Filter

Refine by date

—

Refine by collections

  • Print
  • Save

Search Results

You are looking at 1 - 10 of 318 items for :

  • "Thyroxine" x
Clear All
Lars C. Moeller Department of Endocrinology and Metabolism, University of Duisburg-Essen, Essen, Germany

Search for other papers by Lars C. Moeller in
Google Scholar
PubMed Close
,
Yaw Appiagyei-Dankah Medical University of South Carolina, Charleston, S.C., USA

Search for other papers by Yaw Appiagyei-Dankah in
Google Scholar
PubMed Close
,
Birgit Köhler Institut für Experimentelle Pädiatrische Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

Search for other papers by Birgit Köhler in
Google Scholar
PubMed Close
,
Heike Biebermann Institut für Experimentelle Pädiatrische Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

Search for other papers by Heike Biebermann in
Google Scholar
PubMed Close
,
Onno E. Janssen Department of Endocrinology and Metabolism, University of Duisburg-Essen, Essen, Germany

Search for other papers by Onno E. Janssen in
Google Scholar
PubMed Close
, and
Dagmar Führer Department of Endocrinology and Metabolism, University of Duisburg-Essen, Essen, Germany

Search for other papers by Dagmar Führer in
Google Scholar
PubMed Close

Introduction In serum, thyroid hormone (TH) is mainly bound to transport proteins. The major proportion of circulating TH, 75% of T 4 and 70% of T 3 is bound to thyroxine-binding globulin [TBG; HUGO Gene Nomenclature Committee approved name

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000381093
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Kevin Stroek Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Kevin Stroek in
Google Scholar
PubMed Close
,
Annemieke C. Heijboer Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands

Search for other papers by Annemieke C. Heijboer in
Google Scholar
PubMed Close
,
Marja van Veen-Sijne Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Marja van Veen-Sijne in
Google Scholar
PubMed Close
,
Annet M. Bosch Division of Metabolic Disorders, Department of Pediatrics, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Annet M. Bosch in
Google Scholar
PubMed Close
,
Catharina P.B. van der Ploeg Department of Child Health, Netherlands Organization for Applied Scientific Research TNO, Leiden, The Netherlands

Search for other papers by Catharina P.B. van der Ploeg in
Google Scholar
PubMed Close
,
Nitash Zwaveling-Soonawala Department of Paediatric Endocrinology, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Nitash Zwaveling-Soonawala in
Google Scholar
PubMed Close
,
Robert de Jonge Department of Clinical Chemistry, Amsterdam UMC, Vrije Universiteit & University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Robert de Jonge in
Google Scholar
PubMed Close
,
A.S. Paul van Trotsenburg Department of Paediatric Endocrinology, Emma Children’s Hospital, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by A.S. Paul van Trotsenburg in
Google Scholar
PubMed Close
, and
Anita Boelen Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Anita Boelen in
Google Scholar
PubMed Close

concentrations, and in order to detect CH-C, thyroxine-binding globulin (TBG) is measured in the lowest 5% of T4 concentrations enabling calculation of a modified T4/TBG ratio that serves as an indirect measure of free T4 (FT4). With this approach, low T4 values

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000513516
Volume/Issue:
Volume 10: Issue 3
Open access
Hiroyuki Iwaki Division of Endocrinology, Department of Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Japan

Search for other papers by Hiroyuki Iwaki in
Google Scholar
PubMed Close
,
Kenji Ohba Medical Education Center, Hamamatsu University School of Medicine, Hamamatsu, Japan

Search for other papers by Kenji Ohba in
Google Scholar
PubMed Close
,
Eisaku Okada Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

Search for other papers by Eisaku Okada in
Google Scholar
PubMed Close
,
Takeshi Murakoshi Obstetrics and Gynecology, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan

Search for other papers by Takeshi Murakoshi in
Google Scholar
PubMed Close
,
Yumiko Kashiwabara Division of Endocrinology, Department of Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Japan

Search for other papers by Yumiko Kashiwabara in
Google Scholar
PubMed Close
,
Chiga Hayashi Division of Endocrinology, Department of Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Japan

Search for other papers by Chiga Hayashi in
Google Scholar
PubMed Close
,
Akio Matsushita Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

Search for other papers by Akio Matsushita in
Google Scholar
PubMed Close
,
Shigekazu Sasaki Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

Search for other papers by Shigekazu Sasaki in
Google Scholar
PubMed Close
,
Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan

Search for other papers by Takafumi Suda in
Google Scholar
PubMed Close
,
Yutaka Oki Department of Metabolism and Endocrinology, Hamamatsu-Kita Hospital, Hamamatsu, Japan

Search for other papers by Yutaka Oki in
Google Scholar
PubMed Close
, and
Rieko Gemma Division of Endocrinology, Department of Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Japan

Search for other papers by Rieko Gemma in
Google Scholar
PubMed Close

dosage that ensures maternal serum free thyroxine (FT4) levels at or moderately above the upper limit of the reference range is reported to be appropriate for fetal euthyroid status [ 2 ]. This recommendation was incorporated into the 2017 American

