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Christiaan F Mooij
Christiaan F Mooij
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
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Timothy D Cheetham
Timothy D Cheetham
Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK
Department of Pediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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Department of Pediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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Frederik A Verburg
Frederik A Verburg
Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands
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Anja Eckstein
Anja Eckstein
Department of Ophthalmology, University Duisburg Essen, Essen, Germany
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Simon H Pearce
Simon H Pearce
Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK
Endocrine Unit, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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Endocrine Unit, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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Juliane Léger
Juliane Léger
Department of Pediatric Endocrinology and Diabetes, Reference Center for Rare Endocrine Growth and Development Diseases, Endo-ERN HCP, Assistance Publique-Hôpitaux de Paris, Robert Debré University Hospital, University of Paris, NeuroDiderot Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France
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A S Paul van Trotsenburg
A S Paul van Trotsenburg
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
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Introduction Purpose and scope of guideline Hyperthyroidism caused by Graves’ disease (GD) is a relatively rare disease in children. Although treatment options are the same as in adults – antithyroid drugs (ATD), radioactive iodine (RAI
Marise Codeco de Andrade Barreto
Marise Codeco de Andrade Barreto
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Natalia Treistman
Natalia Treistman
Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Lara Bessa Campelo Pinheiro Cavalcante
Lara Bessa Campelo Pinheiro Cavalcante
Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Daniel Bulzico
Daniel Bulzico
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
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Fernanda Accioly de Andrade
Fernanda Accioly de Andrade
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
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Rossana Corbo
Rossana Corbo
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
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Paulo Alonso Garcia Alves Junior
Paulo Alonso Garcia Alves Junior
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Fernanda Vaisman
Fernanda Vaisman
Department of Oncologic Endocrinology, Instituto Nacional de Câncer – INCA, Rio de Janeiro, RJ, Brazil
Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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Department of Endocrinology, Universidade Federal do Rio de Janeiro – UFRJ, Faculdade de Medicina, Rio de Janeiro, RJ, Brazil
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to treatment with iodine-131 (radioiodine (RAI)). However, controversy exists regarding the gonadotoxic effects of RAI in DTC survivors, which may include menstrual irregularity, miscarriage, premature ovarian failure, impaired fertility, and genetic
Andrew J Bauer
Andrew J Bauer
Division of Endocrinology and Diabetes, The Children’s Hospital of Philadelphia, Department of Pediatrics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Jonathan D Wasserman
Jonathan D Wasserman
Division of Endocrinology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
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Steven G Waguespack
Steven G Waguespack
Department of Endocrine Neoplasia and Hormonal Disorders and Department of Pediatrics-Patient Care, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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human thyroid-stimulating hormone for radioactive iodine (RAI) imaging and therapy, reducing the minimum time on a low-iodine diet to 4 days prior to 131 I, and modifying the recommendation for lifelong surveillance from the 2015 ATA Pediatric
Chantal A Lebbink
Chantal A Lebbink
Wilhelmina Children’s Hospital and Princess Máxima Center, Utrecht, The Netherlands
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Thera P Links
Thera P Links
Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Agnieszka Czarniecka
Agnieszka Czarniecka
The Oncologic and Reconstructive Surgery Clinic, M. Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland
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Renuka P Dias
Renuka P Dias
Department of Paediatric Endocrinology and Diabetes, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom
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Rossella Elisei
Rossella Elisei
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Louise Izatt
Louise Izatt
Department of Clinical Genetics, Guy's and St Thomas’ NHS Foundation Trust, London, United Kingdom
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Heiko Krude
Heiko Krude
Institute of Experimental Pediatric Endocrinology, Charité - Universitätsmedizin, Berlin, Germany
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Kerstin Lorenz
Kerstin Lorenz
Department of Visceral, Vascular and Endocrine Surgery, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
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Markus Luster
Markus Luster
Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany
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Kate Newbold
Kate Newbold
Thyroid Therapy Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom
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Arnoldo Piccardo
Arnoldo Piccardo
Department of Nuclear Medicine, EO Ospedali Galliera, Genoa, Italy
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Manuel Sobrinho-Simões
Manuel Sobrinho-Simões
University Hospital of São João, Medical Faculty and Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
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Toru Takano
Toru Takano
Thyroid Center, Rinku General Medical Center, Osaka, Japan
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A S Paul van Trotsenburg
A S Paul van Trotsenburg
Department of Pediatric Endocrinology, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands
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Frederik A Verburg
Frederik A Verburg
Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
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Hanneke M van Santen
Hanneke M van Santen
Wilhelmina Children’s Hospital and Princess Máxima Center, Utrecht, The Netherlands
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TSH levels after rhTSH stimulation of >50mIU. No significant side effects were reported. No studies reported on iodine uptake after rhTSH injection. ⊕⊕⊖⊖ 16. What is the difference in outcome in children with measurable but not rising Tg after
Julia Ramalho Amalio da Silva Breder
Julia Ramalho Amalio da Silva Breder
Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Paulo Alonso Garcia Alves
Paulo Alonso Garcia Alves
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Mario Lucio Araújo
Mario Lucio Araújo
Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Barbara Pires
Barbara Pires
Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Priscila Valverde
Priscila Valverde
Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Daniel Alves Bulzico
Daniel Alves Bulzico
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Fernanda Andrade Accioly
Fernanda Andrade Accioly
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Rossana Corbo
Rossana Corbo
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Mario Vaisman
Mario Vaisman
Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Fernanda Vaisman
Fernanda Vaisman
Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
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dissection is not performed routinely and is only based on clinical or radiological suspicion of lymph node involvement. Most patients in our study received a therapeutic dose of radioactive iodine (RAI) after surgery, followed by suppressive therapy with
Julia A Baran
Julia A Baran
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Mya Bojarsky
Mya Bojarsky
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Stephen Halada
Stephen Halada
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Julio C Ricarte-Filho
Julio C Ricarte-Filho
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Amber Isaza
Amber Isaza
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Aime T Franco
Aime T Franco
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Lea F Surrey
Lea F Surrey
Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Tricia Bhatti
Tricia Bhatti
Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Zubair Baloch
Zubair Baloch
Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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N Scott Adzick
N Scott Adzick
Department of Surgery, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Sogol Mostoufi-Moab
Sogol Mostoufi-Moab
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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Ken Kazahaya
Ken Kazahaya
Division of Pediatric Otolaryngology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Andrew J Bauer
Andrew J Bauer
Division of Endocrinology and Diabetes, The Thyroid Center, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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) staging, distant metastasis (M) staging, ATA risk status, radioactive iodine (RAI) therapy, lymphatic invasion, and response to therapy at 1 year post initial treatment. Genetic alterations were categorized by driver. ATA, American Thyroid Association
