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Eun Kyung Jang Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Dong Eun Song Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Gyungyub Gong Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Jung Hwan Baek Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

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Yun Mi Choi Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Min Ji Jeon Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Ji Min Han Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Gu Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Tae Yong Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Young Kee Shong Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Bae Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Introduction Fine needle aspiration (FNA) is a rapid, cost-effective, and safe test, which is widely used for the diagnosis of thyroid nodules [ 1 ]. The positive predictive value of a malignant FNA cytology (FNAC) result is 97-99% according

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000353624
Volume/Issue:
Volume 2: Issue 3
Free access
Catherine Brophy Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Rania Mehanna Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Julie McCarthy Departments of Cytopathology, Cork University Hospital, Cork, Ireland

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Antoinette Tuthill Departments of Endocrinology, Cork University Hospital, Cork, Ireland

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Matthew S. Murphy Departments of Endocrinology, South Infirmary Victoria University Hospital, Cork, Ireland

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Patrick Sheahan Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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clinically apparent thyroid nodules is between 5 and 15% [ 2 ]. Fine-needle aspiration (FNA) cytology has demonstrated high utility in the diagnosis of thyroid nodules. In an effort to stratify thyroid nodules according to risk of malignancy in a consistent

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000441221
Volume/Issue:
Volume 4: Issue 4
Free access
Dorinda Mullen Department of Pathology, St. Vincent’s University Hospital, Dublin 4, Ireland

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Sarah Mullins Department of Pathology, St. Vincent’s University Hospital, Dublin 4, Ireland

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Aoife Doyle Department of Pathology, St. Vincent’s University Hospital, Dublin 4, Ireland

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Rachel K. Crowley Department of Endocrinology, St. Vincent’s University Hospital, Dublin 4, Ireland
School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland

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Stephen Skehan Department of Radiology, St. Vincent’s University Hospital, Dublin 4, Ireland
School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland

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Enda W. McDermott Department of Surgery, St. Vincent’s University Hospital, Dublin 4, Ireland
School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland

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Ruth S. Prichard Department of Surgery, St. Vincent’s University Hospital, Dublin 4, Ireland
School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland

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David Gibbons Department of Pathology, St. Vincent’s University Hospital, Dublin 4, Ireland
School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland

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aspirate (FNA) cytology has allowed for a minimally invasive yet diagnostically reliable means of triaging such lesions. Multiple cytology classification systems exist internationally, helping to streamline the reporting of these specimens, allowing for

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000478773
Volume/Issue:
Volume 6: Issue 5
Free access
Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia,” Udine

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Andrea Frasoldati Division of Endocrinology, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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FNA only in the presence of risk factors (FNA + risk factors vs. other options, p < 0.01). Follow-Up of a Cytologically Benign Nodule For a cytologically benign nodule, about 70% monitor at 12-24 months if low risk ( p < 0.01). If

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000453032
Volume/Issue:
Volume 6: Issue 2
Free access
Ana Isabel Álvarez-Mancha Department of Medicine, University of Malaga, Malaga, Spain
Department of Pathology, General University Hospital of Ciudad Real, Ciudad Real, Spain

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Isabel Mancha-Doblas Department of Medicine, University of Malaga, Malaga, Spain
Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain

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María Molina-Vega Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain
The Biomedical Research Institute of Malaga and Platform in Nanomedicine (IBIMA-BIONAND Platform), University of Malaga, Malaga, Spain

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Diego Fernández-García Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain

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Ana María Gómez-Pérez Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain
The Biomedical Research Institute of Malaga and Platform in Nanomedicine (IBIMA-BIONAND Platform), University of Malaga, Malaga, Spain

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Elena Gallego-Domínguez Department of Medicine, University of Malaga, Malaga, Spain
Department of Pathology, Virgen de la Victoria University Hospital, Málaga, Spain

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María Victoria Ortega-Jiménez Department of Medicine, University of Malaga, Malaga, Spain
Department of Pathology, Virgen de la Victoria University Hospital, Málaga, Spain

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Isabel Hierro-Martín Department of Pathology, Virgen de la Victoria University Hospital, Málaga, Spain

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Francisco J Tinahones Department of Medicine, University of Malaga, Malaga, Spain
Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain
The Biomedical Research Institute of Malaga and Platform in Nanomedicine (IBIMA-BIONAND Platform), University of Malaga, Malaga, Spain

