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Ralf Paschke
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Silvia Cantara
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Anna Crescenzi
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Barbara Jarzab
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Thomas J. Musholt
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Manuel Sobrinho Simoes
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thyroid cytology. Endocr Pract 2014;20: 364–369. 10.4158/EP13330.OR 24246351 31 Lastra RR, Pramick MR, Crammer CJ, LiVolsi VA, Baloch ZW: Implications of a suspicious afirma test result in thyroid fine-needle aspiration cytology: an institutional

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Mario Rotondi Unit of Internal Medicine and Endocrinology, Fondazione Salvatore Maugeri I.R.C.C.S., ISPESL Laboratory for Endocrine Disruptors and Chair of Endocrinology, University of Pavia, Pavia

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Maria Grazia Castagna Departments of Medical, Surgical and Neurological Sciences, Siena

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Carlo Cappelli Department of Medical and Surgical Sciences, University of Brescia, Brescia, Italy

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Cristina Ciuoli Departments of Medical, Surgical and Neurological Sciences, Siena

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Francesca Coperchini Unit of Internal Medicine and Endocrinology, Fondazione Salvatore Maugeri I.R.C.C.S., ISPESL Laboratory for Endocrine Disruptors and Chair of Endocrinology, University of Pavia, Pavia

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Francesco Chiofalo Departments of Medical, Surgical and Neurological Sciences, Siena

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Fabio Maino Departments of Medical, Surgical and Neurological Sciences, Siena

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Paola Palmitesta Departments of Social, Political and Cognitive Sciences, University of Siena, Siena

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Luca Chiovato Unit of Internal Medicine and Endocrinology, Fondazione Salvatore Maugeri I.R.C.C.S., ISPESL Laboratory for Endocrine Disruptors and Chair of Endocrinology, University of Pavia, Pavia

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Furio Pacini Departments of Medical, Surgical and Neurological Sciences, Siena

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subjected to fine-needle aspiration cytology (FNAC) and stratified according to their BMI. This selection approach should theoretically avoid the above-reported bias as well as the bias connected to surgical series where the criteria for surgery may not be

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Pedro Weslley Souza Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Meenu Gill Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak

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Ashima Batra Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak

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Ashok Sangwaiya Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak

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Samta Shakya General Hospital, Sirsa, India

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Sumiti Gupta Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak

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Rajeev Sen Department of Pathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak

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Primary thyroid gland lymphomas (PTLs) typically occur in middle- to older-aged individuals in the setting of lymphocytic thyroiditis with a predilection for females. Diffuse large B-cell lymphoma is the most frequent histologic subtype of thyroid lymphomas. Small lymphocytic lymphoma (SLL) belongs to the least common subtypes of thyroid lymphoma. It is often associated with the involvement of lymph nodes, bone marrow, spleen, liver and, extremely rarely, other organs. PTLs with plasmacytic differentiation or extensive infiltration by plasma cells have been observed in marginal zone B-cell lymphomas in the thyroid but have never been described in a setting of SLL. Here, we present a case of primary SLL of the thyroid mimicking extramedullary plasmacytoma on fine-needle aspiration cytology.

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Maria Mavromati Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Verdiana Caironi Department of Internal Medicine, Lugano Regional Hospital, Ente Ospedaliero Cantonale, Via Tesserete Lugano, Switzerland

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Essia Saiji Department of Pathology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Maria-Isabel Vargas Department of Neuroradiology, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Shahan Momjian Department of Neurosurgery, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Stephanie Andrade-Lopes Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Capucine Gubert Department of Internal Medicine, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Marco Stefano Demarchi Department of Thoracic and Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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Ismini Mainta Department of Nuclear Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland

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François R Jornayvaz Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Kaveh Samii Department of Hematology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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Grégoire Stalder Service and Central Laboratory of Hematology, Lausanne University Hospital, rue du Bugnon Lausanne, Switzerland.
Service of Hematology and Laboratory of Hematology, Institut Central des Hôpitaux, Hôpital du Valais, Av. du Grand-Champsec, Sion, Switzerland

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Sophie Leboulleux Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, Geneva, Switzerland
University of Geneva, Faculty of Medicine, Rue Michel Servet, Geneva, Switzerland

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, 3 , 4 , 5 , 6 , 7 ). Thyroid ultrasound-guided fine needle aspiration cytology (FNAC) can be a noninvasive and useful tool to confirm the diagnosis and prevent unnecessary transcranial biopsy ( 3 , 8 ). Here we present the case of a young

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Chitra Choudhary Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Leonard Wartofsky Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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Eshetu Tefera MedStar Health Research Institute, Washington, D.C., USA

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Kenneth D. Burman Department of Endocrinology, Medstar Washington Hospital Center, Washington, D.C., USA

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sonographic findings, and fine-needle aspiration cytology is sometimes indicated to determine the histology [ 5 ]. Sonographic findings and Tg levels can help in identifying high-risk patients for whom fine-needle aspiration cytology will be definitely

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Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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beginning of a vascular encasement. USG-guided fine-needle aspiration cytology (FNAC) was performed on the nodule of greatest size [ 9 ]. FNAC was consistent with ‘suspicious for a follicular neoplasm’ according to the Bethesda system [ 10 ]. Due to the

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Maria Mavromati Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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Essia Saiji Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Marco Stefano Demarchi Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Vincent Lenoir Department of Radiology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Amanda Seipel Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Paulina Kuczma Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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François R Jornayvaz Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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Minerva Becker Department of Radiology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Eugenio Fernandez Department of Oncology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Claudio De Vito Department of Pathology, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Frédéric Triponez Department of Endocrine Surgery, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva, Switzerland

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Sophie Leboulleux Department of Endocrinology, Diabetology, Nutrition and Therapeutic Education, Geneva University Hospitals, Rue Gabrielle Perret Gentil, Geneva University, Geneva, Switzerland

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with surgery, active surveillance, or local treatment, depending on the size of the nodule ( 3 , 4 , 5 , 6 ). Given the high rate of thyroid nodules, most of which are benign, to reduce fine needle aspiration cytology (FNAC) and unnecessary surgery

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José I. López Department of Pathology, Cruces University Hospital, BioCruces Research Institute, University of the Basque Country, Barakaldo

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Rosa Zabala Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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José Luís del Cura Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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sensitivity and specificity of the technique [ 4 ], and makes it possible to take samples of the solid areas in cystic lesions. Despite fine-needle aspiration cytology (FNAC) being almost universally used to take thyroid samples and, accordingly, there being

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Eun Kyung Jang Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Dong Eun Song Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Gyungyub Gong Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Jung Hwan Baek Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

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Yun Mi Choi Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Min Ji Jeon Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Ji Min Han Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Gu Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Tae Yong Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Young Kee Shong Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Bae Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Kitano M, Sugitani I, Toda K, Ikenaga M, Motoi N, Yamamoto N, Hotomi M, Fujimoto Y, Kawabata K: Cytopathological review of patients that underwent thyroidectomies based on the diagnosis of papillary thyroid carcinoma by fine needle aspiration cytology but

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