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Isabelle Clinckspoor Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven

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Anne-Catherine Gérard Pôle de Morphologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain

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Jacqueline Van Sande IRIBHM, Université Libre de Bruxelles, Brussels

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Marie-Christine Many Pôle de Morphologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain

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Lieve Verlinden Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven

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Roger Bouillon Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven

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Geert Carmeliet Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven

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Chantal Mathieu Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Annemieke Verstuyf Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven

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Brigitte Decallonne Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Introduction 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ], the active form of vitamin D, is mainly known for its effects on calcium and phosphate homeostasis with bone, intestine and kidney as principal target tissues. However, 1,25(OH) 2 D 3

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Laura Fugazzola Department of Clinical Sciences and Community Health, University of Milan and Endocrine Unit, Fondazione IRCCS Ca' Granda, Milan, Italy

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Pg-stimulated Ct of 80 pg/ml for women and 500 pg/ml for men [ 12 ]. The Calcium Test The unavailability of Pg in the United States and recently also in most European countries recently raised the need to standardize other methods to stimulate

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Emilie Sonne-Holm Department of Otorhinolaryngology Surgery, Rigshospitalet University Hospital, Copenhagen, Denmark

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Christoffer Holst Hahn Department of Otorhinolaryngology Surgery, Rigshospitalet University Hospital, Copenhagen, Denmark

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surgery on thyroid cancers and intrathoracic goitres extending more than 5 cm substernally. Patients who underwent total thyroidectomy as part of laryngectomy or other comprehensive surgery or received calcium substitution prior to surgery were excluded

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Caroline M J van Kinschot Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands
Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Ivona Lončar Academic Center for Thyroid Diseases, Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Tessa M van Ginhoven Academic Center for Thyroid Diseases, Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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W Edward Visser Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Robin P Peeters Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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Charlotte van Noord Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands

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the Thyroid Network Study Group †
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the Thyroid Network Study Group

glands ( 1 , 2 ). The impaired parathyroid function is characterized by a decline in PTH and calcium concentrations during and shortly after thyroidectomy ( 3 ). In most patients parathyroid function fully recovers over time, but in 5

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Naohiro Araki Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Mitsuru Iida Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Nobuyuki Amino Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Shinji Morita Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Akane Ide Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Eijun Nishihara Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Mitsuru Ito Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Jun Saito Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan

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Tetsuo Nishikawa Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan

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Kiyonori Katsuragi Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Akira Miyauchi Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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TSHR, cyclic nucleotide-gated calcium channel and aequorin [ 10 , 11 ], tentatively named the aequorin TSAb assay. This assay can be started by simply thawing the frozen cells and does not require tissue culture facilities, which is beneficial for use

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Camille Galy-Bernadoy Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Benjamin Lallemant Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Guillaume Chambon Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Huy Trang Pham Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Christophe Reynaud Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Caroline Alovisetti Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Quentin Bonduelle Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital of Nîmes, Nîmes, France

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Anne Marie Guedj Department of Endocrinology and Metabolic Diseases, University Hospital of Nîmes, Nîmes, France

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Serge Lumbroso Department of Biochemistry and Molecular Biology, University Hospital of Nîmes, Nîmes, France

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David-Paul De Brauwere Department of Biochemistry and Molecular Biology, University Hospital of Nîmes, Nîmes, France

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closure (PTH SC), and the day after the procedure (PTH D1), corrected calcium on day 1 postoperatively and the following days if the patient stayed in hospital, occurrence of perioral paraesthesia and/or cramps evaluated by a visual analogue scale (VAS

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Lara Gut Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Selina Bernet Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Monika Huembelin Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Magdalena Mueller Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Ciril Baechli Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Daniel Koch Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Christian Nebiker Department of Surgery, Cantonal Hospital of Aarau, Aarau, Switzerland

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Philipp Schuetz Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Beat Mueller Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Emanuel Christ Division of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland

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Fahim Ebrahimi Division of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland
University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, Basel, Switzerland

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Alexander Kutz Division of Endocrinology, Diabetes, and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Division of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland

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all cases following thyroidectomy [ 4 , 6 , 7 ]. The most frequently reported adverse events after thyroidectomy are disorders of calcium homeostasis due to transient or permanent hypoparathyroidism, vocal cord paresis, and neck hematoma [ 7 - 10

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Muhammad Fahad Arshad Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK

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Amardass Dhami Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

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Gillian Quarrell Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

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Saba Prakash Balasubramanian Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
University of Sheffield, Sheffield, UK

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Introduction Hypoparathyroidism is defined as low calcium levels in presence of inappropriately normal or low parathyroid hormone (PTH) levels ( 1 ). It is commonly treated with calcium and activated vitamin D supplements, which makes it the

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Salvatore Benvenga Department of Clinical and Experimental Medicine, Italy
Master Program on Childhood, Adolescent and Women's Endocrine Health, University of Messina School of Medicine, Italy
Interdepartmental Program of Molecular and Clinical Endocrinology, and Women's Endocrine Health, University Hospital Policlinico G. Martino, Messina, Italy

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Roberto Vita Department of Clinical and Experimental Medicine, Italy

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Flavia Di Bari Department of Clinical and Experimental Medicine, Italy

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Poupak Fallahi Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Alessandro Antonelli Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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to us because, according to an endocrinologist consulted over the phone by her practitioner, she was likely to have some form of intestinal L -T4 malabsorption. After thyroidectomy, she was discharged with 100 μg/day of L -T4 plus 1 g/day of calcium

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Carla Colombo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Daniele Ceruti Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Simone De Leo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy

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Grzegorz Bilo Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

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Matteo Trevisan Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Noemi Giancola Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Claudia Moneta Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Gianfranco Parati Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

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Luca Persani Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Laura Fugazzola Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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inhibitors (ACE-i) followed by calcium channel blockers (CCBs) and beta-blockers (BBs) ( 27 ). In addition, some information on anti-hypertensive drugs and LEN reduction/interruption comes from a study on 25 patients on MKI treatment developing persistent

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