Search for other papers by P. Beck-Peccoz in
Google Scholar
PubMed
Search for other papers by A. Lania in
Google Scholar
PubMed
Search for other papers by A. Beckers in
Google Scholar
PubMed
Search for other papers by K. Chatterjee in
Google Scholar
PubMed
Search for other papers by J.-L. Wemeau in
Google Scholar
PubMed
Introduction The syndrome of ‘inappropriate secretion of TSH' was the term coined originally [ 1 ] to indicate two forms of central hyperthyroidism, i.e. thyrotropin (TSH)-secreting pituitary adenomas (TSHomas) and resistance to thyroid
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Search for other papers by Till Ittermann in
Google Scholar
PubMed
Search for other papers by Roberto Lorbeer in
Google Scholar
PubMed
Search for other papers by Daniel Tiller in
Google Scholar
PubMed
Search for other papers by Ina Lehmphul in
Google Scholar
PubMed
Search for other papers by Alexander Kluttig in
Google Scholar
PubMed
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Search for other papers by Stephan B. Felix in
Google Scholar
PubMed
Search for other papers by Karl Werdan in
Google Scholar
PubMed
Search for other papers by Karin Halina Greiser in
Google Scholar
PubMed
Search for other papers by Josef Köhrle in
Google Scholar
PubMed
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Search for other papers by Henry Völzke in
Google Scholar
PubMed
DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany
Search for other papers by Marcus Dörr in
Google Scholar
PubMed
.01.044 24530962 24 Ittermann T, Dörr M, Völzke H, Tost F, Lehmphul I, Köhrle J, Jürgens C: High serum thyrotropin levels are associated with retinal arteriolar narrowing in the general population. Thyroid 2014;24:1473-1478. 10.1089/thy.2014.0190 25156414
Search for other papers by Simon H.S. Pearce in
Google Scholar
PubMed
Search for other papers by Mario Vaisman in
Google Scholar
PubMed
Search for other papers by Jean-Louis Wemeau in
Google Scholar
PubMed
.1300350 28 Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P, Wilson PW, Benjamin EJ, D’Agostino RB: Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249–1252. 10.1056/NEJM
Search for other papers by Rudolf Hoermann in
Google Scholar
PubMed
Search for other papers by John E.M. Midgley in
Google Scholar
PubMed
Search for other papers by Rolf Larisch in
Google Scholar
PubMed
Ruhr Center for Rare Diseases (CeSER), Ruhr University of Bochum and Witten/Herdecke University, Bochum, Germany
Search for other papers by Johannes W. Dietrich in
Google Scholar
PubMed
stimulation by the pituitary hormone thyrotropin (TSH) will the levels rise adequately to satisfy the needs of the body. To prevent overstimulation, the system is regulated tightly via multiple negative feedback loops that monitor hormone concentrations and
Search for other papers by Ladan Mehran in
Google Scholar
PubMed
Search for other papers by Atieh Amouzegar in
Google Scholar
PubMed
Search for other papers by Hengameh Abdi in
Google Scholar
PubMed
Search for other papers by Negar Delbari in
Google Scholar
PubMed
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Search for other papers by Elham Madreseh in
Google Scholar
PubMed
Search for other papers by Maryam Tohidi in
Google Scholar
PubMed
Search for other papers by Mohammad Ali Mansournia in
Google Scholar
PubMed
Search for other papers by Fereidoun Azizi in
Google Scholar
PubMed
risk of developing subclinical hypothyroidism among participants with MetS in comparison with their counterparts without MetS [ 12 ]. There are also reports on higher thyrotropin (TSH) values in patients with MetS compared with non-MetS subjects [ 1
Search for other papers by Linda M. Thienpont in
Google Scholar
PubMed
Search for other papers by Katleen Van Uytfanghe in
Google Scholar
PubMed
Search for other papers by Sofie Van Houcke in
Google Scholar
PubMed
Search for other papers by Barnali Das in
Google Scholar
PubMed