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Introduction Clinical management of the thyroid nodules is based on a combination of clinical risk factors, functional status, ultrasound patterns, and cytologic findings when fine needle aspiration (FNA) is indicated ( 1 , 2 , 3 , 4 , 5

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-24-0076
Volume/Issue:
Volume 13: Issue 3
Open access
Francesco Boi Endocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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Fabiana Pani Endocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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Stefano Mariotti Endocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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cytology (FNAC) which are believed to be less subject to the potential selection bias of surgical series [ 10 , 11 ]. However, according to FNAC studies, the link between PTC and HT appears less evident. The aim of the present review will be to briefly

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000468928
Volume/Issue:
Volume 6: Issue 4
Free access
Ralf Paschke
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Silvia Cantara
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Anna Crescenzi
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Barbara Jarzab
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Thomas J. Musholt
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Manuel Sobrinho Simoes
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Introduction/Background Fine-needle aspiration (FNA) has high sensitivity and specificity in distinguishing benign from malignant thyroid lesions [ 1 ]. However, in 2–16% of cases cytology is not diagnostic [ 2 ], i.e., the material is

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000468519
Volume/Issue:
Volume 6: Issue 3
Free access
Tamas Solymosi Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Andrea Frasoldati Endocrinology Unit of Arcispedale S. Maria Nuova, Reggio Emilia, Italy

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Laszlo Jambor Department of Radiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Gabor Laszlo Kovacs 1st Department of Medicine, Flohr Ferenc Hospital, Kerepestarcsa, Hungary

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Enrico Papini Regina Apostolorum Hospital in Albano, Rome, Italy

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Karoly Rucz 1st Department of Medicine, University of Pecs, Pecs, Hungary

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Gilles Russ Unité Thyroïde et Tumeurs Endocrines – Pr Leenhardt Hôpital La Pitie Salpetriere, Sorbonne Université, Paris, France

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Zsolt Karanyi Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Endre V. Nagy Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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Introduction For more than three decades, the cornerstones in the clinical management of patients with thyroid nodules have been ultrasound (US) and fine-needle aspiration (FNA) cytology [ 1 - 5 ]. Robust evidence demonstrates that the risk of

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000511183
Volume/Issue:
Volume 10: Issue 5
Free access
Bülent Öcal Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Mehmet Hakan Korkmaz Department of Otolaryngology, Yıldırım Beyazıt University Medical School, Ankara, Turkey

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Demet Yılmazer Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Tuğba Taşkın Türkmenoğlu Department of Pathology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Ömer Bayır Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Güleser Saylam Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Emel Çadallı Tatar Department of Otolaryngology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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Sevilay Karahan Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, Turkey

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Erman Çakal Department of Endocrinology, Ministry of Health Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

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(< 1 cm) may harbor cancer. Therefore, every effort should be made either clinically or cytologically to predict malignancy in order to perform the appropriate surgery with the correct indication. It is critical to improve the diagnostic accuracy and

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000494720
Volume/Issue:
Volume 8: Issue 2
Free access
Maria Mavromati Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Verdiana Caironi Department of Internal Medicine, Lugano Regional Hospital, Ente Ospedaliero Cantonale, Via Tesserete Lugano, Switzerland

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Essia Saiji Department of Pathology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Maria-Isabel Vargas Department of Neuroradiology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Shahan Momjian Department of Neurosurgery, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Stephanie Andrade-Lopes Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Capucine Gubert Department of Internal Medicine, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Marco Stefano Demarchi Department of Thoracic and Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Ismini Mainta Department of Nuclear Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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François R Jornayvaz Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Kaveh Samii Department of Hematology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Grégoire Stalder Service and Central Laboratory of Hematology, Lausanne University Hospital, rue du Bugnon Lausanne, Switzerland.
Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland

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Sophie Leboulleux Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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, 3 , 4 , 5 , 6 , 7 ). Thyroid ultrasound-guided fine needle aspiration cytology (FNAC) can be a noninvasive and useful tool to confirm the diagnosis and prevent unnecessary transcranial biopsy ( 3 , 8 ). Here we present the case of a young

Article Type:
Case Report
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-24-0011
Volume/Issue:
Volume 13: Issue 3
Open access