Search Results
Giorgio Radetti
Giorgio Radetti
Marienklinik, Bolzano, Italy
Search for other papers by Giorgio Radetti in
Google Scholar
PubMed
Search for other papers by Giorgio Radetti in
Google Scholar
PubMed
Franco Rigon
Franco Rigon
Department of Paediatrics, University of Padua, Padua, Italy
Search for other papers by Franco Rigon in
Google Scholar
PubMed
Search for other papers by Franco Rigon in
Google Scholar
PubMed
Alessandro Salvatoni
Alessandro Salvatoni
Department of Medicine and Surgery, University of Insubria, Varese, Italy
Search for other papers by Alessandro Salvatoni in
Google Scholar
PubMed
Search for other papers by Alessandro Salvatoni in
Google Scholar
PubMed
Irene Campi
Irene Campi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Search for other papers by Irene Campi in
Google Scholar
PubMed
Search for other papers by Irene Campi in
Google Scholar
PubMed
Tiziana De Filippis
Tiziana De Filippis
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Search for other papers by Tiziana De Filippis in
Google Scholar
PubMed
Search for other papers by Tiziana De Filippis in
Google Scholar
PubMed
Valentina Cirello
Valentina Cirello
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Search for other papers by Valentina Cirello in
Google Scholar
PubMed
Search for other papers by Valentina Cirello in
Google Scholar
PubMed
Silvia Longhi
Silvia Longhi
Department of Paediatrics, Regional Hospital of Bolzano, Bolzano, Italy
Search for other papers by Silvia Longhi in
Google Scholar
PubMed
Search for other papers by Silvia Longhi in
Google Scholar
PubMed
Fabiana Guizzardi
Fabiana Guizzardi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Search for other papers by Fabiana Guizzardi in
Google Scholar
PubMed
Search for other papers by Fabiana Guizzardi in
Google Scholar
PubMed
Marco Bonomi
Marco Bonomi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Marco Bonomi in
Google Scholar
PubMed
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Marco Bonomi in
Google Scholar
PubMed
Luca Persani
Luca Persani
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
demonstrated ( 4 , 5 , 6 , 7 ). RTHβ, firstly described by Refetoff in 1967 ( 8 ), is characterized by elevated circulating free thyroxine (fT4) and free tri-iodothyronine (fT3) together with an unsuppressed thyroid-stimulating hormone (TSH). RTHβ is
Luca Persani
Luca Persani
Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milano, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
Patrice Rodien
Patrice Rodien
Service d’Endocrinologie-Diabétologie-Nutrition, Centre de référence des maladies rares de la Thyroïde et des récepteurs hormonaux, CHU d’Angers, Angers, France.
Search for other papers by Patrice Rodien in
Google Scholar
PubMed
Search for other papers by Patrice Rodien in
Google Scholar
PubMed
Carla Moran
Carla Moran
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
Endocrine Section, Beacon Hospital, Dublin, Ireland.
School of Medicine, University College Dublin, Ireland
Endocrinology Department, St Vincent’s University Hospital, Dublin, Ireland
Search for other papers by Carla Moran in
Google Scholar
PubMed
Endocrine Section, Beacon Hospital, Dublin, Ireland.
