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Patrick W. Owens Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Terri P. McVeigh Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
Cancer Genetics Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom

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Eoin J. Fahey Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Marcia Bell Department of Endocrinology, Galway University Hospital, Galway, Ireland

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Denis S. Quill Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Michael J. Kerin Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Aoife J. Lowery Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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radioactive iodine remnant ablation is associated with very low rates of structural disease recurrence in properly selected patients with differentiated thyroid cancer. Clin Endocrinol (Oxf) 2011; 75: 112–119. 15 Nixon IJ, Ganly I, Patel SG, Palmer FL

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Mathieu Spaas Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Brigitte Decallonne Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Annouschka Laenen Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium

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Jaak Billen Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

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Sandra Nuyts Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium

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Introduction The vast majority (> 90%) of thyroid carcinomas are differentiated thyroid cancer (DTC), which includes papillary (PTC) and follicular cancer (FTC), characterized by an indolent course and low mortality [ 1 ]. Primary management

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Aamna Hassan Departments of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

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Saima Riaz Departments of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

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Humayun Bashir Departments of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

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M. Khalid Nawaz Departments of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

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Raza Hussain Departments of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

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Introduction Differentiated thyroid cancer (DTC) is typically indolent if treated early and appropriately. A small subset of more aggressive disease progresses to radioiodine resistance. Based on the American Thyroid Association (ATA) risk of

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Guo-Qiang Zhang Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Chen-Tian Shen Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Hong-Jun Song Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Zhong-Ling Qiu Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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Quan-Yong Luo Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

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and the rapid advances in diagnostic radiology tools [ 2 ]. Thyroid cancer is characterized by different clinicopathological properties, and differentiated thyroid cancer (DTC) accounts for more than 90% of thyroid cancer cases [ 3 ]. Although patients

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Fabián Pitoia Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Fernando Jerkovich Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Anabella Smulever Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Gabriela Brenta Division of Endocrinology, Dr. César Milstein Hospital, Buenos Aires, Argentina

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Fernanda Bueno Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Graciela Cross Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires

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Introduction Various staging systems have historically been used to assess the risk of mortality in patients with differentiated thyroid cancer (DTC) [ 1 , 2 , 3 , 4 , 5 ]. All of them are strongly dependent on patient age since age at

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Cláudia C.D. Nakabashi Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Teresa S. Kasamatsu Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Felipe Crispim Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Claudia A. Yamazaki Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Cléber P. Camacho Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Danielle M. Andreoni Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Rosalia P. Padovani Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Elza S. Ikejiri Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Maria C.O.M. Mamone Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Flávia C. Aldighieri Fleury Medicina e Saúde, São Paulo, Brazil

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Jairo Wagner Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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Jairo T. Hidal Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil

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José G.H. Vieira Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicina e Saúde, São Paulo, Brazil

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Rosa P.M. Biscolla Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Rui M.B. Maciel Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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M, Sherman SI, Steward D, Tuttle RM: Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19:1-48. 10.1089/thy.2009.0110 19860577 6 Tuttle RM: Risk

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Juan J. Lence-Anta Institute of Oncology and Radiobiology, Havana, Cuba

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Constance Xhaard Radiation Epidemiology Group, 1018 INSERM Unit, Havana, Cuba
Institut Gustave Roussy, Havana, Cuba
University Paris-Sud, Villejuif, France

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Rosa M. Ortiz Institute of Oncology and Radiobiology, Havana, Cuba

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Haoiinda Kassim Radiation Epidemiology Group, 1018 INSERM Unit, Havana, Cuba
Institut Gustave Roussy, Havana, Cuba
University Paris-Sud, Villejuif, France

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Celia M. Pereda Institute of Oncology and Radiobiology, Havana, Cuba

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Silvia Turcios National Institute of Endocrinology, Havana, Cuba

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Milagros Velasco Institute of Oncology and Radiobiology, Havana, Cuba

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Mae Chappe Institute of Oncology and Radiobiology, Havana, Cuba

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Idalmis Infante Institute of Oncology and Radiobiology, Havana, Cuba

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Marlene Bustillo Institute of Oncology and Radiobiology, Havana, Cuba

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Anabel García Institute of Oncology and Radiobiology, Havana, Cuba

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Enora Clero Radiation Epidemiology Group, 1018 INSERM Unit, Havana, Cuba
Institut Gustave Roussy, Havana, Cuba
University Paris-Sud, Villejuif, France

