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Jorge Alberto Tapia-Martínez Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México
Laboratorio 6, Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados-Instituto Politécnico Nacional, Delegación Tlalpan, Ciudad de México, México

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Margarita Franco-Colín Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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Vanessa Blas-Valdivia Laboratorio de Neurobiología, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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Edgar Cano-Europa Laboratorio de Metabolismo I, Departamento de Fisiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Colonia Unidad Profesional Adolfo López Mateos, Delegación Gustavo A. Madero, Ciudad de México, México

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with type 2 diabetes mellitus (T2D) development ( 7 ), but until now neither in rats nor in humans, this hypothesis has been proved. In humans, some meta-analyses reveal an association between hypothyroidism, obesity, and dyslipidemia; however, it is

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1530/ETJ-21-0050
Volume/Issue:
Volume 11: Issue 1
Open access
Dominik Spira Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Nikolaus Buchmann Department of Cardiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Marcus Dörr Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Marcello R P Markus Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany

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Matthias Nauck German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany

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Sabine Schipf Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Joachim Spranger Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Ilja Demuth Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Charité – Universitätsmedizin Berlin, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany

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Elisabeth Steinhagen-Thiessen Department of Endocrinology and Metabolism, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Henry Völzke German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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Till Ittermann Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

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with low thyroid function and prediabetes seem to be more likely to progress to type 2 diabetes compared to those with prediabetes and thyroid hormone levels in the reference range ( 6 ). The effects of subclinical hypo- or hyperthyroidism on glucose

Article Type:
Research Article
Collections:
Metabolic and cardiovascular effects of thyroid hormone
DOI:
https://doi.org/10.1530/ETJ-21-0063
Volume/Issue:
Volume 11: Issue 2
Open access
Georgiana Sitoris Endocrine Unit Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Flora Veltri Endocrine Unit Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Malika Ichiche Endocrine Unit Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Pierre Kleynen Endocrine Unit Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Jean-Philippe Praet Department of Internal Medicine, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Serge Rozenberg Department of Gynecology and Obstetrics, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Kris G Poppe Endocrine Unit Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Introduction Thyroid autoimmunity (TAI) and (subclinical) hypothyroidism (SCH) have been associated with adverse pregnancy outcomes, such as miscarriage, preterm birth, and gestational diabetes mellitus (GDM) ( 1 ). TAI and GDM have been

Article Type:
Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-21-0142
Volume/Issue:
Volume 11: Issue 2
Open access
Theodora Pappa Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital

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Maria Alevizaki Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital
Department of Endocrinology, Metabolism and Diabetes, Evgenideion Hospital, Athens University School of Medicine, Athens, Greece

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Introduction Metformin is well established as a first-line pharmacotherapy for the management of diabetes mellitus (DM). This biguanide is an insulin sensitizer mainly in the liver, but also in the muscle, that activates AMP-activated protein

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000346248
Volume/Issue:
Volume 2: Issue 1
Free access
John H. Lazarus Centre for Endocrine and Diabetes Sciences, Cardiff University, Cardiff, UK

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): Oxford Textbook of Endocrinology and Diabetes, ed 2. Oxford, Oxford University Press, 2011, pp 552–557. 24 Rotondi M, Cappelli C, Pirali B, Pirola I, Magri F, Fonte R, Castellano M, Rosei EA, Chiovato L: The effect of pregnancy on subsequent

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000336102
Volume/Issue:
Volume 1: Issue 1
Free access
Antonio C. Bianco Division of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine, Miami, Fla., USA

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Sabina Casula Division of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine, Miami, Fla., USA

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increased BMI [ 53 ], and subsequently with type 2 diabetes mellitus [ 54 ]. A recent case-control study with 1,057 type 2 diabetes patients and 516 non-diabetic subjects indicated that the frequencies of D 2 Ala92Ala homozygosity were 16.4% (n = 173

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000339447
Volume/Issue:
Volume 1: Issue 2
Free access
Peter Taylor Departments of Diabetes and Endocrinology, Royal United Hospital, Bath
Centre for Endocrine and Diabetes Sciences, Department of Medicine, Cardiff University School of Medicine, Cardiff, UK

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Sandip Bhatt Departments of Gastroenterology, Royal United Hospital, Bath

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Ravi Gouni Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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Jonathan Quinlan Departments of Gastroenterology, Royal United Hospital, Bath

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Tony Robinson Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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of Prof. Colin Dayan (Centre for Endocrine and Diabetes Science, Cardiff University School of Medicine, Cardiff, UK) and Prof. Tony Weetman (Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK). References 1

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000336071
Volume/Issue:
Volume 1: Issue 1
Free access
Marko Stojanović Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Sandra Pekić Faculty of Medicine, University of Belgrade
Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Mirjana Doknić Faculty of Medicine, University of Belgrade
Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Dragana Miljić Faculty of Medicine, University of Belgrade
Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Slavica Ćirić Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Aleksandar Diklić Faculty of Medicine, University of Belgrade
Endocrine Surgery Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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Svetislav Tatić Faculty of Medicine, University of Belgrade
Institute of Pathology, Clinical Center of Serbia, Belgrade, Serbia

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Miloje Joksimović Clinic for Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia

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Emilija Manojlović-Gačić Faculty of Medicine, University of Belgrade
Institute of Pathology, Clinical Center of Serbia, Belgrade, Serbia

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Milica Skender-Gazibara Faculty of Medicine, University of Belgrade
Institute of Pathology, Clinical Center of Serbia, Belgrade, Serbia

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Vera Popović Faculty of Medicine, University of Belgrade
Neuroendocrine Department, Diabetes and Metabolic Diseases, Clinical Center of Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia

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What Is Known about This Topic? • Sellar masses most commonly represent pituitary adenoma, and only rarely metastatic tumors, usually originating from breast or lung carcinoma. Accelerated growth of a sellar mass, rapid onset of diabetes

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000343910
Volume/Issue:
Volume 1: Issue 4
Free access
Dulani Kottahachchi Department of Endocrinology and Diabetes, The Alfred Hospital, Australia

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Duncan J. Topliss Department of Endocrinology and Diabetes, The Alfred Hospital, Australia
Department of Medicine, Monash University, Melbourne, VIC, Australia

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, Takahashi Y: The prevalence of IgG4-related hypophysitis in 170 consecutive patients with hypopituitarism and/or central diabetes insipidus and review of the literature. Eur J Endocrinol 2014;170:161-172. 10.1530/EJE-13-0642 24165017

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000452623
Volume/Issue:
Volume 5: Issue 4
Free access
João Sérgio Neves Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal

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Ricardo Fontes-Carvalho Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Department of Cardiology, Centro Hospitalar Gaia/Espinho, Vila Nova de Gaia, Portugal

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Marta Borges-Canha Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal

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Ana Rita Leite Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal

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Sandra Martins Department of Clinical Pathology, Centro Hospitalar Universitário de São João, Porto, Portugal
EPIUnit – Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal

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Ana Oliveira Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal

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João Tiago Guimarães Department of Clinical Pathology, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Biomedicine, Faculdade de Medicina da Universidade do Porto, Porto, Portugal
EPIUnit – Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal

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Davide Carvalho Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal

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Adelino Leite-Moreira Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal

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Ana Azevedo EPIUnit – Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal
Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina da Universidade do Porto, Porto, Portugal

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Introduction Cardiovascular disease is the leading cause of death worldwide. Traditional risk factors, including diabetes, dyslipidemia, and hypertension, contribute significantly to the development of cardiovascular disease [ 1 ]. Intensive

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000508407
Volume/Issue:
Volume 10: Issue 2
Free access