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Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
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. 2009 Jan 25 ; 10 : 5 http://dx.doi.org/10.1186/1745-6215-10-5 . 17 Amouzegar A , Delshad H , Mehran L , Tohidi M , Khafaji F , Azizi F . Reference limit of thyrotropin (TSH) and free thyroxine (FT4) in thyroperoxidase positive
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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-Ab, anti-thyroid peroxidase antibodies. TSH and free thyroxine (fT4) have a complex, nonlinear relationship, and small variations in fT4 circulating levels result in substantial changes in serum TSH ( 5 ). For this reason, the TSH is the most
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
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Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
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Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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brain damage resulting in mental retardation and impaired motor function ( 1 , 2 , 3 , 4 ). Radioimmunoassays, developed in the 1970s, made measurement of blood thyroxine (T4) concentrations in the nanomoles per liter range possible, allowing early
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Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
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Introduction The thyroid hormone affects almost every organ system in the body, including the cardiovascular, central nervous, skeletal, and gastrointestinal systems and metabolism. Tetraiodothyronine or thyroxine (T 4 ) and triiodothyronine
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Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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pregnancy. The median values are represented as a horizontal line. The edges represent respectively the 25th and the 75th centile of the cohort. Vertical lines represent the range. FT4, free thyroxine; LT4, levothyroxine; DBS, dried blood spot; TSH, thyroid
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Data and Data Support, Region Zealand, Sorø, Denmark
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Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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the reference range of 0.3–4.0 mIU/L and total plasma thyroxine (TT4) below the reference range of 60–130 nmol/L) or mild (plasma TSH above the reference range, and plasma TT4 within the reference range). Exclusion criteria were pregnancy or planned
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thyroxine (T4). Deiodination of the outer ring generates the active thyroid hormone triiodothyronine (T3), whereas that of the inner ring converts T4 to reverse T3 (rT3), and T3 to 3,3’-diiodo- l -thyronine (T2), which are both biologically inactive
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Institute of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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.9 ± 17.6 83.1 ± 18.7 0.219 Statistically significant difference ( P < 0.05) is highlighted in bold. FT3I, free T3 index; FT4, free thyroxine; LT4, levothyroxine; T3, triiodothyronine; TSH, thyrotropin; TPOAb, thyroid peroxidase
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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biochemical evaluation with the measurement of thyroid-stimulating hormone (TSH). Results revealed an elevated plasma level of TSH (>100 mIU/L). Simultaneous measurements of total thyroxine (T4) as well as total triiodothyronine (T3) showed that the plasma
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,000 to 1 in 100,000 ( 1 , 2 ). The signs and symptoms associated with CeH are generally milder, compared to primary hypothyroidism, often leading to a delay in diagnosis. The typical biochemical picture observed in CeH is of a low free thyroxine (FT4