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Stine Linding Andersen and Peter Laurberg

[ 2 ], and this may well lead to inadequate iodine intake among pregnant women because there is an increase in the need for iodine during pregnancy [ 3 , 4 ]. Thus, in recent years there has been much focus on the potential need for individual intake

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Peter Taylor, Sandip Bhatt, Ravi Gouni, Jonathan Quinlan, and Tony Robinson

What Is Known about This Topic • The prevalence of hyperthyroidism in pregnancy has been estimated to range between 0.1 and 1% [ 1 , 2 , 3 , 4 , 5 ] and if untreated or poorly treated there is an increased risk of adverse outcomes including

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Sara Donato, Helder Simões, and Valeriano Leite

than differentiated thyroid cancer; There are scarce data about malignant SO evolution during pregnancy. Novel Insight Pregnancy may represent a stimulus for malignant SO growth in patients with previous biochemical evidence of

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Suvi Turunen, Marja Vääräsmäki, Maarit Leinonen, Mika Gissler, Tuija Männistö, and Eila Suvanto

Introduction Thyroid dysfunction affects up to 5–7% of all pregnancies [ 1 ]. Hypothyroidism in pregnant women is common with a prevalence of about 2-3%, and the prevalence of undiagnosed subclinical hypothyroidism in pregnancy is 3–15% [ 2

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Françoise Brucker-Davis, Patricia Panaïa-Ferrari, Jocelyn Gal, Patrick Fénichel, and Sylvie Hiéronimus

Introduction The thyroid hormone economy changes profoundly during pregnancy to accommodate maternal and fetal needs [ 1 ]. The main factors involved are the βHCG secretion by the placenta (with its stimulatory effect on maternal thyroid), the

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Kris Poppe, Alicja Hubalewska-Dydejczyk, Peter Laurberg, Roberto Negro, Francesco Vermiglio, and Bijay Vaidya

Introduction The prevalence of hyperthyroidism in pregnancy ranges between 0.1 and 1% [ 1 ]. The most common cause of hyperthyroidism in pregnancy is Graves’ disease (GD), occurring in about 85% of cases. Gestational transient thyrotoxicosis

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Roberto Negro, Roberto Attanasio, Enrico Papini, Rinaldo Guglielmi, Franco Grimaldi, Vincenzo Toscano, Dan Alexandru  Niculescu, Diana Loreta  Paun, and Catalina Poiana

Introduction An increasing number of studies focusing on thyroid disease and pregnancy have been published over the last decades. Such interest has been driven by at least 2 factors: the relevant number of women suffering from thyroid disease

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John Lazarus, Rosalind S. Brown, Chantal Daumerie, Alicja Hubalewska-Dydejczyk, Roberto Negro, and Bijay Vaidya

Introduction Subclinical hypothyroidism (SCH) in pregnancy is defined by a serum thyroid-stimulating hormone (TSH) concentration higher than the upper limit of the pregnancy-related reference range associated with a normal serum thyroxine [T 4

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Stine Linding Andersen, Louise Kolding Sørensen, Anne Krejbjerg, Margrethe Møller, and Peter Laurberg

Introduction Population median urinary iodine concentration (UIC) is the recommended method to assess iodine status [ 1 ]. UIC in pregnancy is extensively studied and adequate maternal iodine intake is of major concern [ 2 , 3 , 4

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Peter N. Taylor and Bijay Vaidya

Introduction Hyperthyroidism in pregnancy is a serious condition, resulting in increased risk of adverse obstetric outcomes including miscarriage, stillbirth, pre-term birth and intra-uterine growth restriction [ 1 ]. Its management is complex