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from few published studies, no study has compared daily with weekly administration of LT4 in Indian hypothyroid patients. In view of these facts, the present study was planned to compare the effect of daily and weekly LT4 replacement on thyroid function
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her medication was explained. Treatment failure would call for supervised weekly administration of levothyroxine 1,000 μg. A beneficial evolution of fT 4 to 38.6 pmol/L was noted with a suppressed TSH using daily intake. It was even necessary to