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the present case, this hypothesis is unlikely considering that TRAb and TPOAb were negative in April 2020 and thyrotropin level was normal until 2 weeks prior to vaccination. Vaccine-induced autoimmunity has been previously described, notably for
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.1159/000490384 ) 3 Fröhlich E & Wahl R . Thyroid autoimmunity: role of anti-thyroid antibodies in thyroid and extra-thyroidal diseases . Frontiers in Immunology 2017 8 521 . ( https://doi.org/10.3389/fimmu.2017.00521 ) 4 Pearce EN Farwell AP
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patients, and current evidence is insufficient to draw any conclusion on this issue ( 13 ). Hyperthyroidism is mostly caused by autoimmunity in GD or by one or more autonomously functioning thyroid nodules in TNG ( 36 ). Since these conditions differ with
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autoimmunity . Endocrine 2012 42 252 – 265 . ( https://doi.org/10.1007/s12020-012-9703-2 ) 11 Ross DS Burch HB Cooper DS Greenlee MC Laurberg P Maia AL Rivkees SA Samuels M Sosa JA Stan MN , 2016 American Thyroid Association guidelines
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://doi.org/10.1210/jc.2017-00166 ) 21 Ricci D Brancatella A Marinò M Rotondi M Chiovato L Vitti P Latrofa F . The detection of serum IgMs to thyroglobulin in subacute thyroiditis suggests a protective role of IgMs in thyroid autoimmunity
Institute of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden
Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden
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Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden
Gothenburg Centre for Person Centred-Care (GPCC), Göteborg, Sweden
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depression or anxiety in hyperthyroid individuals ( 24 ). Thus, the evidence for an association between thyroid hormone levels and mental symptoms in GD is inconclusive. Supporting thyroid-related antibodies or autoimmunity per se as a causative factor for
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. Autoimmunity in patients with resistance to thyroid hormone . Journal of Clinical Endocrinology and Metabolism 2010 95 3189 – 3193 . ( https://doi.org/10.1210/jc.2009-2179 ) 35 Gavin C Meggison H & Ooi TC . Proposing a causal link between thyroid