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Rajesh Rajput Department of Endocrinology and Medicine Unit V, Pt. B.D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, India

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Vaibhav Pathak Department of Endocrinology and Medicine Unit V, Pt. B.D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, India

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from few published studies, no study has compared daily with weekly administration of LT4 in Indian hypothyroid patients. In view of these facts, the present study was planned to compare the effect of daily and weekly LT4 replacement on thyroid function

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Nancy Van Wilder Departments of Endocrinology, Vrije Universiteit Brussel, Brussels, Belgium

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Bert Bravenboer Departments of Endocrinology, Vrije Universiteit Brussel, Brussels, Belgium

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Sarah Herremans Departments of Psychiatry, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

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Nathalie Vanderbruggen Departments of Psychiatry, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium

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Brigitte Velkeniers Departments of Endocrinology, Vrije Universiteit Brussel, Brussels, Belgium

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her medication was explained. Treatment failure would call for supervised weekly administration of levothyroxine 1,000 μg. A beneficial evolution of fT 4 to 38.6 pmol/L was noted with a suppressed TSH using daily intake. It was even necessary to

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