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000509324
Volume/Issue:
Volume 10: Issue 5
Free access
Laura P.B. Elbers Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam
Departments of Vascular Medicine, University of Amsterdam, Amsterdam

Search for other papers by Laura P.B. Elbers in
Google Scholar
PubMed Close
,
Hjalmar A. Boon Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam

Search for other papers by Hjalmar A. Boon in
Google Scholar
PubMed Close
,
Maaike I. Moes Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam

Search for other papers by Maaike I. Moes in
Google Scholar
PubMed Close
,
Bregje van Zaane Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam
Departments of Vascular Medicine, University of Amsterdam, Amsterdam

Search for other papers by Bregje van Zaane in
Google Scholar
PubMed Close
,
Dees P.M. Brandjes Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam
Departments of Vascular Medicine, University of Amsterdam, Amsterdam

Search for other papers by Dees P.M. Brandjes in
Google Scholar
PubMed Close
,
Eric Fliers Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam

Search for other papers by Eric Fliers in
Google Scholar
PubMed Close
,
Harry R. Büller Departments of Vascular Medicine, University of Amsterdam, Amsterdam

Search for other papers by Harry R. Büller in
Google Scholar
PubMed Close
,
Suzanne Cannegieter Department of Clinical Epidemiology, Leiden University Medical Center
Einthoven Laboratory for Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

Search for other papers by Suzanne Cannegieter in
Google Scholar
PubMed Close
, and
Victor E.A. Gerdes Department of Internal Medicine, Medical Center Slotervaart, University of Amsterdam, Amsterdam
Departments of Vascular Medicine, University of Amsterdam, Amsterdam

Search for other papers by Victor E.A. Gerdes in
Google Scholar
PubMed Close

thromboembolism (VTE) or bleeding. Higher plasma levels of free thyroxine (FT 4 ) have been associated with an increased VTE risk [ 1 , 2 , 3 ]. Conversely, lower levels of FT 4 seem to be associated with a bleeding tendency [ 4 , 5 ]. An observational cohort

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000446431
Volume/Issue:
Volume 5: Issue 2
Open access
Ladan Mehran Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Ladan Mehran in
Google Scholar
PubMed Close
,
Atieh Amouzegar Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Atieh Amouzegar in
Google Scholar
PubMed Close
,
Hengameh Abdi Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Hengameh Abdi in
Google Scholar
PubMed Close
,
Negar Delbari Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Negar Delbari in
Google Scholar
PubMed Close
,
Elham Madreseh Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Search for other papers by Elham Madreseh in
Google Scholar
PubMed Close
,
Maryam Tohidi Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Maryam Tohidi in
Google Scholar
PubMed Close
,
Mohammad Ali Mansournia Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Search for other papers by Mohammad Ali Mansournia in
Google Scholar
PubMed Close
, and
Fereidoun Azizi Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Search for other papers by Fereidoun Azizi in
Google Scholar
PubMed Close

. 2009 Jan 25 ; 10 : 5 http://dx.doi.org/10.1186/1745-6215-10-5 . 17 Amouzegar A , Delshad H , Mehran L , Tohidi M , Khafaji F , Azizi F . Reference limit of thyrotropin (TSH) and free thyroxine (FT4) in thyroperoxidase positive

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1159/000512665
Volume/Issue:
Volume 10: Issue 5
Free access
Sangeetha Sirigiri Departments of Endocrinology, Tirupati, India

Search for other papers by Sangeetha Sirigiri in
Google Scholar
PubMed Close
,
Suresh Vaikkakara Departments of Endocrinology, Tirupati, India

Search for other papers by Suresh Vaikkakara in
Google Scholar
PubMed Close
,
Alok Sachan Departments of Endocrinology, Tirupati, India

Search for other papers by Alok Sachan in
Google Scholar
PubMed Close
,
P.V.L.N. Srinivasarao Departments of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

Search for other papers by P.V.L.N. Srinivasarao in
Google Scholar
PubMed Close
,
Sunil Epuri Departments of Endocrinology, Tirupati, India

Search for other papers by Sunil Epuri in
Google Scholar
PubMed Close
,
Sailaja Anantarapu Departments of Endocrinology, Tirupati, India

Search for other papers by Sailaja Anantarapu in
Google Scholar
PubMed Close
,
Arun Mukka Departments of Endocrinology, Tirupati, India

Search for other papers by Arun Mukka in
Google Scholar
PubMed Close
,
Srinivasa Rao Chokkapu Departments of Endocrinology, Tirupati, India

Search for other papers by Srinivasa Rao Chokkapu in
Google Scholar
PubMed Close
,
Ashok Venkatanarasu Departments of Endocrinology, Tirupati, India

Search for other papers by Ashok Venkatanarasu in
Google Scholar
PubMed Close
, and
Ravi Poojari Departments of Endocrinology, Tirupati, India

