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diagnosis of GD, serum samples were measured for thyroid-binding inhibitory immunoglobulins (TBII) with the Cobas e411 analyzer, Elecsys (Roche Diagnostics, Mannheim, Germany). For the dilution analysis, TBII concentrations were measured with 4 different
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): 76 – 94 . 10.1159/000362597 25114871 2235-0640 24 Abeillon-du Payrat J , Chikh K , Bossard N , Bretones P , Gaucherand P , Claris O , et al. Predictive value of maternal second-generation thyroid-binding inhibitory
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thyroid-binding inhibitory immunoglobulins (TBII; Cobas e411 analyzer; Roche Diagnostics, Mannheim, Germany) and an enlarged gland with a typical “thyroid storm pattern” on Doppler ultrasound. Dilutions of Forskolin, M22 MAb Bovine TSH, and Patient
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-Chazot F, Bournaud C: Predictive value of maternal second-generation thyroid-binding inhibitory immunoglobulin assay for neonatal autoimmune hyperthyroidism. Eur J Endocrinol 2014; 171: 451–460. 151 Cove DH, Johnston P: Fetal hyperthyroidism
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Department of Pediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
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(TSHRAb – also known as thyroid-binding inhibitory immunoglobulin or TBII – and anti-TPO, respectively) should also be measured ( 4 ). An elevated FT3 level is a more sensitive marker of overt hyperthyroidism than FT4. This biochemical evaluation will