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Rui Guo
Rui Guo
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Bowen Zheng
Bowen Zheng
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Tao Wu
Tao Wu
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Yufan Lian
Yufan Lian
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Tinghui Yin
Tinghui Yin
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Yuting He
Yuting He
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Jingya Qin
Jingya Qin
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Zhicheng Yao
Zhicheng Yao
Department of General Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Wen Xu
Wen Xu
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Jie Ren
Jie Ren
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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that the symptom scores ranged from 0 to 5. RFA procedure When we ablated multiple nodules, to avoid causing serious damage to the recurrent laryngeal nerves, all the dominant nodules in the ipsilateral thyroid lobe were ablated first, starting
Alessia Cozzolino
Alessia Cozzolino
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Tiziana Filardi
Tiziana Filardi
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Ilaria Simonelli
Ilaria Simonelli
Service of Medical Statistics and Information Technology, Fatebenefratelli Foundation for Health Research and Education, Rome, Italy
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Giorgio Grani
Giorgio Grani
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Camilla Virili
Camilla Virili
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Ilaria Stramazzo
Ilaria Stramazzo
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Maria Giulia Santaguida
Maria Giulia Santaguida
Endocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy
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Pietro Locantore
Pietro Locantore
Endocrinology Unit, Fondazione Policlinico Universitario Agostino Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Massimo Maurici
Massimo Maurici
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
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Daniele Gianfrilli
Daniele Gianfrilli
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Andrea M Isidori
Andrea M Isidori
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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Cosimo Durante
Cosimo Durante
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Carlotta Pozza
Carlotta Pozza
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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on behalf of TALENT Group
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age, which is defined as the period between the end of puberty and the achievement of peak bone mass, in an age range between 12 and 21 years ( 8 ). Therefore, the current meta-analysis aimed to bridge this gap by addressing the following issue: which
Laura Fugazzola
Laura Fugazzola
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Maurilio Deandrea
Maurilio Deandrea
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Stefano Borgato
Stefano Borgato
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Marco Dell’Acqua
Marco Dell’Acqua
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Francesca Retta
Francesca Retta
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Alberto Mormile
Alberto Mormile
Endocrinology, Diabetes and Metabolism Department and Center for Thyroid Diseases, Ordine Mauriziano Hospital, Turin, Italy
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Chiara Carzaniga
Chiara Carzaniga
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Giacomo Gazzano
Giacomo Gazzano
Pathology Unit, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Gabriele Pogliaghi
Gabriele Pogliaghi
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Marina Muzza
Marina Muzza
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
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Luca Persani
Luca Persani
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Introduction Radiofrequency ablation (RFA) is an effective treatment for thyroid nodules, with a mean volume reduction ranging 50–90% at 1-year follow-up ( 1 ). As a general rule, the smaller the treated nodule the higher the volume reduction
Rachelle P Mendoza
Rachelle P Mendoza
Department of Pathology, University of Rochester Medical Center, Rochester, New York, USA
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Richard Cody Simon
Richard Cody Simon
Department of Pathology, University of Chicago, Chicago, Illinois, USA
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Nicole A Cipriani
Nicole A Cipriani
Department of Pathology, University of Chicago, Chicago, Illinois, USA
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Tatjana Antic
Tatjana Antic
Department of Pathology, University of Chicago, Chicago, Illinois, USA
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thyroid nodules. Clinical practices have ranged from ultrasound monitoring to repeat FNA. Flanagan et al. studied 70 patients with two or more repeat FNA after an initial benign result and then subsequently underwent surgical management ( 5 ). The repeat
Pi-Ling Chiang
Pi-Ling Chiang
Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Sheng-Dean Luo
Sheng-Dean Luo
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Yen-Hsiang Chang
Yen-Hsiang Chang
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Chen-Kai Chou
Chen-Kai Chou
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Shun-Yu Chi
Shun-Yu Chi
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
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Yi-Fan Chen
Yi-Fan Chen
Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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Wei-Che Lin
Wei-Che Lin
Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan
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Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan
Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan
School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan
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/mL) 0.35–4.94 1.55 ± 0.92 1.52 ± 0.77 – 0.643 M, months; max., maximal; RR, reference range. ACR TI-RADS subgroups of Bethesda III nodules Repeat FNAC is recommended by the Bethesda system for reporting thyroid