Search for other papers by Ravi Poojari in
Google Scholar
PubMed Close

elevated low-density lipoproteins and triglycerides [ 5 ]. Adequate treatment with thyroxine (T 4 ) is reported to improve both the insulin resistance as well as the dyslipidemia [ 5 , 6 ]. Abnormal body composition in the form of an increase in the

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000448889
Volume/Issue:
Volume 5: Issue 4
Free access
Wilmar M. Wiersinga Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Wilmar M. Wiersinga in
Google Scholar
PubMed Close
,
Leonidas Duntas Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, Athens, Greece

Search for other papers by Leonidas Duntas in
Google Scholar
PubMed Close
,
Valentin Fadeyev Federal Endocrinological Scientific Center, Moscow, Russia

Search for other papers by Valentin Fadeyev in
Google Scholar
PubMed Close
,
Birte Nygaard Department of Endocrinology, Herlev Hospital, Herlev, Denmark

Search for other papers by Birte Nygaard in
Google Scholar
PubMed Close
, and
Mark P.J. Vanderpump Department of Endocrinology, Royal Free Hampstead NHS Trust, London, UK

Search for other papers by Mark P.J. Vanderpump in
Google Scholar
PubMed Close

thyroid hormones by the thyroid gland. Thyroxine (T4) is produced exclusively by the thyroid gland; its daily production rate is about 100 µg at an average body surface area of 1.79 m 2 (56.2 µg/day/m 2 ). Daily production rate of triiodothyronine (T3

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000339444
Volume/Issue:
Volume 1: Issue 2
Free access
P. Reed Larsen Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Harvard Institutes of Medicine, Boston, Mass., USA

Search for other papers by P. Reed Larsen in
Google Scholar
PubMed Close
and
Ann Marie Zavacki Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Harvard Institutes of Medicine, Boston, Mass., USA

Search for other papers by Ann Marie Zavacki in
Google Scholar
PubMed Close

Introduction When dietary iodine is sufficient, the major product of the thyroid gland is thyroxine (T4) which is secreted at a rate of 10-fold that of 3,5,3′-triiodothyronine (T3) in humans. Thus, a rate-limiting step in thyroid hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000343922
Volume/Issue:
Volume 1: Issue 4
Free access
Selwan Khamisi Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

Search for other papers by Selwan Khamisi in
Google Scholar
PubMed Close
,
Peter Lindgren Women's and Children's Health, University Hospital, Uppsala University, Uppsala, Sweden

Search for other papers by Peter Lindgren in
Google Scholar
PubMed Close
, and
F. Anders Karlsson Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

Search for other papers by F. Anders Karlsson in
Google Scholar
PubMed Close

/l (reference value 16.5 ± 5.3, mean ± SD [ 11 ]). Treatment with intra-amniotic injections of thyroxine was initiated and given in conjunction with ultrasound every 7-10 days with a dose 10 µg thyroxine/kg of estimated fetal weight per day on six occasions. The

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000357973
Volume/Issue:
Volume 3: Issue 1
Free access
Luca Persani Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

Search for other papers by Luca Persani in
Google Scholar
PubMed Close
,
Georg Brabant Experimental and Clinical Endocrinology Medical Clinic I – University of Lübeck, Lübeck, Germany

Search for other papers by Georg Brabant in
Google Scholar
PubMed Close
,
Mehul Dattani Genetics and Genomic Medicine Programme, UCL GOS Institute of Child Health, London, United Kingdom

Search for other papers by Mehul Dattani in
Google Scholar
PubMed Close
,
Marco Bonomi Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

Search for other papers by Marco Bonomi in
Google Scholar
PubMed Close
,
Ulla Feldt-Rasmussen Department of Medical Endocrinology and Metabolism, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

Search for other papers by Ulla Feldt-Rasmussen in
Google Scholar
PubMed Close
,
Eric Fliers Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by Eric Fliers in
Google Scholar
PubMed Close
,
Annette Gruters Department for Pediatric Endocrinology and Diabetes, Charité University Medicine, Berlin, Germany
University Hospital Heidelberg, Heidelberg, Germany

Search for other papers by Annette Gruters in
Google Scholar
PubMed Close
,
Dominique Maiter Department of Endocrinology and Nutrition, UCL Cliniques Saint-Luc, Brussels, Belgium

Search for other papers by Dominique Maiter in
Google Scholar
PubMed Close
,
Nadia Schoenmakers University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke’s Hospital and National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, United Kingdom

Search for other papers by Nadia Schoenmakers in
Google Scholar
PubMed Close
, and
A.S. Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Search for other papers by A.S. Paul van Trotsenburg in
Google Scholar
PubMed Close

onset of treatment causes irreversible neurological defects. More frequently, diagnosis is made biochemically and should be suspected in every individual with low circulating free thyroxine (FT4) concentrations (free thyroxine index, FTI, can be a

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000491388
Volume/Issue:
Volume 7: Issue 5
Free access