School of Medicine, University College Dublin, Ireland
Endocrinology Department, St Vincent’s University Hospital, Dublin, Ireland
Search for other papers by Carla Moran in
Google Scholar
PubMed
W Edward Visser
W Edward Visser
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
Search for other papers by W Edward Visser in
Google Scholar
PubMed
Search for other papers by W Edward Visser in
Google Scholar
PubMed
Stefan Groeneweg
Stefan Groeneweg
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
Search for other papers by Stefan Groeneweg in
Google Scholar
PubMed
Search for other papers by Stefan Groeneweg in
Google Scholar
PubMed
Robin Peeters
Robin Peeters
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
Search for other papers by Robin Peeters in
Google Scholar
PubMed
Search for other papers by Robin Peeters in
Google Scholar
PubMed
Samuel Refetoff
Samuel Refetoff
Departments of Medicine and Paediatrics and Committee on Genetics, The University of Chicago, Chicago, Illinois, USA
Search for other papers by Samuel Refetoff in
Google Scholar
PubMed
Search for other papers by Samuel Refetoff in
Google Scholar
PubMed
Mark Gurnell
Mark Gurnell
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
Search for other papers by Mark Gurnell in
Google Scholar
PubMed
Search for other papers by Mark Gurnell in
Google Scholar
PubMed
Paolo Beck-Peccoz
Paolo Beck-Peccoz
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
Search for other papers by Paolo Beck-Peccoz in
Google Scholar
PubMed
Search for other papers by Paolo Beck-Peccoz in
Google Scholar
PubMed
Krishna Chatterjee
Krishna Chatterjee
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
Search for other papers by Krishna Chatterjee in
Google Scholar
PubMed
Search for other papers by Krishna Chatterjee in
Google Scholar
PubMed
screening for rare genetic and acquired disorders of thyroid hormone transport, metabolism, and action ( Recommendation: S; Quality of evidence: ØØØO). Dynamic endocrine tests (TRH stimulation (if available), L-T3 suppression), pituitary imaging (MRI
Sander Barnhoorn
Sander Barnhoorn
Department of Molecular Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
Search for other papers by Sander Barnhoorn in
Google Scholar
PubMed
Search for other papers by Sander Barnhoorn in
Google Scholar
PubMed
Marcel E Meima
Marcel E Meima
Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
Search for other papers by Marcel E Meima in
Google Scholar
PubMed
Search for other papers by Marcel E Meima in
Google Scholar
PubMed
Robin P Peeters
Robin P Peeters
Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
Search for other papers by Robin P Peeters in
Google Scholar
PubMed
Search for other papers by Robin P Peeters in
Google Scholar
PubMed
Veerle M Darras
Veerle M Darras
Laboratory of Comparative Endocrinology, Biology Department, KU Leuven, Leuven, Belgium
Search for other papers by Veerle M Darras in
Google Scholar
PubMed
Search for other papers by Veerle M Darras in
Google Scholar
PubMed
Selmar Leeuwenburgh
Selmar Leeuwenburgh
Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
Search for other papers by Selmar Leeuwenburgh in
Google Scholar
PubMed
Search for other papers by Selmar Leeuwenburgh in
Google Scholar
PubMed
Jan H J Hoeijmakers
Jan H J Hoeijmakers
Department of Molecular Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Oncode Institute, Utrecht, The Netherlands
Institute for Genome Stability in Ageing and Disease, CECAD Research Centre, Cologne, Germany
Search for other papers by Jan H J Hoeijmakers in
Google Scholar
PubMed
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Oncode Institute, Utrecht, The Netherlands
Institute for Genome Stability in Ageing and Disease, CECAD Research Centre, Cologne, Germany
Search for other papers by Jan H J Hoeijmakers in
Google Scholar
PubMed
Wilbert P Vermeij
Wilbert P Vermeij
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Oncode Institute, Utrecht, The Netherlands
Search for other papers by Wilbert P Vermeij in
Google Scholar
PubMed
Oncode Institute, Utrecht, The Netherlands
Search for other papers by Wilbert P Vermeij in
Google Scholar
PubMed
W Edward Visser
W Edward Visser
Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
Search for other papers by W Edward Visser in
Google Scholar
PubMed
Search for other papers by W Edward Visser in
