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[ 5 ], lithium [ 6 ], bexarotene [ 7 ], immune checkpoint inhibitors [ 8 ], and thyrosine kinases inhibitors [ 9 , 10 ]. The present guidelines will focus on thyroid autoimmunity (TA) induced by immune reconstitution therapy (IRT), characterized by a
Endocrinology Unit, Graves’ Orbitopathy Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Ophthalmology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Department of Specialistic Surgical Sciences, Otolaryngology and Head and Neck Surgery, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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relapsing–remitting multiple sclerosis (MS). It causes panlymphopenia followed by lymphocyte repopulation, thus classified as an immune reconstitution therapy (IRT) ( 1 , 2 ). After ALTZ, 34–41% of patients with MS develop thyroid autoimmunity, in 63–65% of
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in an AIDS patient can be attributed to a number of processes including Graves' disease in the setting of the immune reconstitution syndrome, various antiretroviral drugs and complicating infections, such as cytomegalovirus. The absence of tracer
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non-lactating women. 1, ∅∅○○ 43 MMI is recommended during lactation, given the concerns about PTU-mediated hepatotoxicity. 1, ∅∅○○ The Elderly, Children and Adolescents, and Immune Reconstitution Elderly Although the incidence of GD
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disease . American Journal of Medicine 2010 123 183.e1 – 183.e9 . ( https://doi.org/10.1016/j.amjmed.2009.06.030 ) 19 Sinha A Abinun M Gennery AR Barge D Slatter M Cheetham T . Graves’ immune reconstitution inflammatory syndrome in