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Ying Sun Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Di Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Lei Zhao Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China

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Xiaoguang Shi Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Yongze Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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reference limit (0.27–4.20 mIU/L). The normal reference ranges for thyroid function were, TSH, 0.27–4.2 mIU/L; fT4, 12.0–22.0 pmol/L; fT3, 3.1–6.8 pmol/L; TPOAb, <34.0 IU/mL; and TgAb, <115.0 IU/mL, as reported by the test kit manufacturers. The UIC was

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Yun Jeong Lee Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Hun Choi Department of Radiology, Seoul National University Hospital, Seoul, Korea

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Youn-Hee Lim Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea

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Bung-Nyun Kim Division of Children and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea

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Johanna Inhyang Kim Department of Psychiatry, Hanyang University Medical Center, Seoul, Republic of Korea

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Yun-Chul Hong Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Joo Park Department of Internal medicine, Seoul National University Hospital, Seoul, Republic of Korea
Department of Internal medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Choong Ho Shin Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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Sun Wook Cho Department of Internal medicine, Seoul National University Hospital, Seoul, Republic of Korea
Department of Internal medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Ah Lee Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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thyroid function Free thyroxine (FT4) and thyroid stimulating hormone (TSH) were measured using a chemiluminescent microparticle immune assay on an ARCHITECT i2000 System (Abbott Korea). The reference range was defined as 0.70–1.48 ng/dL (9.01–19.05 pmol

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