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Departments of Biopathology, Centre François Baclesse, Caen, France
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Introduction Fine needle aspiration (FNA) cytology of thyroid nodules is considered as the key tool to distinguish between benign and malignant tumors [ 1 ]. However, FNA cytology is classified as indeterminate in approximately 20–30% of
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Introduction Over the latest two decades the use of imaging procedures, especially ultrasonography (US) has been the culprit of an epidemic of thyroid incidentalomas [ 1 ]. Thus, the clinician is confronted with a situation that necessitates
London School of Hygiene and Tropical Medicine, London
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, and currently a key debate amongst endocrinologists. Anti-thyroid drugs (ATDs) have been used since the 1940s, and are the preferred treatment during pregnancy. Radio-iodine is absolutely contraindicated [ 2 , 3 ], and thyroidectomy in pregnancy
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita, Japan
Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Japan
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Introduction Thyroid cancer in children is a rare disease found in only a few children in a million. Since the Great East Japan Earthquake and following the Fukushima Daiichi Nuclear Plant accident in 2011, many children in Fukushima, Japan
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Introduction/Background Fine-needle aspiration (FNA) has high sensitivity and specificity in distinguishing benign from malignant thyroid lesions [ 1 ]. However, in 2–16% of cases cytology is not diagnostic [ 2 ], i.e., the material is
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Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil
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the CBX7 gene was drastically downregulated in thyroid carcinoma cell lines versus normal thyroid cells. Subsequently, we demonstrated that there is progressive reduction in CBX7 expression levels that was well related with the malignant grade of the
Department of Paediatrics, Southport and Ormskirk NHS Trust, Ormskirk, United Kingdom
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Introduction Neonatal thyroid ultrasonography has an important role in assessing thyroid anatomy in newborns with thyroid dysfunction. Hypothyroxinaemia of prematurity is also commonly reported among infants born prematurely and this is
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Introduction A special report, ‘The Fukushima Accident’, was delivered at the 35th Annual Meeting of the European Thyroid Association in Krakow on September 11, 2011, and this study is the follow-up of the special report. In view of the
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Introduction Thyroid carcinomas account for 1–1.5% of all cancers and have a pronounced female predominance (sex ratio F/M: 6–7 cases/1). The incidence of thyroid cancers is around 7.5 in females and 2.1 in males per year per 100
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Introduction Thyroid dysfunction (TD) is a common side effect of many treatments acting with different mechanisms, including but not limited to interferon alpha [ 1 ], interleukin-2 [ 2 ], thalidomide [ 3 ], amiodarone [ 4 ], radiation therapy