Tamas Solymosi
Tamas Solymosi
Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary
Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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Laszlo Hegedűs
Laszlo Hegedűs
Department of Endocrinology, Odense University Hospital, Odense, Denmark
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Steen J Bonnema
Steen J Bonnema
Department of Endocrinology, Odense University Hospital, Odense, Denmark
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Andrea Frasoldati
Andrea Frasoldati
Endocrinology Unit of Arcispedale S Maria Nuova, Reggio Emilia, Italy
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Laszlo Jambor
Laszlo Jambor
Department of Radiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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Zsolt Karanyi
Zsolt Karanyi
Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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Gabor L Kovacs
Gabor L Kovacs
1st Department of Medicine, Flohr Ferenc Hospital, Kistarcsa, Hungary
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Enrico Papini
Enrico Papini
Regina Apostolorum Hospital in Albano, Rome, Italy
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Karoly Rucz
Karoly Rucz
1st Department of Medicine, University of Pecs, Pecs, Hungary
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Gilles Russ
Gilles Russ
Unité Thyroïde et Tumeurs Endocrines – Pr Leenhardt Hôpital La Pitie Salpetriere, Sorbonne Université, Paris, France
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Endre V Nagy
Endre V Nagy
Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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). The ranges regarding the reported frequency of suspicious characteristics in thyroid cancers vary: 20–100% for hypoechogenicity ( 4 , 6 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ), 14–41% for very hypoechoic nodules ( 6 , 19 , 20
Muhammad Fahad Arshad
Muhammad Fahad Arshad
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK
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University of Sheffield, Sheffield, UK
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Amardass Dhami
Amardass Dhami
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
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Gillian Quarrell
Gillian Quarrell
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
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Saba Prakash Balasubramanian
Saba Prakash Balasubramanian
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK
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University of Sheffield, Sheffield, UK
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according to whether they had PTH of ≥1.6 pmol/L (lower limit of normal reference range) at this time period, all of the those who recovered had PTH above this cut-off compared to 16/25 (64%) of the patients in the ongoing PoSH group ( P = 0
Milan Halenka
Milan Halenka
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Hana Munteanu
Hana Munteanu
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Radko Obereigneru
Radko Obereigneru
Faculty of Arts, Palacky University Olomouc, Olomouc, Czech Republic
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Roman Dohnal
Roman Dohnal
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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David Karasek
David Karasek
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Jan Schovanek
Jan Schovanek
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic
Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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was previously offered to all patients. All the patients demonstrated normal thyroid function (serum TSH in the reference range). Only one girl (15 years old) had Hashimoto’s disease with hypothyroidism, adequately treated with l -thyroxine. Exclusion
Tommaso Piticchio
Tommaso Piticchio
Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi Nesima Hospital, University of Catania, Catania, Italy
Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland
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Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland
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Gilles Russ
Gilles Russ
Department of Thyroid and Endocrine Tumor Diseases, La Pitie-Salpetriere Hospital, 83 Bd de l’Hopital, Paris, France
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Maija Radzina
Maija Radzina
Riga Stradins University, Radiology Research Laboratory, Riga, Latvia
University of Latvia, Faculty of Medicine, Riga, Latvia
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University of Latvia, Faculty of Medicine, Riga, Latvia
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Francesco Frasca
Francesco Frasca
Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi Nesima Hospital, University of Catania, Catania, Italy
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Cosimo Durante
Cosimo Durante
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Pierpaolo Trimboli
Pierpaolo Trimboli
Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland
Facoltà di Scienze Biomediche, Università della Svizzera Italiana (USI), Lugano, Switzerland
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Facoltà di Scienze Biomediche, Università della Svizzera Italiana (USI), Lugano, Switzerland
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that met the established inclusion criteria. References from the included studies were further screened for any additional papers. The final electronic search was conducted on June 14, 2023. The search of electronic databases was conducted without any
Radu Mihai
Radu Mihai
Department of Endocrine Surgery, Churchill Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
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may be imperceptible to clinicians who are not familiar with patients’ voice range but may be very significant for patients themselves. There is therefore a real need to explore the broader spectrum of patients’ own perception of voice morbidity after
