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Introduction Anaplastic thyroid cancers (ATCs) are rare aggressive tumours, comprising only 1–2% of all thyroid cancers worldwide, and are typically associated with high mortality rates and a median overall survival (OS) of 5–12 months ( 1
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Center for Head and Neck Surgery, Kusatsu General Hospital, Kusatsu, Japan
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Introduction Anaplastic thyroid cancer (ATC) is one of the most aggressive cancers, and death usually occurs within a few months after diagnosis [ 1 ]. Surgery is the most effective treatment to improve the prognosis [ 2 - 4 ]; however, most
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Nova Medical School, Lisbon, Portugal
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Nova Medical School, Lisbon, Portugal
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Leite V . Anaplastic thyroid cancer: clinical picture of the last two decades at a single oncology referral centre and novel therapeutic options . Cancers 2019 11 1188. ( https://doi.org/10.3390/cancers11081188 ) 3 Chu YH Dias-Santagata D
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initially used for the treatment of malignant melanoma and then approved in other cancers, such as non-small cell lung cancer and clear cell renal cell carcinoma (ccRCC) [ 2 ]. More recently, a case of anaplastic thyroid cancer treated with vemurafenib and
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carcinoma. Cancer 1987; 60: 1428–1431. 5 Lowe NM, Loughran S, Slevin NJ, Yap BK: Anaplastic thyroid cancer: the addition of systemic chemotherapy to radiotherapy led to an observed improvement in survival – a single center experience and review of
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differential diagnosis based on FNA cytology results included schwannoma, melanoma, and medullary and anaplastic thyroid cancer. Immunohistochemistry was positive for S-100, suggesting a neural crest origin of the mass (Fig. 3 c) consistent with a schwannoma
University of Lille, Lille, France
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CRIStAL UMR CNRS 9189, University of Lille, Villeneuve-d’Ascq, France
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University of Lille, Lille, France
Institut National de la Santé et de la Recherche Médicale (INSERM), European Genomic Institute for Diabetes (EGID), CHU Lille, Lille, France
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University of Lille, Lille, France
Institut National de la Santé et de la Recherche Médicale (INSERM), European Genomic Institute for Diabetes (EGID), CHU Lille, Lille, France
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Department of Pathology, Lille University Hospital, Lille, France
University of Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277 - CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, Lille, France
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Deodato F Complete pathological response after chemo-radiation in anaplastic thyroid cancer: a report of two cases . Acta Oncologica 2016 55 530 – 532 . ( https://doi.org/10.3109/0284186X.2015.1102966 ) 16 Noguchi H Yamashita H Murakami T Hirai
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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NF1 mutations in anaplastic thyroid cancer . Endocrine . 2016 Dec 1 ; 54 ( 3 ): 733 – 41 . http://dx.doi.org/10.1007/s12020-016-1080-9 . 12 Subbiah V , Kreitman RJ , Wainberg ZA , Cho JY , Schellens JHM , Soria JC
Nuclear Medicine, Radiology Department, San Francisco VA Medical Center, San Francisco, Calif., USA
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untreated and in older patients, it can dedifferentiate into more aggressive and less treatable anaplastic thyroid cancer. Rarely, differentiated papillary cancer metastasizes to the lungs and very rarely to the skeleton and brain. Likewise nonlocal lymph
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, anaplastic thyroid cancer or lymphoma of the thyroid were excluded. Patients were randomised to complete the four QoL questionnaires in one of the 24 possible orders and then answered questions about which questionnaire they preferred. The questionnaires