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Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan
Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
Center of Anti-Aging and Health Consultation, National Taiwan University Hospital, Taipei, Taiwan
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was diagnosed, the logistic regression model showed a positive correlation between age at diagnosis and the likelihood of developing overt thyroid dysfunction. For every year older patients diagnosed with APS III, there was a 3.6% increase in the risk
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the utilization of CAS in conjunction with orbital MRI. Meanwhile, 31.5% (91/289) of doctors relied solely on CAS. It is worth noting that this method carries inherent risks, as CAS provides a close but not entire reflection of disease progression
Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Endocrinology Division, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA
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.2.2: RT should be used cautiously in diabetic patients to avoid possible retinopathy. It is relatively contraindicated for those younger than 35 years of age to avoid a theoretical lifetime risk of tumors developing in the radiation field. Key Point
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Public Health Unit, ACES Baixo Mondego, Coimbra, Portugal
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Department of Endocrinology, Hospital University Centre of São João, Porto, Portugal
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Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto, Porto, Portugal
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twins, compared with only 3% in dizygotic twins, suggesting that genetic factors contribute to the pathogenesis. AITD can place patients at a higher risk for relevant conditions, such as cardiovascular diseases, osteoporosis, and infertility ( 4
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negative impact on the quality of life of affected individuals ( 2 ) because of its disfiguring (exophthalmos) and dysfunctional (diplopia) features and can only partially be prevented by intervening to change modifiable risk factors ( 3 ). In the large
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Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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clinically simple and readily possible ( 10 ). Lipid metabolism plays a crucial role in maintaining the normal life activities of the body. Recent studies have suggested that hypercholesterolemia may be a new risk factor for developing TED ( 6 , 11 , 12
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
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gain, depression and cardiovascular events ( 3 ). Typically, AIT starts from the loss of immune tolerance toward thyroid-specific self-antigens due to genetic predisposition, environmental factors, gut microbiome, and immunity. However, the risk factors
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their positivity in euthyroid patients may be the risk factor for future thyroid disorders ( 15 ). They may be involved in autoimmune thyroid cell death via antibody-dependent cytotoxicity cells (ADCC) and C3 complement-mediated cytotoxicity ( 16
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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should be monitored in practice. The frequency of measuring BMD in our study (12-week interval) may have little long-term significance. However, the purpose of reassessing BMD was not to assess fracture risk, but to assess early BMD loss and its
Endocrinology Unit, Graves’ Orbitopathy Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Ophthalmology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Department of Specialistic Surgical Sciences, Otolaryngology and Head and Neck Surgery, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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National Institute of Molecular Genetics (INGM) “Romeo and Enrica Invernizzi”, Milan, Italy
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://doi.org/10.1089/thy.2018.0232 ) 6 Ueland GÅ Ueland HO Stokland AM Bhan A Schønberg A Sollid ST Morgas DE Holmøy T Lima K Methlie P , et al. Prevalence, risk factors, clinical and biochemical characteristics of alemtuzumab-induced Graves