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endocrine effect on the production of thyroid hormones themselves. The most prominent sign of moderate to severe iodine deficiency in a population is a high prevalence of enlarged thyroid glands – previously known as ‘endemic goiter’. In the early 20th
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Internal Medicine, Copenhagen University Hospital – Herlev and Gentofte, Copenhagen, Denmark
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Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Denmark, ID was observed in young men in 1969 ( 3 ). Therefore, in the 1970s, a survey was initiated which found a low prevalence of goiter in school-age children (unpublished data), and thus it was concluded that the Danish population was not iodine
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China
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Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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hypothyroidism. In mild to moderate iodine deficiency, increased thyroid activity can compensate for iodine deficiency in most patients and maintain normal thyroid function. However, chronic thyroid stimulation can lead to increased prevalence of nodular goiter