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Sara Monteiro-Martins Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany

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Rosalie B T M Sterenborg Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Oleg Borisov Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany

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Nora Scherer Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany

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Yurong Cheng Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany

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Marco Medici Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Anna Köttgen Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center – University of Freiburg, Freiburg, Germany
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

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Alexander Teumer Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany

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Introduction Thyroid hormones (TH) affect cellular metabolism and thereby have vital functions for growth and metabolic homeostasis ( 1 ). Thyroid function is governed by the hypothalamic–pituitary–thyroid (HPT) axis, where the thyrotropin

Article Type:
Research Article
Collections:
Genetics and omics in thyroidology
DOI:
https://doi.org/10.1530/ETJ-24-0067
Volume/Issue:
Volume 13: Issue 3
Open access
Min Ren Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Qianlan Yao Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Longlong Bao Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Zhiting Wang Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Ran Wei Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Qianming Bai Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Bo Ping Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Cai Chang Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Ultrasound, Fudan University Shanghai Cancer Center, Shanghai, China

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Yu Wang Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China

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Xiaoyan Zhou Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Xiaoli Zhu Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

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Introduction With the increasingly available and progressively sensitive use of ultrasonography, thyroid cancer is one of the fastest growing types of malignancy worldwide and is especially prevalent among the young and adolescents, ranking

Article Type:
Research Article
Collections:
Genetics and omics in thyroidology
DOI:
https://doi.org/10.1530/ETJ-21-0124
Volume/Issue:
Volume 11: Issue 3
Open access
Giulia Brigante Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria, Modena, Italy

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Clara Lazzaretti Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Elia Paradiso Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Federico Nuzzo Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Martina Sitti Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Frank Tüttelmann Institute of Reproductive Genetics, University of Münster, Münster, Germany

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Gabriele Moretti Department of Biology, University of Pisa, Pisa, Italy

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Roberto Silvestri Department of Biology, University of Pisa, Pisa, Italy

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Federica Gemignani Department of Biology, University of Pisa, Pisa, Italy

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Asta Försti Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany
Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany

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Kari Hemminki Biomedical Center, Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

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Rossella Elisei Department of Endocrinology, University Hospital, Pisa, Italy

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Cristina Romei Department of Endocrinology, University Hospital, Pisa, Italy

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Eric Adriano Zizzi PolitoBIO Med Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy

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Marco Agostino Deriu PolitoBIO Med Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy

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Manuela Simoni Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria, Modena, Italy
Center for Genomic Research, University of Modena and Reggio Emilia, Modena, Italy

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Stefano Landi Department of Biology, University of Pisa, Pisa, Italy

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Livio Casarini Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Center for Genomic Research, University of Modena and Reggio Emilia, Modena, Italy

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Introduction Thyroid cancer is the most common endocrine neoplasia with a worldwide estimated age-standardized incidence rate of 6.7 per 100,000 in 2018 ( 1 ). Differentiated thyroid carcinoma (DTC) is the most frequent subtype of thyroid

Article Type:
Research Article
Collections:
Genetics and omics in thyroidology
DOI:
https://doi.org/10.1530/ETJ-22-0058
Volume/Issue:
Volume 11: Issue 5
Open access
Fabyan Esberard de Lima Beltrão Lauro Wanderley University Hospital, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
University Center of João Pessoa – UNIPE, João Pessoa, PB, Brazil

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Daniele Carvalhal de Almeida Beltrão University Center of João Pessoa – UNIPE, João Pessoa, PB, Brazil
Post-Graduation Program in Cognitive Neuroscience and Behavior, Psychology Department of the Center of Human Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Giulia Carvalhal Center for Biological and Health Sciences, Federal University of Campina Grande, Campina Grande, Paraíba, Brazil

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Fabyanna Lethicia de Lima Beltrão Post-Graduate Program in Medicine and Health, Medical School of Medicine, Federal University of Bahia, Salvador, Brazil

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Jocyel de Brito Oliveira Bioregulation Department, Health and Science Institut, Federal University of Bahia, Salvador, Bahia, Brazil

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Hatilla dos Santos Silva Bioregulation Department, Health and Science Institut, Federal University of Bahia, Salvador, Bahia, Brazil

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Helena Mariana Pitangueira Teixeira Bioregulation Department, Health and Science Institut, Federal University of Bahia, Salvador, Bahia, Brazil

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Juliana Lopes Rodrigues Laboratory of Immunopharmacology and Molecular Biology, Health Sciences Institute, Federal University of Bahia, Brazil

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Camila Alexandrina Viana de Figueiredo Laboratory of Immunopharmacology and Molecular Biology, Health Sciences Institute, Federal University of Bahia, Brazil

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Ryan dos Santos Costa Laboratory of Immunopharmacology and Molecular Biology, Health Sciences Institute, Federal University of Bahia, Brazil

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Fabio Hecht The Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Giciane Carvalho Vieira Post-Graduation Program in Cognitive Neuroscience and Behavior, Psychology Department of the Center of Human Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Maria da Conceição Rodrigues Gonçalves Lauro Wanderley University Hospital, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Antonio C. Bianco Section of Endocrinology and Metabolism, Division of the Biological Sciences, University of Chicago, Chicago, Illinois, USA

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Helton Estrela Ramos Post-Graduate Program in Medicine and Health, Medical School of Medicine, Federal University of Bahia, Salvador, Brazil
Postgraduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, BA, Brazil

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-CoV-2). To infect the cells, the virus relies on a structural protein (Spike) that recognizes the angiotensin-converting enzyme 2 (ACE2) cell receptor ( 1 , 2 ), which is expressed in a wide range of tissues, including the thyroid gland ( 3 , 4

Article Type:
Research Article
Collections:
Genetics and omics in thyroidology
DOI:
https://doi.org/10.1530/ETJ-24-0068
Volume/Issue:
Volume 13: Issue 4
Open access