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Salman Razvi Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Endocrinology, Gateshead Health NHS Foundation Trust, Gateshead, UK

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Avais Jabbar Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Cardiology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

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Arjola Bano Department of Cardiology, Institute of Social and Preventive Medicine, University of Bern, Bern University Hospital, Bern, Switzerland

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Lorna Ingoe Department of Endocrinology, Gateshead Health NHS Foundation Trust, Gateshead, UK

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Peter Carey Departments of Endocrinology and Cardiology, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK

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Shahid Junejo Departments of Endocrinology and Cardiology, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK

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Honey Thomas Department of Cardiology, Northumbria Healthcare NHS Foundation Trust, Cramlington, UK

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Caroline Addison Department of Biochemistry, Gateshead Health NHS Foundation Trust, Gateshead, UK

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David Austin Department of Cardiology, South Tees Health NHS Foundation Trust, Middlesbrough, UK

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John P Greenwood Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK

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Azfar G Zaman Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Cardiology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

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.4%) deaths were observed. In the main model, lower FT3 levels at baseline were associated with a higher risk of mortality in a non-linear manner ( P   < 0.0001, P for non-linearity 0.048) ( Fig. 2 ). Visual inspection of the graph suggested that the slope

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