Google Scholar
PubMed
changes during aging ( 2 , 3 , 4 , 5 ). In humans, thyroid-stimulating hormone (TSH) concentrations typically increase with age while concentrations of the bioactive T3 (triiodothyronine) decrease in the elderly population ( 3 , 5 ). Whether such
Eveline Bruinstroop
Eveline Bruinstroop
Department of Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands
Search for other papers by Eveline Bruinstroop in
Google Scholar
PubMed
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands
Search for other papers by Eveline Bruinstroop in
Google Scholar
PubMed
Anne H van der Spek
Anne H van der Spek
Department of Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands
Search for other papers by Anne H van der Spek in
Google Scholar
PubMed
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands
Search for other papers by Anne H van der Spek in
Google Scholar
PubMed
Anita Boelen
Anita Boelen
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
Search for other papers by Anita Boelen in
Google Scholar
PubMed
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
Search for other papers by Anita Boelen in
Google Scholar
PubMed
no Dio1 activity in the liver, kidney, and thyroid ( 19 ). In both models, a similar pattern of serum thyroid hormone levels was observed. Serum T3 and thyroid-stimulating hormone (TSH) concentrations remained within the normal range whereas serum T4
Sepehr Torabinejad
Sepehr Torabinejad
Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy
Search for other papers by Sepehr Torabinejad in
Google Scholar
PubMed
Search for other papers by Sepehr Torabinejad in
Google Scholar
PubMed
Caterina Miro
Caterina Miro
Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy
Search for other papers by Caterina Miro in
Google Scholar
PubMed
Search for other papers by Caterina Miro in
Google Scholar
PubMed
Biagio Barone
Biagio Barone
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II
Search for other papers by Biagio Barone in
Google Scholar
PubMed
Search for other papers by Biagio Barone in
Google Scholar
PubMed
Ciro Imbimbo
Ciro Imbimbo
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II
Search for other papers by Ciro Imbimbo in
Google Scholar
PubMed
Search for other papers by Ciro Imbimbo in
Google Scholar
PubMed
Felice Crocetto
Felice Crocetto
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II
Search for other papers by Felice Crocetto in
Google Scholar
PubMed
Search for other papers by Felice Crocetto in
Google Scholar
PubMed
Monica Dentice
Monica Dentice
Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy
CEINGE – Biotecnologie Avanzate Scarl, Naples, Italy
Search for other papers by Monica Dentice in
Google Scholar
PubMed
CEINGE – Biotecnologie Avanzate Scarl, Naples, Italy
Search for other papers by Monica Dentice in
Google Scholar
PubMed
thyroxine, thyroid-stimulating hormone, and hypothyroid status and the risk of prostate cancer . PLoS One 2012 7 e47730. ( https://doi.org/10.1371/journal.pone.0047730 ) 40 Tran TV Kitahara CM de Vathaire F Boutron-Ruault MC & Journy N
Juan Ren
Juan Ren
ENS de Lyon, INRAE, CNRS, Institut de Génomique Fonctionnelle de Lyon, Lyon, France
Search for other papers by Juan Ren in
Google Scholar
PubMed
Search for other papers by Juan Ren in
Google Scholar
PubMed
Frédéric Flamant
Frédéric Flamant
ENS de Lyon, INRAE, CNRS, Institut de Génomique Fonctionnelle de Lyon, Lyon, France
Search for other papers by Frédéric Flamant in
Google Scholar
PubMed
Search for other papers by Frédéric Flamant in
Google Scholar
PubMed
-Lasselin C Riviere J Gilles M Chassande O Morgenthaler C Laloe D Lecardonnel J Flamant F Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone . Endocrinology 2014 155 3123 – 3135 . ( https://doi.org/10.1210/en
Yalan Hu
Yalan Hu
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Search for other papers by Yalan Hu in
Google Scholar
PubMed
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Search for other papers by Yalan Hu in
Google Scholar
PubMed
Kim Falize
Kim Falize
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Kim Falize in
Google Scholar
PubMed
Search for other papers by Kim Falize in
Google Scholar
PubMed
A S Paul van Trotsenburg
A S Paul van Trotsenburg
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by A S Paul van Trotsenburg in
