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hypothyroidism or occasionally secondary to iatrogenic factors (e.g. immune checkpoint inhibitors). Although antidepressant and antipsychotic medications have been reported to influence TH levels by a variety of mechanisms ( 4 ), to our knowledge there are no
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neurotransmission which play a key role in the pathogenesis of depression and are targets for current antidepressant therapies [ 8 , 9 , 10 , 11 , 12 , 13 ]. These studies have shown increased serotonin levels in the cerebral cortex of rats after T3 administration
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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), treatments including thyroid surgery, radioiodine, antidepressant medication (model 2), region of residence, and income (model 3), and finally, model 4 comprising all covariates of model 1 through 3 except income in the primary analyses with education as
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infertile females with positive thyroid antibodies, and nearly 20% would treat euthyroid patients with simple goitre that grew over time (never indicated versus. others; p = NS). Unrelated conditions (depression resistant to anti-depressant medications
Institute of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden
Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden
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Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden
Gothenburg Centre for Person Centred-Care (GPCC), Göteborg, Sweden
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previous psychiatric conditions in GD was investigated in a Danish registry study, where the risk of having been hospitalized with a psychiatric disease and treated with antidepressants or anxiolytics before the onset of GD was observed to be increased in
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potential substrate recognition sites affect thyroid hormone transport by monocarboxylate transporter 8. Endocrinology 2013;154:2553-2561. 10.1210/en.2012-2197 23592749 65 Roth S, Kinne A, Schweizer U: The tricyclic antidepressant desipramine
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for antidepressant drugs, mood stabilizers, and sleep deprivation . Biol Psychiatry . 2003 Nov ; 54 ( 10 ): 1049 – 59 . 10.1016/S0006-3223(03)00414-1 14625147 0006-3223 162 Broedel O , Eravci M , Fuxius S , Smolarz T , Jeitner
