke Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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Gilles Russ Thyroid and Endocrine Tumors Department, Pitié-Salpêtrière Hospital, Sorbonne University GRC N°16, Paris, France

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Fernando Schmitt Faculty of Medicine of University of Porto, CINTESIS@RISE and Institute of Molecular Pathology and Immunology, University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Institute of Investigation and Innovation in Health (I3S), Faculty of Medicine of the University of Porto, Porto, Portugal

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Tamas Solymosi Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary

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Enrico Papini Department of Endocrine and Metabolic Diseases, Regina Apostolorum Hospital, Albano, Rome, Italy

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conditions (for details see the guideline text). 2) If the FT4 is normal, FT3 should be measured. 3) Based on the clinical context TSH receptor antibody determination may be considered to define the etiology of hyperthyroidism. 4) Consider TPOAb determination

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Tamas Solymosi Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary
Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Laszlo Hegedűs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Steen J Bonnema Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Andrea Frasoldati Endocrinology Unit of Arcispedale S Maria Nuova, Reggio Emilia, Italy

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Laszlo Jambor Department of Radiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Zsolt Karanyi Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Gabor L Kovacs 1st Department of Medicine, Flohr Ferenc Hospital, Kistarcsa, Hungary

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Enrico Papini Regina Apostolorum Hospital in Albano, Rome, Italy

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Karoly Rucz 1st Department of Medicine, University of Pecs, Pecs, Hungary

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Gilles Russ Unité Thyroïde et Tumeurs Endocrines – Pr Leenhardt Hôpital La Pitie Salpetriere, Sorbonne Université, Paris, France

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Endre V Nagy Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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in 32 patients, and Bethesda VI in 28 patients), symptoms and/or signs of compression caused by the goiter in 35 cases, an autonomously functioning nodule causing hyperthyroidism in 5 patients, and patients’ wish in 4 cases. Final diagnoses were, in

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