Tumay Ozgur
Tumay Ozgur
Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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Hasan Gokce
Hasan Gokce
Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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Ihsan Ustun
Ihsan Ustun
Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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Mehmet Yaldiz
Mehmet Yaldiz
Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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Mehmet Mustafa Akin
Mehmet Mustafa Akin
Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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Cumali Gokce
Cumali Gokce
Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey
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. What This Case Report Adds • An unusual case of Riedel thyroiditis in a patient with asymptomatic multinodular goiter and thyroid autoantibodies. • The true nature of thyroid pathology in this case was suggested by ultrasonography (not by fine
Mafalda Marcelino
Mafalda Marcelino
Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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Pedro Marques
Pedro Marques
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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Luis Lopes
Luis Lopes
Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal
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Valeriano Leite
Valeriano Leite
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal
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João Jácome de Castro
João Jácome de Castro
Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal
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]. Larger and prospective studies are required to evaluate this issue. Moreover, there are some data reporting unusual toxic thyroid carcinomas [ 9 ], and recent studies suggest that the frequency of malignancy in toxic multinodular goiter (TMNG) is
Rui Guo
Rui Guo
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Bowen Zheng
Bowen Zheng
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Tao Wu
Tao Wu
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Yufan Lian
Yufan Lian
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Tinghui Yin
Tinghui Yin
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Yuting He
Yuting He
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Jingya Qin
Jingya Qin
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Zhicheng Yao
Zhicheng Yao
Department of General Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Wen Xu
Wen Xu
Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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Jie Ren
Jie Ren
Department of Medical Ultrasonics, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Province Key Laboratory of Hepatology Research, Guangzhou, Guangdong, People’s Republic of China
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criteria, 29 patients were excluded due to their previous history of thyroid surgery or radioactive iodine treatment. Ultimately, 185 patients were included ( Fig. 2 ). Figure 2 Flowchart of the retrospective study. MNG, multinodular goiter; RFA
Hippolyte Dupuis
Hippolyte Dupuis
Department of Endocrinology, Diabetology and Metabolism, Huriez Hospital, Lille University Hospital, Lille, France
University of Lille, Lille, France
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University of Lille, Lille, France
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Emilie Merlen
Emilie Merlen
Department of Endocrinology, Diabetology and Metabolism, Huriez Hospital, Lille University Hospital, Lille, France
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Arnaud Jannin
Arnaud Jannin
Department of Endocrinology, Diabetology and Metabolism, Huriez Hospital, Lille University Hospital, Lille, France
University of Lille, Lille, France
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University of Lille, Lille, France
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Philippe Jamme
Philippe Jamme
University of Lille, Lille, France
Department of Dermatology, Lille University Hospital, Lille, France
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Department of Dermatology, Lille University Hospital, Lille, France
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Alexandre Fagart
Alexandre Fagart
Department of Nuclear Medicine, Valenciennes Hospital Center, Valenciennes, France
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Marie-Christine Vantyghem
Marie-Christine Vantyghem
Department of Endocrinology, Diabetology and Metabolism, Huriez Hospital, Lille University Hospital, Lille, France
University of Lille, Lille, France
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University of Lille, Lille, France
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Miriam Ladsous
Miriam Ladsous
Department of Endocrinology, Diabetology and Metabolism, Huriez Hospital, Lille University Hospital, Lille, France
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) examination revealed a 51.6 mL multinodular goiter (MNG) with three main nodules in the right lobe (one 15 mm EU-TIRADS III nodule and two EU-TIRADS IV micronodules) and two nodules in the left lobe (25 mm EU-TIRADS V in the middle part and 33 mm EU-TIRADS III
Nooshin Zargari
Nooshin Zargari
Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran
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Maral Mokhtari
Maral Mokhtari
Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran
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architecture and PTC nuclear features, no invasion (capsular or vascular), solid component < 30%, mitotic count of < 3/10 high power field, and no necrosis; as multinodular goiter (MNG) if showing huge follicles lined by flattened epithelium; as Hurthle cell
Lucia Russo
Lucia Russo
Department of Medicine, DIMED, Internal Medicine 3, University of Padua, Padova, Italy
Department of Endocrinology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Department of Endocrinology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Thi Ngoc Huyen Nguyen
