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Ilisimatusarfik, University of Greenland, Nuuk, Greenland
National Board of Health, Nuuk, Greenland
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Ilisimatusarfik, University of Greenland, Nuuk, Greenland
Department of Internal Medicine, Queen Ingrid’s Hospital, Nuuk, Greenland
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Queen Ingrid’s Health Care Centre, Nuuk, Greenland
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Ilisimatusarfik, University of Greenland, Nuuk, Greenland
Department of Internal Medicine, Queen Ingrid’s Hospital, Nuuk, Greenland
Department of Geriatric Medicine, Aalborg University Hospital, Aalborg, Denmark
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.3109/00365513.2014.965737 ) 17 Bülow Pedersen IB Knudsen N Jørgensen T Perrild H Ovesen L Laurberg P . Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiency . Clinical Endocrinology 2003 58 36
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Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan
Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
Center of Anti-Aging and Health Consultation, National Taiwan University Hospital, Taipei, Taiwan
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DM was diagnosed in patients with hyperglycemia meeting the diagnostic criteria of DM, confirmed poor islet cell reserve by the glucagon test, and the presence of autoantibodies against glutamic acid decarboxylase or tyrosine phosphatase if available
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too far apart to be involved by single autoantibody complementarity-determining regions based on previous modeling ( 14 , 20 ). Thyroglobulin (Tg) Tg is the largest and most abundant autoantigen in the thyroid gland. It is a soluble
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Introduction Hashimoto’s thyroiditis (HT) is an organ-specific autoimmune disease characterized by increased levels of thyroglobulin antibody (TgAb) and thyroid peroxidase antibody (TPOAb), which primarily belong to the IgG class ( 1
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
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Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Public Health Unit, ACES Baixo Mondego, Coimbra, Portugal
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Department of Endocrinology, Hospital University Centre of São João, Porto, Portugal
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Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto, Porto, Portugal
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antioxidant and anti-inflammatory effects of selenoproteins motivate the use of selenium supplementation (Se-Su) in the treatment of both HT and GD ( 9 ). It was hypothesised that low Se dietary levels enhanced the development of thyroid autoantibodies ( 12
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
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, including the accessibility of eligible participants during the study period and the feasibility of collecting data. Patients with elevated serum thyroid autoantibodies (thyroid peroxidase antibodies (TPOAb) >200 IU/mL and/or anti-thyroglobulin antibodies
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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thyroxine, thyroid-stimulating hormone (TSH), TSH receptor autoantibodies (TRAb), thyroid peroxidase antibody, and thyroglobulin antibody are shown as median and quartiles of the original values and log10 normal transformed before statistical analysis. For