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Mats Holmberg ANOVA, Karolinska University Hospital, Norra Stationsgatan 69, Stockholm, Sweden
Institute of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden
Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden

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Helge Malmgren Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Peter F Berglund Institute of Neuroscience and Physiology, Department of Clinical Neuroscience, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Birgitta Johansson Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Helena Filipsson Nyström Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden
Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden
Gothenburg Centre for Person Centred-Care (GPCC), Göteborg, Sweden

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mental symptoms may be a consequence of the elevated thyroid hormones, the autoimmune reaction, the circumstance that persons with psychiatric conditions may be more prone to develop Graves’ disease (GD), the development of complications like thyroid

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-23-0247
Volume/Issue:
Volume 13: Issue 1
Open access
N. Papanikolaou Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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P. Perros Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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thyrotoxicosis and resolves rapidly after euthyroidism is restored. • Awareness of this very rare manifestation of thyrotoxicosis may obviate the need to seek alternative diagnoses. Introduction Graves’ disease is the commonest cause of thyrotoxicosis

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000343826
Volume/Issue:
Volume 1: Issue 4
Free access
Shi Hui Junice Wong Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore

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Established Facts Radioiodine (RAI) therapy for Graves’ disease is generally well tolerated. RAI therapy can rarely cause radiation-induced thyroiditis, but this is self-limiting and localized to the thyroid gland. Novel

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000503457
Volume/Issue:
Volume 8: Issue 6
Free access
Kira Bang Bové Department of Endocrinology, Odense, Denmark

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Torquil Watt Department of Endocrinology, Odense, Denmark
Institute of Public Health, University of Copenhagen, Odense, Denmark

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Asmus Vogel Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Jakob Bue Bjoerner Institute of Public Health, University of Copenhagen, Odense, Denmark
National Research Centre for the Working Environment, Copenhagen, Odense, Denmark

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Mogens Groenvold Institute of Public Health, University of Copenhagen, Odense, Denmark
Department of Palliative Medicine, Bispebjerg Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Åse Krogh Rasmussen Department of Endocrinology, Odense, Denmark

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Ulla Feldt-Rasmussen Department of Endocrinology, Odense, Denmark

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depression [ 2 , 3 , 4 , 5 , 6 ] but increased prevalence of anxiety and depression is also found in hyperthyroidism [ 7 ], particularly in the early phase of Graves' disease [ 8 , 9 , 10 , 11 ], compared with the general population or compared with patients

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000365211
Volume/Issue:
Volume 3: Issue 3
Free access
Marta Nascimento Soares Faculty of Medicine of the University of Porto, Porto, Portugal

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Marta Borges-Canha Faculty of Medicine of the University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal

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Celestino Neves Faculty of Medicine of the University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal

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João Sérgio Neves Faculty of Medicine of the University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal

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Davide Carvalho Faculty of Medicine of the University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal

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Introduction Graves' disease is an autoimmune thyroid disease, being the most frequent cause of hyperthyroidism ( 1 ). It is caused by the production of autoantibodies (thyrotropin receptor antibodies (TRAbs)) against the thyrotropin receptor

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-23-0055
Volume/Issue:
Volume 12: Issue 4
Open access
Alessandro Brancatella Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Nicola Viola Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Sandra Brogioni Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Lucia Montanelli Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Chiara Sardella Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Isabella Lupi Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Francesco Latrofa Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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contrary, Graves’ disease has been described in only eight patients during ICPis treatment, five during anti-CTLA-4 and three during anti-PD-1 treatment. We report the fourth case of Grave’s disease induced by anti-PD-1, the second with an overt

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000501824
Volume/Issue:
Volume 8: Issue 4
Free access
Cosimo Rodia Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Francesca Menconi Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Laura Mazoni Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Liborio Torregrossa Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Michele Marinò Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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What Is Known about this Topic? Thyroid dermopathy is a rare extrathyroidal manifestation of Graves’ disease (GD). It is usually bilateral, but monolateral variants can be observed. As for Graves’ orbitopathy, the most common

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000500297
Volume/Issue:
Volume 8: Issue 5
Free access
Ringo Manta Department of Nuclear Medicine, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Charlotte Martin Department of Infectious Diseases, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Vinciane Muls Department of Gastroenterology and Endoscopy, CHU Saint-Pierre, University Libre de Bruxelles (ULB), Brussels, Belgium

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Kris G Poppe Department of Endocrinology, CHU Saint Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Established facts SARS-CoV-2 can be complicated by different types of autoimmune thyroiditis. Few cases of Graves’ disease (GD) following SARS-CoV-2 (vaccination) have been reported. Novel insights A previous episode

Article Type:
Case Report
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0049
Volume/Issue:
Volume 11: Issue 4
Open access
Hirotoshi Nakamura Kuma Hospital, Kobe, Japan

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Akane Ide Kuma Hospital, Kobe, Japan

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Takumi Kudo Kuma Hospital, Kobe, Japan

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Eijun Nishihara Kuma Hospital, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Kobe, Japan

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Introduction Agranulocytosis (AG) is one of the most serious complications of antithyroid drug (ATD) therapy for Graves' disease. It is rare, but if its discovery is delayed and severe infection develops, a lethal outcome can happen [ 1 ]. In

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000448586
Volume/Issue:
Volume 5: Issue 4
Open access
Caiyan Mo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Han Chen Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Qi Zhang Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Ying Guo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Liyong Zhong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Introduction Graves' disease (GD) is an autoimmune disease of the thyroid gland and is the most common cause of hyperthyroidism. The annual incidence is 20–50 cases per 100,000 people, with a peak incidence between the ages of 30 and 50. The

Article Type:
Review Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0223
Volume/Issue:
Volume 12: Issue 4
Open access