Google Scholar
PubMed
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by A S Paul van Trotsenburg in
Google Scholar
PubMed
Raoul Hennekam
Raoul Hennekam
Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Raoul Hennekam in
Google Scholar
PubMed
Search for other papers by Raoul Hennekam in
Google Scholar
PubMed
Eric Fliers
Eric Fliers
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Department of Endocrinology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Eric Fliers in
Google Scholar
PubMed
Department of Endocrinology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Eric Fliers in
Google Scholar
PubMed
Eveline Bruinstroop
Eveline Bruinstroop
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Department of Endocrinology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Eveline Bruinstroop in
Google Scholar
PubMed
Department of Endocrinology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Search for other papers by Eveline Bruinstroop in
Google Scholar
PubMed
Anita Boelen
Anita Boelen
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Search for other papers by Anita Boelen in
Google Scholar
PubMed
Amsterdam Gastroenterology, Endocrinology & Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands
Search for other papers by Anita Boelen in
Google Scholar
PubMed
differences in serum thyroxine (T4), triiodothyronine (T3) and thyroid-stimulating-hormone (TSH) concentrations were observed between Tbl1xr1 Y446C/Y446C and wild type (WT) mice ( 6 ). There were no serum TH abnormalities reported in Pierpont patients or
Ángel García-Aldea
Ángel García-Aldea
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Ángel García-Aldea in
Google Scholar
PubMed
Search for other papers by Ángel García-Aldea in
Google Scholar
PubMed
Marina Guillén-Yunta
Marina Guillén-Yunta
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Marina Guillén-Yunta in
Google Scholar
PubMed
Search for other papers by Marina Guillén-Yunta in
Google Scholar
PubMed
Víctor Valcárcel-Hernández
Víctor Valcárcel-Hernández
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Víctor Valcárcel-Hernández in
Google Scholar
PubMed
Search for other papers by Víctor Valcárcel-Hernández in
Google Scholar
PubMed
Ana Montero-Pedrazuela
Ana Montero-Pedrazuela
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Ana Montero-Pedrazuela in
Google Scholar
PubMed
Search for other papers by Ana Montero-Pedrazuela in
Google Scholar
PubMed
Ana Guadaño-Ferraz
Ana Guadaño-Ferraz
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Ana Guadaño-Ferraz in
Google Scholar
PubMed
Search for other papers by Ana Guadaño-Ferraz in
Google Scholar
PubMed
Soledad Bárez-López
Soledad Bárez-López
Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain
Search for other papers by Soledad Bárez-López in
Google Scholar
PubMed
Search for other papers by Soledad Bárez-López in
Google Scholar
PubMed
concentrations of T3, low T4, and rT3, and normal or slightly high levels of thyroid-stimulating hormone (TSH), indicating that there are also alterations in TH synthesis and metabolism ( 12 ). The restricted TH entry to the brain and the subsequent dysregulation
Yingxin Fang
Yingxin Fang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Yingxin Fang in
Google Scholar
PubMed
Search for other papers by Yingxin Fang in
Google Scholar
PubMed
Pingping Dang
Pingping Dang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Pingping Dang in
Google Scholar
PubMed
Search for other papers by Pingping Dang in
Google Scholar
PubMed
Yue Liang
Yue Liang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Yue Liang in
Google Scholar
PubMed
Search for other papers by Yue Liang in
Google Scholar
PubMed
Defa Zhao
Defa Zhao
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Defa Zhao in
Google Scholar
PubMed
Search for other papers by Defa Zhao in
Google Scholar
PubMed
Ranran Wang
Ranran Wang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Ranran Wang in
Google Scholar
PubMed
Search for other papers by Ranran Wang in
Google Scholar
PubMed
Yue Xi
Yue Xi
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
Search for other papers by Yue Xi in
Google Scholar
PubMed
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
Search for other papers by Yue Xi in
Google Scholar
PubMed
Dan Zhang