Search for other papers by James D. Faix in
Google Scholar
PubMed
Search for other papers by Finlay MacKenzie in
Google Scholar
PubMed
Search for other papers by Frank A. Quinn in
Google Scholar
PubMed
Search for other papers by Michael Rottmann in
Google Scholar
PubMed
Search for other papers by Annick Van den Bruel in
Google Scholar
PubMed
total and free thyroid hormones and thyrotropin (TSH) [ 12 , 13 , 14 ]. The committee was established in light of the prevalence of thyroid disease, the frequency of laboratory testing, and multiple reports on discrepant measurement results. For total
Search for other papers by Christian Trummer in
Google Scholar
PubMed
Search for other papers by Hannes Reiher in
Google Scholar
PubMed
Search for other papers by Verena Theiler-Schwetz in
Google Scholar
PubMed
Search for other papers by Marlene Pandis in
Google Scholar
PubMed
Search for other papers by Christian Gstettner in
Google Scholar
PubMed
Search for other papers by Peter Potzinger in
Google Scholar
PubMed
Search for other papers by Tilman Keck in
Google Scholar
PubMed
Search for other papers by Thomas R. Pieber in
Google Scholar
PubMed
Institute of Pathology, Medical University of Graz, Graz, Austria
Institute for Clinical Pathology, Johannes Kepler University, Linz, Austria
Search for other papers by Sigurd Lax in
Google Scholar
PubMed
Department of Neuropathology, Institute of Pathology, Medical University of Graz, Graz, Austria
Department of Pathology, Neuropathology and Molecular Pathology, Medical University of Innsbruck, Innsbruck, Austria
Search for other papers by Johannes Haybaeck in
Google Scholar
PubMed
Search for other papers by Vinzenz Stepan in
Google Scholar
PubMed
Search for other papers by Stefan Pilz in
Google Scholar
PubMed
What Is Known about This Topic? The differential diagnosis of secondary hyperthyroidism may lead to several challenges. Although very rare, ectopic thyrotropin-secreting neuroendocrine pituitary tumors (TSH-PitNETs) need to be
Search for other papers by Tanvir Rizvi in
Google Scholar
PubMed
Search for other papers by Patrice K. Rehm in
Google Scholar
PubMed
Recombinant human thyrotropin-α (Thyrogen®; Genzyme Corp., Cambridge, Mass., USA) is increasingly being utilized in the management of differentiated thyroid cancer following thyroidectomy. It offers the advantage of avoidance of thyroid hormone withdrawal
Royal Victoria Infirmary, Newcastle upon Tyne, UK
Search for other papers by Simon H.S. Pearce in
Google Scholar
PubMed
Search for other papers by Georg Brabant in
Google Scholar
PubMed
Search for other papers by Leonidas H. Duntas in
Google Scholar
PubMed
Search for other papers by Fabio Monzani in
Google Scholar
PubMed
Search for other papers by Robin P. Peeters in
Google Scholar
PubMed
Queen Elizabeth Hospital, Gateshead, UK
Search for other papers by Salman Razvi in
Google Scholar
PubMed
Search for other papers by Jean-Louis Wemeau in
Google Scholar
PubMed
through March 2013. For our Medline search, we entered in various combinations the terms thyrotropin (TSH), L -thyroxine, SCH, goitre, replacement therapy, CV risk, heart, dyslipidaemia, diabetes, obesity, mental health, quality of life, drugs. The
Search for other papers by Tanja Diana in
Google Scholar
PubMed
Search for other papers by Hans-Peter Holthoff in
Google Scholar
PubMed
Search for other papers by Julia Fassbender in
Google Scholar
PubMed
Search for other papers by Christian Wüster in
Google Scholar
PubMed
Search for other papers by Michael Kanitz in
Google Scholar
PubMed
Search for other papers by George J. Kahaly in
Google Scholar
PubMed
Search for other papers by Martin Ungerer in
Google Scholar
PubMed
-stimulating Ab (TSAb) that activate the TSHR [ 2 - 7 ] or as antagonist, blocking (TBAb) the activity of the natural ligand thyrotropin (TSH) [ 8 , 9 ]. TSAb is a sensitive, specific, and reproducible biomarker for GD; it reliably predicts the response to