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Stephane Maillard Radiation Epidemiology Group, 1018 INSERM Unit, Havana, Cuba
Institut Gustave Roussy, Havana, Cuba
University Paris-Sud, Villejuif, France

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Sirced Salazar Institute of Oncology and Radiobiology, Havana, Cuba

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Regla Rodriguez Cuban Health Public Ministry, Havana, Cuba

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Florent de Vathaire Radiation Epidemiology Group, 1018 INSERM Unit, Havana, Cuba
Institut Gustave Roussy, Havana, Cuba
University Paris-Sud, Villejuif, France

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French Polynesia of body mass index and differentiated thyroid cancer: the importance of body surface area. Thyroid 2010;20:1285-1293. 10.1089/thy.2009.0456 20932181 11 Peterson E, De P, Nuttall R: BMI, diet and female reproductive factors as

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Nicholas S. Andresen Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Buatti Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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Hamed H. Tewfik Iowa City Cancer Treatment Center, Iowa City, Iowa, USA

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Nitin A. Pagedar Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, USA

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Carryn M. Anderson Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Watkins Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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Introduction Thyroid cancer is the most frequently occurring endocrine cancer, with an increasing incidence noted in the US over the past 15 years [ 1 ]. Papillary and follicular histologic subtypes, known as “differentiated thyroid cancers

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Germán A. Jimenez Londoño Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Ana Maria Garcia Vicente Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Julia Sastre Marcos Department of Endocrinology, Complejo Hospitalario de Toledo, Toledo, Spain

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Francisco Jose Pena Pardo Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Mariano Amo-Salas Department of Mathematics, University of Castilla-La Mancha, Ciudad Real, Spain

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Manuel Moreno Caballero Department of Nuclear Medicine, Hospital Universitario Infanta Cristina Badajoz, Badajoz, Spain

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Maria Prado Talavera Rubio  Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Beatriz Gonzalez Garcia Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Niletys Dafne Disotuar Ruiz Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Angel Maria Soriano Castrejón Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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low-risk differentiated thyroid cancer (LRDTC) and second, to assess the influence of clinical factors in the therapeutic response. Methods A longitudinal and multicentre study, including 5 hospitals, was performed in accordance with the

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Constance Xhaard U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Juan J. Lence-Anta National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Yan Ren U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Françoise Borson-Chazot Groupement Hospitalier Lyon-Est, Hospices Civils de Lyon, Fédération d'Endocrinologie, Bron
Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon

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Geneviève Sassolas Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon

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Claire Schvartz Thyroid Cancer Registry of Champagne-Ardennes, Institut Jean Godinot, Reims

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Marc Colonna Cancer Registry of Isère, Meylan

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Brigitte Lacour Institut Gustave Roussy, Villejuif, France
French National Registry of Childhood Solid Tumours, CHU, Nancy

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Arlette Danzon Cancer Registry of Doubs, EA 3181, Université de Franche-Comté, Besançon

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Michel Velten Cancer Registry of Bas-Rhin, EA 3430, Faculty of Medicine, University of Strasbourg, Strasbourg

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Enora Clero U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Stéphane Maillard U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Emilie Marrer Cancer Registry of Haut-Rhin, Mulhouse Hospital, Mulhouse

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Laurent Bailly Public Health Department, University Hospital Nice, Nice

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Eugènia Mariné Barjoan Public Health Department, University Hospital Nice, Nice

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Martin Schlumberger Institut Gustave Roussy, Villejuif, France

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Jacques Orgiazzi Department of Endocrinology, Hospices Civils de Lyon, Lyon, France

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Elisabeth Adjadj U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Université Paris-Saclay, Villejuif, France

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Celia M. Pereda National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Silvia Turcios National Institute of Endocrinology, Cuba

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Milagros Velasco National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Mae Chappe National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Idalmis Infante National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Marlene Bustillo National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Anabel García National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Sirced Salazar National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Regla Rodriguez Cuban Public Health Ministry, Havana, Cuba

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Mohamed Amine Benadjaoud U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Rosa M. Ortiz National Institute of Oncology and Radiobiology (INOR), Havana, Cuba

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Carole Rubino U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Florent de Vathaire U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France

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Introduction Over the last few decades, the differentiated thyroid cancer (DTC) incidence has grown rapidly in many countries [ 1 ]. The study of DTC risk factors is therefore of great importance to understand this observed increase in

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