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Maja Hjelm Lundgaard
Maja Hjelm Lundgaard
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Allan Carlé
Allan Carlé
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Ulla Birgitte Christiansen
Ulla Birgitte Christiansen
Department of Gynaecology and Obstetrics, Aalborg University Hospital, Aalborg, Denmark
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Anne Sørensen
Anne Sørensen
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Gynaecology and Obstetrics, Aalborg University Hospital, Aalborg, Denmark
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Department of Gynaecology and Obstetrics, Aalborg University Hospital, Aalborg, Denmark
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Søren Risom Kristensen
Søren Risom Kristensen
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Stine Linding Andersen
Stine Linding Andersen
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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signs of goiter. Assessment of thyroid autoantibodies showed markedly elevated thyroid peroxidase antibodies (TPO-Ab) as well as elevated thyroglobulin antibodies (Tg-Ab) ( Table 2 ) indicating that the etiology of hypothyroidism in this patient was most
Cengiz Kara
Cengiz Kara
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Pediatric Endocrinology, Faculty of Medicine, Istinye University, Istanbul, Turkey
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Department of Pediatric Endocrinology, Faculty of Medicine, Istinye University, Istanbul, Turkey
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Jamala Mammadova
Jamala Mammadova
Pediatric Endocrinology Unit, Altinbas University Medicalpark Bahçelievler Hospital, Istanbul, Turkey
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Ümmet Abur
Ümmet Abur
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Cagri Gumuskaptan
Cagri Gumuskaptan
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Department of Medical Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Elif İzci Güllü
Elif İzci Güllü
Department of Pediatric Endocrinology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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Ayhan Dağdemir
Ayhan Dağdemir
Department of Molecular Medicine, Institute of Graduate Studies, Ondokuz Mayis University, Samsun, Turkey
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Murat Aydın
Murat Aydın
Department of Pediatric Endocrinology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
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.7–100) 100 (40.4–100) 0.12 Free T4 (RR: 0.89–2.2 ng/dL) c 0.62 ± 0.33 0.81 ± 0.39 0.04 Free T3 (RR: 1.95–6.0 pg/mL) c 2.97 ± 1.29 4.02 ± 2.06 0.12 Thyroglobulin (RR: 20–228 ng/mL) 5.0 (1.3–17.8) 300 (142–300) <0
Paolo Cavarzere
Paolo Cavarzere
Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
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Laura Palma
Laura Palma
Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
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Lara Nicolussi Principe
Lara Nicolussi Principe
Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
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Monica Vincenzi
Monica Vincenzi
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy
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Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy
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Silvana Lauriola
Silvana Lauriola
Neonatal Intensive Cure Unit, Department of Pediatrics, University Hospital of Verona, Verona, Italy
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Rossella Gaudino
Rossella Gaudino
Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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Virginia Murri
Virginia Murri
Pediatric Division, Hospital of San Bonifacio, Verona, Italy
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Luigi Lubrano
Luigi Lubrano
Pediatric Division, Hospital of Legnago, Verona, Italy
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Giuliana Rossi
Giuliana Rossi
Pediatric Division, Hospital of Mestre, Venezia, Italy
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Alessia Sallemi
Alessia Sallemi
Pediatric Division, Hospital of Venezia, Venezia, Italy
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Ermanna Fattori
Ermanna Fattori
Pediatric Division, Hospital of Negrar, Verona, Italy
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Marta Camilot
Marta Camilot
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy
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Regional Center for Newborn Screening, Diagnosis and Treatment of Congenital Metabolic and Endocrinological Diseases, Verona, Italy
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Franco Antoniazzi
Franco Antoniazzi
Pediatric Division, Department of Pediatrics, University Hospital of Verona, Verona, Italy
Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for the Diagnosis and Treatment of Children and Adolescents Rare Skeletal Disorders, Pediatric Clinic, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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Pediatric Section, Department Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
Regional Center for the Diagnosis and Treatment of Children and Adolescents Rare Skeletal Disorders, Pediatric Clinic, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy
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anti-thyroid antibodies against thyroid peroxidase (TPOAb), thyroglobulin (TGAb), and/or thyrotropin receptor (TRAb). Its overall prevalence is 7.8%, ranging from 5 to 20% in different studies ( 5 ). TPOAbs cross the placenta, but it is not currently
Irene Campi
Irene Campi
Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
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Marco Dell’Acqua
Marco Dell’Acqua
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Elisa Stellaria Grassi
Elisa Stellaria Grassi
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Maria Cristina Vigone
Maria Cristina Vigone
Department of Paediatrics, IRCCS San Raffaele Hospital, Milan, Italy
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Luca Persani
Luca Persani
Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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amiodarone treatment. AD, autosomal dominant; AITD autoimmune thyroid diseases; L-T4, levothyroxine; MRI, magnetic resonance imaging; SHBG, sex hormone-binding globulin; SSA-LAR, long-acting somatostatin analog; Tg-Ab, anti-thyroglobulin antibodies; TPO
Kamilla R Riis
Kamilla R Riis
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Camilla B Larsen
Camilla B Larsen
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Bjarke R Medici
Bjarke R Medici
Department of Medicine, Copenhagen University Hospital – Herlev and Gentofte, Denmark
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Christian Z Jensen
Christian Z Jensen
Department of Medicine, Copenhagen University Hospital – Herlev and Gentofte, Denmark
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Kristian H Winther
Kristian H Winther
Department of Endocrinology, Odense University Hospital, Odense, Denmark
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Emil L Larsen
Emil L Larsen
Department of Clinical Pharmacology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Denmark
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Christina Ellervik
Christina Ellervik
Department of Laboratory Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, United States of America
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Data and Data Support, Region Zealand, Sorø, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Data and Data Support, Region Zealand, Sorø, Denmark
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Jeppe L la Cour
Jeppe L la Cour
Department of Medicine, Copenhagen University Hospital – Herlev and Gentofte, Denmark
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Thomas H Brix
Thomas H Brix
Department of Endocrinology, Odense University Hospital, Odense, Denmark
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Henrik E Poulsen
Henrik E Poulsen
Department of Endocrinology, Copenhagen University Hospital, Bispebjerg-Frederiksberg Hospital, Denmark
Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
Department of Cardiology, University Hospital Nordsjælland, Hillerød, Denmark
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Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
Department of Cardiology, University Hospital Nordsjælland, Hillerød, Denmark
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Filip K Knop
Filip K Knop
Department of Medicine, Copenhagen University Hospital – Herlev and Gentofte, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Birte Nygaard
Birte Nygaard
Department of Medicine, Copenhagen University Hospital – Herlev and Gentofte, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Steen J Bonnema
Steen J Bonnema
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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diagnosed with autoimmune thyroiditis to meet the inclusion criteria. Autoimmune thyroiditis was defined by positive antibodies against thyroid peroxidase (TPOAb) or thyroglobulin in serum. Hypothyroidism was defined as overt (plasma thyrotropin (TSH) above
Hicham Benabdelkamel
Hicham Benabdelkamel
Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
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Malak A Jaber
Malak A Jaber
Pharmaceutical Medicinal Chemistry & Pharmacognosy, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan
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Lina A Dahabiyeh
Lina A Dahabiyeh
Division of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan
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Afshan Masood
Afshan Masood
Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
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Reem H Almalki
Reem H Almalki
Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
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Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
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Mohthash Musambil
Mohthash Musambil
Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
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Anas M Abdel Rahman
Anas M Abdel Rahman
Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Medicine, College of Medicine and King Saud Medical City, King Saud University, Riyadh, Saudi Arabia
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Department of Medicine, College of Medicine and King Saud Medical City, King Saud University, Riyadh, Saudi Arabia
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Assim A Alfadda
Assim A Alfadda
Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
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Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
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-stimulating hormone (TSH), total T 4 and T 3 , and free T 4 (FT 4 ) and T 3 . The other tests for thyroid antibodies and thyroglobulin identify autoimmune thyroid conditions and thyroiditis, respectively ( 4 ). Hypothyroidism, or an underactive thyroid, is a
Anita Boelen
Anita Boelen
Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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Nitash Zwaveling-Soonawala
Nitash Zwaveling-Soonawala
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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Annemieke C Heijboer
Annemieke C Heijboer
Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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A S Paul van Trotsenburg
A S Paul van Trotsenburg
Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands
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A4, Pendrin AD CH due to thyroid dyshormonogenesis – Tg Thyroglobulin AD CH due to thyroid dyshormonogenesis – DEHAL1 Iodotyrosine dehalogenase 1 AD CH due to thyroid dyshormonogenesis Intellectual deficits
Camilla Bøgelund Larsen
Camilla Bøgelund Larsen
Department of Endocrinology, Odense University Hospital, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Kristian Hillert Winther
Kristian Hillert Winther
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Per Karkov Cramon
Per Karkov Cramon
Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Institute of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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Institute of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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Nils Jakob Knudsen
Nils Jakob Knudsen
Department of Endocrinology, Bispebjerg University Hospital, Copenhagen, Denmark
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Jakob Bue Bjorner
