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Bertrand Volard Departments of Biopathology, Centre François Baclesse, Caen, France

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Sophie Krieger EA 1772, University of Basse-Normandie, Centre François Baclesse, Caen, France
Departments of Biopathology, Centre François Baclesse, Caen, France

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Gaétane Planchard Departments of Biopathology, Centre François Baclesse, Caen, France

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Agnès Hardouin Departments of Biopathology, Centre François Baclesse, Caen, France

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Dominique Vaur Departments of Biopathology, Centre François Baclesse, Caen, France

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Jean-Pierre Rame Departments of Head and Neck Surgery, Centre François Baclesse, Caen, France

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Stéphane Bardet Departments of Nuclear Medicine and Thyroid Unit, Centre François Baclesse, Caen, France

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Introduction Fine needle aspiration (FNA) cytology of thyroid nodules is considered as the key tool to distinguish between benign and malignant tumors [ 1 ]. However, FNA cytology is classified as indeterminate in approximately 20–30% of

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Gilles Russ Thyroid and Endocrine Tumor Unit, Department of Nuclear Medicine, Pitié Salpêtrière Hospital, University Pierre et Marie Curie, Paris, France

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Sophie Leboulleux Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, University Paris-Sud, Villejuif, France

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Laurence Leenhardt Thyroid and Endocrine Tumor Unit, Department of Nuclear Medicine, Pitié Salpêtrière Hospital, University Pierre et Marie Curie, Paris, France

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Introduction Over the latest two decades the use of imaging procedures, especially ultrasonography (US) has been the culprit of an epidemic of thyroid incidentalomas [ 1 ]. Thus, the clinician is confronted with a situation that necessitates

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Peter N. Taylor Thyroid Research Group, Institute of Experimental and Molecular Medicine, School of Medicine, Cardiff University, Cardiff
London School of Hygiene and Tropical Medicine, London

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Bijay Vaidya Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter, UK

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, and currently a key debate amongst endocrinologists. Anti-thyroid drugs (ATDs) have been used since the 1940s, and are the preferred treatment during pregnancy. Radio-iodine is absolutely contraindicated [ 2 , 3 ], and thyroidectomy in pregnancy

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Toru Takano Rinku General Medical Center, Izumisano, Japan
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita, Japan
Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Japan

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Introduction Thyroid cancer in children is a rare disease found in only a few children in a million. Since the Great East Japan Earthquake and following the Fukushima Daiichi Nuclear Plant accident in 2011, many children in Fukushima, Japan

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Ralf Paschke
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Silvia Cantara
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Anna Crescenzi
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Barbara Jarzab
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Thomas J. Musholt
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Manuel Sobrinho Simoes
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Introduction/Background Fine-needle aspiration (FNA) has high sensitivity and specificity in distinguishing benign from malignant thyroid lesions [ 1 ]. However, in 2–16% of cases cytology is not diagnostic [ 2 ], i.e., the material is

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Mario Monaco Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Gennaro Chiappetta Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Concetta Aiello Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Antonella Federico Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Romina Sepe Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Daniela Russo Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Alfredo Fusco Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy
Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil

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Pierlorenzo Pallante Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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the CBX7 gene was drastically downregulated in thyroid carcinoma cell lines versus normal thyroid cells. Subsequently, we demonstrated that there is progressive reduction in CBX7 expression levels that was well related with the malignant grade of the

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Sze May Ng Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
Department of Paediatrics, Southport and Ormskirk NHS Trust, Ormskirk, United Kingdom

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Mark A. Turner Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

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Shivaram Avula Department of Radiology, Alder Hey Foundation Trust Hospital, Liverpool, United Kingdom

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Introduction Neonatal thyroid ultrasonography has an important role in assessing thyroid anatomy in newborns with thyroid dysfunction. Hypothyroxinaemia of prematurity is also commonly reported among infants born prematurely and this is

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Shigenobu Nagataki Nagasaki University, Nagasaki, Radiation Effects Research Foundation, Hiroshima, and Radiation Effects Association, Tokyo, Japan

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Introduction A special report, ‘The Fukushima Accident’, was delivered at the 35th Annual Meeting of the European Thyroid Association in Krakow on September 11, 2011, and this study is the follow-up of the special report. In view of the

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Alexis Lacout Centre d’Imagerie Médicale, Aurillac, France

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Emmanuel Chamorey Unité d’Epidémiologie et Biostatistiques (UEB), Centre Antoine Lacassagne, Nice, France

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Juliette Thariat Department of Radiation Oncology, Baclesse Cancer Research Institute, Caen, France

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Mostafa El Hajjam Department of Radiology, Centre Hospitalier Universitaire Ambroise Paré, APHP, Université de Versailles Saint-Quentin en Yvelines, Boulogne-Billancourt, France

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Carole Chevenet Laboratoire d’Anatomie et de Cytologie Pathologique du CHU Estaing, Clermont Ferrand, France

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Renaud Schiappa Unité d’Epidémiologie et de Biostatistiques (UEB), Département Recherche Clinique Innovation et Statistiques (DRIS), Centre Antoine Lacassagne, Nice, France

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Pierre Yves Marcy Polyclinique Les Fleurs, Service Imagerie Médicale, Ollioules, France

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Introduction Thyroid carcinomas account for 1–1.5% of all cancers and have a pronounced female predominance (sex ratio F/M: 6–7 cases/1). The incidence of thyroid cancers is around 7.5 in females and 2.1 in males per year per 100

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Ilaria Muller Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

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Carla Moran Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom

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Beatriz Lecumberri Department of Endocrinology and Nutrition, La Paz University Hospital, IdiPAZ, Autonomous University of Madrid, Madrid, Spain

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Brigitte Decallonne Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Neil Robertson Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom

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Joanne Jones Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom

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Colin M. Dayan Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

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Introduction Thyroid dysfunction (TD) is a common side effect of many treatments acting with different mechanisms, including but not limited to interferon alpha [ 1 ], interleukin-2 [ 2 ], thalidomide [ 3 ], amiodarone [ 4 ], radiation therapy

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