Thi Ngoc Huyen Nguyen
Department of Endocrinology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Aglaia Kyrilli
Aglaia Kyrilli
Department of Endocrinology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Martin Robin
Martin Robin
Department of Nuclear Medicine, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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Pierre Bel Lassen
Pierre Bel Lassen
Department of Urology, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium
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Rodrigo Moreno-Reyes
Rodrigo Moreno-Reyes
UMRS 1166 (Inserm), Paris, France
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Bernard Corvilain
Bernard Corvilain
Department of Endocrinology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
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following the correction of eSCH due to multinodular goiter by another therapeutic modality, radioactive iodine ( 131 I). In the absence of a euthyroid control group treated by 131 I, we compared patients with grade 1 eSCH and grade 2 eSCH to investigate
Tomasz Bednarczuk
Tomasz Bednarczuk
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland
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Thomas H. Brix
Thomas H. Brix
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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Wolfgang Schima
Wolfgang Schima
Department of Diagnostic and Interventional Radiology, Goettlicher Heiland Krankenhaus, Barmherzige Schwestern Krankenhaus, and Sankt Josef Krankenhaus, Vienna, Austria
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Georg Zettinig
Georg Zettinig
Schilddruesenpraxis Josefstadt, Vienna, Austria
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George J. Kahaly
George J. Kahaly
Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, Germany
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previously asymptomatic multinodular goiter. Nowadays, elderly patients are more often exposed to radiological studies using ICM than in the past because of major technological advances and increased longevity. Hyper in the elderly is more likely
Mohamed E. Ahmed
Mohamed E. Ahmed
Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan
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Departments of Medicine, Khartoum, Sudan
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Mohamed A. Mahgoub
Mohamed A. Mahgoub
Khartoum Teaching Hospital, Khartoum, Sudan
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Mohamed G. Alnedar
Mohamed G. Alnedar
Khartoum Teaching Hospital, Khartoum, Sudan
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Seif I. Mahadi
Seif I. Mahadi
Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan
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Departments of Medicine, Khartoum, Sudan
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Maha Alzubeir
Maha Alzubeir
Surgery, Faculty of Medicine, Khartoum, Sudan
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Lamyaa A.M. El Hassan
Lamyaa A.M. El Hassan
University of Ahfad, Khartoum, Sudan
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ElWaleed M. Elamin
ElWaleed M. Elamin
Alzaeim Alazhari University, Khartoum, Sudan
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Ahmed Mohammed El Hassan
Ahmed Mohammed El Hassan
University of Khartoum, Khartoum, Sudan
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solids. Upper gastrointestinal endoscopy was normal. There was some degree of ptosis that was detected retrospectively after the final diagnosis was made. General examination was unremarkable. Cervical examination showed a simple multinodular goiter
Thomas Szabo Yamashita
Thomas Szabo Yamashita
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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Fady J. Baky
Fady J. Baky
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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Travis J. McKenzie
Travis J. McKenzie
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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Geoffrey B. Thompson
Geoffrey B. Thompson
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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David R. Farley
David R. Farley
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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Melanie L. Lyden
Melanie L. Lyden
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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Benzon M. Dy
Benzon M. Dy
Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
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. Preoperative ultrasound showed that 83% of patients who underwent thyroidectomy had multinodular goiter, with a minority presenting solitary nodules. There were 9 (19%) patients diagnosed with thyroid cancer at a mean age of 28.5 years (16–41 years) and all
Marek Niedziela
Marek Niedziela
Department of Pediatric Endocrinology and Rheumatology, Poznan University of Medical Sciences, Poznan, Poland
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Nelly Sabbaghian
Nelly Sabbaghian
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
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Leanne de Kock
Leanne de Kock
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada
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Department of Human Genetics, McGill University, Montreal, Québec, Canada
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William D. Foulkes
William D. Foulkes
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada
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Department of Human Genetics, McGill University, Montreal, Québec, Canada
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a similar ultrasonographic pattern to papillary thyroid carcinoma should be considered in the differential diagnosis of an apparent thyroid nodule [ 1 , 2 ]. Thyroid disease, particularly multinodular goiter (MNG), is the most frequent feature
