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Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
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Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
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Introduction The large majority of patients with non-medullary thyroid carcinoma (NMTC) have an excellent prognosis and achieve remission after conventional treatment by surgery, radioactive iodine (RAI) treatment, and levothyroxine
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Department of Nuclear Medicine, The First Hospital of Jilin University, Changchun, China
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Department of Nuclear Medicine & Minnan PET Center, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
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progressive RR-DTC lesions were eligible for enrollment. As described by our team, the diagnosis of RR-DTC relied on one of the following: (i) the foci did not concentrate 131 I; (ii) despite previous evidence of 131 I concentration, the foci lost the
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by radioactive iodine ( 131 I) and thyroid-stimulating hormone suppression therapy ( 2 , 3 , 4 ). However, 15–33% of DTC patients have a primary iodine refractory-differentiated thyroid cancer (IR-DTC) or develop IR-DTC after several sessions of
Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China
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kDa and is produced and released by thyroid follicular epithelial cells ( 9 ). In 1992, Pacini et al. first suggested that elevated concentrations of Tg in fine needle aspirate washout (FNA-Tg) of nonthyroidal neck nodes could assist in the diagnosis
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Department of Emergency Medicine, Maastricht University Medical Center, Maastricht, the Netherlands
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assay without TgAb interference would be ideal because it could give more certainty regarding the correct Tg concentration and, expectedly, the DTC patients’ disease state. Against this background, a promising technique is liquid chromatography
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-, and post-operative findings. They are useful in deciding therapeutic strategies, including the extent of surgery, adjuvant therapies such as radioactive iodine (RAI) administration, and postoperative follow-up imaging studies. Based on the 8th Edition