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without this leading to a significant lowering of thyroid cancer mortality ( 11 , 12 , 13 ). There is a pronounced need for more cost-effective, risk-adapted approaches to the management of this highly prevalent condition, taking the wishes of the
Medical School, University of Milan, Milan, Italy
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Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
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Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
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Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Medical School, European University of Cyprus, Nicosia, Cyprus
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altered clinical management. Indeed, a national screening programme in South Korea did not show any reduction in mortality despite a substantial rise in thyroidectomies and differentiated thyroid carcinoma diagnoses ( 7 ). Diagnostic ultrasound
University of Sheffield, Sheffield, UK
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University of Sheffield, Sheffield, UK
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identification of parathyroid glands at surgery, reoperation after bleeding, Graves’ disease, and large thyroid glands ( 9 ). Long-term hypoparathyroidism is associated with significant morbidity and mortality ( 10 , 11 ). PoSH patients are at increased risk of