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INSERM 1086 ANTICIPE, Caen University, Caen, France
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thyroid nodules with indeterminate cytology, enabling malignancy in 18 FCH-negative nodules to be reliably excluded ( 3 ). Some cases of increased and diffuse 18 FCH uptake in the thyroid gland have been described in the imaging workup of patients with
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
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thyroid nodules or thyroid cancer ( 15 , 16 ). Furthermore, the involvement of thyroid-intrinsic clock in thyroid autoimmunity has not been evaluated. Hence, we hypothesized that there might be a reciprocal interaction between circadian disturbance and