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Hao Li Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otorhinolaryngology, Tan Tock Seng Hospital, Singapore, Singapore

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Nir Livneh Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Ramat Gan, Israel

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Snjezana Dogan Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Ashok R. Shaha Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Introduction Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are thyroid neoplasms derived from different cell types. While the former is common, the latter is much less frequent [ 1 , 2 ]. The synchronous occurrence

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000511184
Volume/Issue:
Volume 10: Issue 4
Free access
Pedro Marques Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Maria João Bugalho Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Introduction Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. The widespread use of neck ultrasound (US) has led to the identification of small asymptomatic thyroid nodules with indeterminate clinical relevance [ 1

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000369133
Volume/Issue:
Volume 3: Issue 4
Free access
Sule Canberk Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal

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Joana C. Ferreira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Luísa Pereira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Rui Batısta Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Andre F. Vieira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Manuel Sobrinho Simões Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
Department of Pathology and Oncology, Centro Hospitalar São João, Porto, Portugal

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Valdemar Máximo Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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well-established driver mutations [ 1 , 2 ]. Papillary thyroid carcinoma (PTC), the most common type (i.e., 90% of all thyroid malignancies) probably contributes to most such tumours in this “dark zone” [ 3 ]. Approximately 90% of thyroid cancers

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000509183
Volume/Issue:
Volume 9: Issue 6
Free access
Eun Kyung Jang Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Dong Eun Song Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Gyungyub Gong Departments of Pathology, University of Ulsan College of Medicine, Seoul, South Korea

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Jung Hwan Baek Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

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Yun Mi Choi Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Min Ji Jeon Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Ji Min Han Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Gu Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Tae Yong Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Young Kee Shong Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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Won Bae Kim Departments of Internal Medicine, University of Ulsan College of Medicine, Seoul, South Korea

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-10% [ 3 , 4 , 5 ]. It is very rare to have a result of no evidence of malignancy by histological evaluation of the thyroid in patients with a preoperative cytological diagnosis of papillary thyroid carcinoma (PTC) [ 6 , 7 ]. One report noted disappearing

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000353624
Volume/Issue:
Volume 2: Issue 3
Free access
Akira Miyauchi Departments of Surgery, Kuma Hospital, Kobe, Japan

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Takumi Kudo Departments of Internal Medicine, Kuma Hospital, Kobe, Japan

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Mitsuyoshi Hirokawa Departments of Pathology, Kuma Hospital, Kobe, Japan

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Yasuhiro Ito Departments of Surgery, Kuma Hospital, Kobe, Japan

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Minoru Kihara Departments of Surgery, Kuma Hospital, Kobe, Japan

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Takuya Higashiyama Departments of Surgery, Kuma Hospital, Kobe, Japan

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Tomonori Yabuta Departments of Surgery, Kuma Hospital, Kobe, Japan

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Hiroo Masuoka Departments of Surgery, Kuma Hospital, Kobe, Japan

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Hisakazu Shindo Departments of Surgery, Kuma Hospital, Kobe, Japan

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Kaoru Kobayashi Departments of Surgery, Kuma Hospital, Kobe, Japan

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Akihiro Miya Departments of Surgery, Kuma Hospital, Kobe, Japan

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Introduction Thyroid cancer is the most common malignancy in the endocrine organs. Papillary thyroid carcinoma is the representative pathological type, constituting about 90% of thyroid cancers. Papillary carcinoma generally shows an indolent

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000347148
Volume/Issue:
Volume 2: Issue 1
Free access
Pedro Weslley Rosario Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Gabriela Franco Mourão Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Maria Regina Calsolari Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

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Introduction Ultrasonography (US) is a widely available, noninvasive, and sensitive technique for the detection of locoregional disease in patients operated on for papillary thyroid carcinoma (PTC). After ablation or adjuvant therapy with

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000493978
Volume/Issue:
Volume 8: Issue 1
Free access
Kaoru Kobayashi Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuyoshi Hirokawa Kuma Hospital, Kobe City, Hyogo, Japan

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Tomonori Yabuta Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuhiro Fukushima Kuma Hospital, Kobe City, Hyogo, Japan

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Minoru Kihara Kuma Hospital, Kobe City, Hyogo, Japan

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Yuuki Takamura Kuma Hospital, Kobe City, Hyogo, Japan

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Yasuhiro Ito Kuma Hospital, Kobe City, Hyogo, Japan

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Akihiro Miya Kuma Hospital, Kobe City, Hyogo, Japan

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Nobuyuki Amino Kuma Hospital, Kobe City, Hyogo, Japan

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Akira Miyauchi Kuma Hospital, Kobe City, Hyogo, Japan

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patients with honeycomb-like papillary thyroid carcinoma showing multiple small cysts, and describe the characteristic features on ultrasonography. Methods and Patients Ultrasonographic examination was performed by well-trained registered

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000353780
Volume/Issue:
Volume 2: Issue 4
Free access
Ian D Hay Department of Medicine 1, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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Suneetha Kaggal Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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Geoffrey B Thompson Department of Surgery, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA

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Introduction Adults with low-risk ( 1 ) papillary thyroid carcinoma (PTC) represent the commonest endocrine malignancy ( 2 ). In 2017, Pontius and colleagues ( 3 ) demonstrated, in a study of 244,040 PTC patients managed in USA during 2004

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-22-0084
Volume/Issue:
Volume 11: Issue 4
Open access
Adile Begüm Bahçecioğlu Department of Endocrinology and Metabolism, Ankara University, School of Medicine, Ankara, Turkey

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Alptekin Gürsoy Department of Endocrinology and Metabolism, Ankara Guven Hospital, Ankara, Turkey

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Serpil Dizbay Sak Department of Pathology, Ankara University, School of Medicine Ankara, Turkey

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Seyfettin Ilgan Department of Nuclear Medicine, Ankara Guven Hospital, Ankara, Turkey

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Banu Bilezikçi Department of Pathology, Ankara Guven Hospital, Ankara, Turkey

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Murat Faik Erdoğan Department of Endocrinology and Metabolism, Ankara University, School of Medicine, Ankara, Turkey

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Introduction Ultrasonographic (US) echogenic microfoci (EMF) are frequently seen in papillary thyroid carcinoma (PTC). European Thyroid Association, the American College of Radiology (ACR), and the Korean Society of Thyroid Radiology classify

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0108
Volume/Issue:
Volume 12: Issue 6
Open access
Shinsuke Shinkai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kenji Ohba Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kennichi Kakudo Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Osaka, Japan

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Takayuki Iwaki Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yoshihiro Mimura Department of Internal Medicine, American Hospital of Paris, Neuilly sur Seine, France

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Akio Matsushita Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Go Kuroda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yuki Sakai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Nobuhiko Nishino Department of Surgery, Maruyama Hospital, Shizuoka, Japan

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Kazuo Umemura Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan
Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Shigekazu Sasaki Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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common somatic mutation in papillary thyroid carcinoma). What Does This Case Report Add? • We identified concurrent BRAF mutation and TSHR polymorphism for the first time in a case of hyperfunctioning malignant thyroid nodule. • The findings

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000513552
Volume/Issue:
Volume 10: Issue 3
Free access