Jakob Bue Bjorner
Department of Public Health, Copenhagen University, Copenhagen, Denmark
QualityMetric Inc, Johnston, Lincoln, Rhode Island, USA
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QualityMetric Inc, Johnston, Lincoln, Rhode Island, USA
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Lutz Schomburg
Lutz Schomburg
Institute for Experimental Endocrinology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
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Kamil Demircan
Kamil Demircan
Institute for Experimental Endocrinology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
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Thilo Samson Chillon
Thilo Samson Chillon
Institute for Experimental Endocrinology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
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Jeppe Gram
Jeppe Gram
Medical Department, Endocrinology, University Hospital of South-West Jutland, Esbjerg, Denmark
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Stinus Gadegaard Hansen
Stinus Gadegaard Hansen
Medical Department, Endocrinology, University Hospital of South-West Jutland, Esbjerg, Denmark
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Frans Brandt
Frans Brandt
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Internal Medicine Research Unit, University Hospital of Southern Jutland, Aabenraa, Denmark
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Internal Medicine Research Unit, University Hospital of Southern Jutland, Aabenraa, Denmark
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Birte Nygaard
Birte Nygaard
Department of Endocrinology, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
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Torquil Watt
Torquil Watt
Department of Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Institute of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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Institute of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Steen Joop Bonnema
Steen Joop Bonnema
Department of Endocrinology, Odense University Hospital, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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peroxidase (TPOAb) and/or thyroglobulin ( 2 ). The prevalence of overt hypothyroidism ranges between 0.2% and 5.3% in Europe, depending on geography, gender, age, and genetic factors ( 1 ). The standard treatment is lifelong levothyroxine (LT4) substitution
Tal Almagor
Tal Almagor
Pediatric Endocrine Institute, Ha’Emek Medical Center, Afula, Israel
Pediatric Department B, Ha’Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Pediatric Department B, Ha’Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Shoshana Rath
Shoshana Rath
Pediatric Endocrine Institute, Ha’Emek Medical Center, Afula, Israel
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Dan Nachtigal
Dan Nachtigal
Department of Otolaryngology, Head and Neck Surgery, Ha’Emek Medical Center, Afula, Israel
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Zohara Sharroni
Zohara Sharroni
Department of Otolaryngology, Head and Neck Surgery, Ha’Emek Medical Center, Afula, Israel
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Ghadir Elias-Assad
Ghadir Elias-Assad
Pediatric Endocrine Institute, Ha’Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Ora Hess
Ora Hess
Pediatric Endocrine Institute, Ha’Emek Medical Center, Afula, Israel
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Gilad Havazelet
Gilad Havazelet
Clalit Health Services, North District, Israel
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Yoav Zehavi
Yoav Zehavi
Pediatric Department B, Ha’Emek Medical Center, Afula, Israel
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Ronen Spiegel
Ronen Spiegel
Pediatric Department B, Ha’Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Dani Bercovich
Dani Bercovich
Faculty of Medical Science, Tel Hai Academic College Upper Galilee, Tel Hai, Israel
GGA – Galil Genetic Analysis Laboratory Ltd., Kazerin, Israel
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GGA – Galil Genetic Analysis Laboratory Ltd., Kazerin, Israel
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Shlomo Almashanu
Shlomo Almashanu
The National Newborn Screening Program, Ministry of Health, Tel-HaShomer, Israel
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Yardena Tenenbaum-Rakover
Yardena Tenenbaum-Rakover
Pediatric Endocrine Institute, Ha’Emek Medical Center, Afula, Israel
Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
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. Results Characteristics of the patients diagnosed with CH are given in Table 1 . CH was caused by thyroid dysgenesis in 62% (agenesis or ectopic thyroid), dyshormonogenesis in 29% (thyroid peroxidase [ TPO ], TSH receptor [ TSHR ], or thyroglobulin
Solène Castellnou
Solène Castellnou
Hospices Civils de Lyon, Groupement Hospitalier Est, Fédération d’Endocrinologie, Bron, France
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Patricia Bretones
Patricia Bretones
Service d’Endocrinologie Pédiatrique, Hospices Civils de Lyon, Groupement Hospitalier Est, Bron, France
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Juliette Abeillon
Juliette Abeillon
Hospices Civils de Lyon, Groupement Hospitalier Est, Fédération d’Endocrinologie, Bron, France
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Myriam Moret
Myriam Moret
Hospices Civils de Lyon, Groupement Hospitalier Est, Fédération d’Endocrinologie, Bron, France
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Pauline Perrin
Pauline Perrin
Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Groupement Hospitalier Est, LBMMS, Bron, France
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Karim Chikh
Karim Chikh
Centre de Biologie et de Pathologie Sud, Hospices Civils de Lyon, Groupement Hospitalier Sud, LBMMS, Saint Genis Laval, France
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Véronique Raverot
Véronique Raverot
Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Groupement Hospitalier Est, LBMMS, Bron, France
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the reference range (<1.75 IU/L). Anti-thyroglobulin antibodies were less than 25 IU/mL (reference range <115) and thyroglobulin level was 9.4 µg/L (reference range 3.5–77). The thyroid gland was eutopic with a normal size on cervical ultrasonography
