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M Kim HI Ha J Jeon MJ Kim WG Lim DJ Kim TY Chung JH Shong YK Kim TH Tumor volume doubling time in active surveillance of papillary thyroid microcarcinoma: a multicenter cohort study in Korea . Thyroid 2021 31 1494 – 1501 . ( https
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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features (EU-TIRADS Class 5) ( 2 ). On the other hand, in the ETA GLs for the use of minimally invasive techniques in malignant lesions, RFA has been recommended as therapeutic alternative for the treatment of papillary microcarcinomas and as palliative
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of incidental papillary thyroid microcarcinoma (PTmC) in the background. The presence of incidental PTmC was considered under ‘benign’ on resection as this area may not have been sampled during the FNA procedure. Molecular analysis, if performed, was
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Journal of Clinical Investigation 2009 39 699 – 706 . ( https://doi.org/10.1111/j.1365-2362.2009.02162.x ) 3 Leboulleux S Tuttle RM Pacini F & Schlumberger M . Papillary thyroid microcarcinoma: time to shift from surgery to active surveillance
Medical School, University of Milan, Milan, Italy
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Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
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Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
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Department of Diabetes, Endocrinology & Obesity Medicine, Salford Royal NHS Foundation & University Teaching Trust, Salford, UK
Medical School, European University of Cyprus, Nicosia, Cyprus
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papillary microcarcinoma while the remainder were classic papillary thyroid carcinomas (PTC). An additional three cases (in two patients) of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) were identified; nevertheless
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in unselected thyroid nodule populations generally ranges from 1 to 5%, with variation related to selection criteria and the population under evaluation, for example, whether papillary micro-carcinomas are included or not ( 2 ). Thus, most lesions are
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follicular variant papillary thyroid carcinoma (FvPTC), 29 classical PTC, and 3 tall cell variant PTC. When data were grouped based on the Bethesda classification, 56% of the nodules that underwent biopsy were assigned an indeterminate diagnosis, that is
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gene fusion, which was adjacent to a 32 mm AFTN, both located in the left lobe, in a patient with normal TSH. In four patients undergoing total thyroidectomy an incidental papillary thyroid microcarcinoma (PTMC) was identified outside of the AFTN: in
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan
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) follicular neoplasm, and (vi) malignancy discovered at the second diagnosis. A total of four thyroid nodules were excluded, three of which were determined as follicular neoplasm (Bethesda IV) upon repeat FNAC and one was determined to be papillary