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Laura Agate Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Francesca Bianchi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Federica Brozzi Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Pierina Santini Unit of Endocrine and Oncological Nuclear Medicine Therapy, Diagnostic and Imaging Department, University of Pisa, Pisa, Italy

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Eleonora Molinaro Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Valeria Bottici Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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David Viola Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Loredana Lorusso Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Paolo Vitti Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Rossella Elisei Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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. 2008 Jun ; 37 ( 2 ): 457 – 80 . 10.1016/j.ecl.2008.02.007 18502337 0889-8529 5 Cherk MH , Kalff V , Yap KS , Bailey M , Topliss D , Kelly MJ . Incidence of radiation thyroiditis and thyroid remnant ablation success rates

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Nicholas S. Andresen Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Buatti Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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Hamed H. Tewfik Iowa City Cancer Treatment Center, Iowa City, Iowa, USA

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Nitin A. Pagedar Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, USA

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Carryn M. Anderson Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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John M. Watkins Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA

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not be indicated [ 7 , 8 ], and recent phase III trials have demonstrated equivalent rates of thyroid remnant ablation with 30 versus 100 mCi doses of RAI [ 9 , 10 ], practice patterns remain highly variable by individual practitioner [ 11 ]. The

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Nianting Ju Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Liying Hou Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Hongjun Song Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Zhongling Qiu Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yang Wang Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Zhenkui Sun Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Quanyong Luo Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Chentian Shen Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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international literature, including many guidelines ( 6 , 7 , 8 ), as the minimum level of TSH stimulation for radioiodine therapy including thyroid remnant ablation. However, there is no definite evidence yet that TSH level ≥ 30 mU/L is necessary for

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Furio Pacini Department of Internal Medicine, Endocrinology and Metabolism and Biochemistry, Section of Endocrinology and Metabolism, University of Siena, Siena, Italy

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thyrotropin-stimulated postoperative thyroid remnant ablation in differentiated thyroid cancer. J Clin Endocrinol Metab 2007;92:3542–3546. 10.1210/jc.2007-0225 17609306 5 Chianelli M, Todino V, Graziano FM, Panunzi C, Pace D, Guglielmi R, Signore A

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Fabián Pitoia Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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Erika Abelleira Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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Graciela Cross Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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study, rhTSH in preparation for thyroid remnant ablation in patients with T4 primary tumors achieved a rate of ablation success that was not inferior to the rate after THW [ 21 ]. In a previous publication, we showed that rhTSH stimulation was associated

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Furio Pacini Section of Endocrinology, University of Siena, Siena, Italy

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Dagmar Fuhrer Department of Endocrinology, Diabetes and Metabolism, West German Cancer Centre (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany

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Rossella Elisei Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Daria Handkiewicz-Junak Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

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Sophie Leboulleux Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Markus Luster Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany

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Martin Schlumberger Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Johannes W Smit Radboud University Medical Center, Nijmegen, Netherlands

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metastatic disease Activities of 1110 MBq are equally effective as higher activities for remnant ablation - If low-risk patients are referred for thyroid remnant ablation, activity of 1110 MBq should be considered as effective and safer than higher

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Germán A. Jimenez Londoño Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Ana Maria Garcia Vicente Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Julia Sastre Marcos Department of Endocrinology, Complejo Hospitalario de Toledo, Toledo, Spain

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Francisco Jose Pena Pardo Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Mariano Amo-Salas Department of Mathematics, University of Castilla-La Mancha, Ciudad Real, Spain

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Manuel Moreno Caballero Department of Nuclear Medicine, Hospital Universitario Infanta Cristina Badajoz, Badajoz, Spain

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Maria Prado Talavera Rubio  Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Beatriz Gonzalez Garcia Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Niletys Dafne Disotuar Ruiz Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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Angel Maria Soriano Castrejón Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

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differentiated thyroid cancer: a meta-analysis involving 3947 patients. J Clin Endocrinol Metab 2012; 97: 2754–2763. 28 Tamilia M, Al-Kahtani N, Rochon L, Hier MP, Payne RJ, Holcroft CA, et al: Serum thyroglobulin predicts thyroid remnant ablation failure

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Syed Ali Imran Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada

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Karen Chu Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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Murali Rajaraman Department of Radiation Oncology, Dalhousie University, Halifax, Nova Scotia, Canada

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Drew Rajaraman Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada

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Sunita Ghosh Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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Sarah De Brabandere Department of Diagnostic Imaging, Western University, London, Ontario, Canada

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Stephanie M. Kaiser Division of Endocrinology, Dalhousie University, Halifax, Nova Scotia, Canada

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Stan Van Uum Department of Medicine, Western University, London, Ontario, Canada

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.1054/bjoc.2001.2173 11747326 0007-0920 21 Rachinsky I , Rajaraman M , Leslie WD , Zahedi A , Jefford C , McGibbon A , et al. Regional Variation across Canadian Centers in Radioiodine Administration for Thyroid Remnant Ablation in

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Cléber P. Camacho Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Susan C. Lindsey Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Teresa S. Kasamatsu Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Alberto L. Machado Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicine and Health, São Paulo, Brazil

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João Roberto M. Martins Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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Rosa Paula M. Biscolla Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicine and Health, São Paulo, Brazil

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Magnus R. Dias da Silva Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo

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José Gilberto H. Vieira Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicine and Health, São Paulo, Brazil

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Rui M.B. Maciel Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo
Fleury Medicine and Health, São Paulo, Brazil

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15943636 34 Karam M, Gianoukakis A, Feustel PJ, Cheema A, Postal ES, Cooper JA: Influence of diagnostic and therapeutic doses on thyroid remnant ablation rates. Nucl Med Commun 2003;24:489-495. 10.1097/00006231-200305000-00002 12717064 35

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Rosália P. Padovani Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil
Department of Nuclear Medicine, Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil

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Rui M.B. Maciel Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil

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Teresa S. Kasamatsu Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil

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Beatriz C.G. Freitas Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil

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Marilia M.S. Marone Department of Nuclear Medicine, Irmandade Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil

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Cleber P. Camacho Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil

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Rosa Paula M. Biscolla Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Brazil

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]. Previous studies have attempted to demonstrate the benefits of RID by comparing the results of thyroid remnant ablation after RAI treatment in groups of patients who do and do not adhere to an RID [ 12 , 14 ]. However, considering that the efficacy of

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