Dan Zhang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
Search for other papers by Dan Zhang in
Google Scholar
PubMed
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
Search for other papers by Dan Zhang in
Google Scholar
PubMed
Wei Wang
Wei Wang
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Wei Wang in
Google Scholar
PubMed
Search for other papers by Wei Wang in
Google Scholar
PubMed
Zhongyan Shan
Zhongyan Shan
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Zhongyan Shan in
Google Scholar
PubMed
Search for other papers by Zhongyan Shan in
Google Scholar
PubMed
Weiping Teng
Weiping Teng
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Weiping Teng in
Google Scholar
PubMed
Search for other papers by Weiping Teng in
Google Scholar
PubMed
Xiaochun Teng
Xiaochun Teng
Department of Endocrinology and Metabolism, Institute of Endocrine, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, People’s Republic of China
Search for other papers by Xiaochun Teng in
Google Scholar
PubMed
Search for other papers by Xiaochun Teng in
Google Scholar
PubMed
Introduction Thyroid hormones (THs, namely, the prohormone thyroxine T4 and its active form, triiodothyronine T3) play pivotal roles in diverse aspects of life, mainly during development, when they regulate skeletal growth, cardiac function
Zhongli Chen
Zhongli Chen
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Zhongli Chen in
Google Scholar
PubMed
Search for other papers by Zhongli Chen in
Google Scholar
PubMed
Robin P Peeters
Robin P Peeters
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Robin P Peeters in
Google Scholar
PubMed
Search for other papers by Robin P Peeters in
Google Scholar
PubMed
Wesley Flach
Wesley Flach
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Wesley Flach in
Google Scholar
PubMed
Search for other papers by Wesley Flach in
Google Scholar
PubMed
Linda J de Rooij
Linda J de Rooij
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Linda J de Rooij in
Google Scholar
PubMed
Search for other papers by Linda J de Rooij in
Google Scholar
PubMed
Sena Yildiz
Sena Yildiz
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Sena Yildiz in
Google Scholar
PubMed
Search for other papers by Sena Yildiz in
Google Scholar
PubMed
Alexander Teumer
Alexander Teumer
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Search for other papers by Alexander Teumer in
Google Scholar
PubMed
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Search for other papers by Alexander Teumer in
Google Scholar
PubMed
Matthias Nauck
Matthias Nauck
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany
Search for other papers by Matthias Nauck in
Google Scholar
PubMed
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany
Search for other papers by Matthias Nauck in
Google Scholar
PubMed
Rosalie B T M Sterenborg
Rosalie B T M Sterenborg
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Search for other papers by Rosalie B T M Sterenborg in
Google Scholar
PubMed
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Search for other papers by Rosalie B T M Sterenborg in
Google Scholar
PubMed
Joost H W Rutten
Joost H W Rutten
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Search for other papers by Joost H W Rutten in
Google Scholar
PubMed
Search for other papers by Joost H W Rutten in
Google Scholar
PubMed
Marco Medici
Marco Medici
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Search for other papers by Marco Medici in
Google Scholar
PubMed
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Search for other papers by Marco Medici in
Google Scholar
PubMed
W Edward Visser
W Edward Visser
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by W Edward Visser in
Google Scholar
PubMed
Search for other papers by W Edward Visser in
Google Scholar
PubMed
Marcel E Meima
Marcel E Meima
Department of Internal Medicine, Academic Centre for Thyroid Diseases, Erasmus University Medical Center Rotterdam, The Netherlands
Search for other papers by Marcel E Meima in
Google Scholar
PubMed
Search for other papers by Marcel E Meima in
Google Scholar
PubMed
necessarily mean it has no physiological relevance. For example, common genetic variation in MCT8 , mutations which cause neurocognitive phenotypes, has no association with thyroid stimulating hormone (TSH) or FT4 levels ( 14 ). A second process for which
