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Furio Pacini
Furio Pacini
Section of Endocrinology, University of Siena, Siena, Italy
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Dagmar Fuhrer
Dagmar Fuhrer
Department of Endocrinology, Diabetes and Metabolism, West German Cancer Centre (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Rossella Elisei
Rossella Elisei
Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Daria Handkiewicz-Junak
Daria Handkiewicz-Junak
Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
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Sophie Leboulleux
Sophie Leboulleux
Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France
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Markus Luster
Markus Luster
Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany
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Martin Schlumberger
Martin Schlumberger
Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France
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Johannes W Smit
Johannes W Smit
Radboud University Medical Center, Nijmegen, Netherlands
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Introduction Differentiated thyroid cancer (DTC) accounts for more than 90% of all thyroid cancers. Over the last decades, an increasing incidence of DTC, mainly due to cancers of papillary histology, has been reported in many countries in
Andries H Groen
Andries H Groen
Department of Surgical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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Deborah van Dijk
Deborah van Dijk
Department of Surgical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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Wim Sluiter
Wim Sluiter
Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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Thera P Links
Thera P Links
Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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Hendrik P Bijl
Hendrik P Bijl
Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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John T M Plukker
John T M Plukker
Department of Surgical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
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Introduction Patients with differentiated thyroid cancer (DTC) commonly have a good prognosis, with 10-year survival rates of 80–95% ( 1 ). In 10–20% of the patients, recurrences occur within 5 years after initial surgical treatment followed
Carla Gambale
Carla Gambale
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Alessandro Prete
Alessandro Prete
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Lea Contartese
Lea Contartese
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Liborio Torregrossa
Liborio Torregrossa
Department of Surgical, Medical, Molecular Pathology and Critical Area, Anatomic Pathology Section, University Hospital of Pisa, Pisa, Italy
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Francesca Bianchi
Francesca Bianchi
Department of Nuclear Medicine, University Hospital of Pisa, Pisa, Italy
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Eleonora Molinaro
Eleonora Molinaro
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Gabriele Materazzi
Gabriele Materazzi
Department of Surgical, Medical, Molecular Pathology and Critical Area, Unit of Endocrine Surgery, University Hospital of Pisa, Pisa, Italy
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Rossella Elisei
Rossella Elisei
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Antonio Matrone
Antonio Matrone
Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy
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Introduction The main objective of the initial treatment of differentiated thyroid cancer (DTC) is to cure the patients and to reduce the risk of persistent/recurrent disease ( 1 ). However, in several patients, persistence or recurrence of
Nianting Ju
Nianting Ju
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Liying Hou
Liying Hou
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Hongjun Song
Hongjun Song
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Zhongling Qiu
Zhongling Qiu
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Yang Wang
Yang Wang
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Zhenkui Sun
Zhenkui Sun
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Quanyong Luo
Quanyong Luo
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Chentian Shen
Chentian Shen
Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Introduction Thyroid cancer, accounting for 586,000 cases worldwide, was ranked in ninth place for incidence in 2020 ( 1 ). Differentiated thyroid cancer (DTC) accounts for more than 90% of all thyroid malignancies ( 2 ). DTC patients usually
Jaume Capdevila
Jaume Capdevila
Vall d’Hebron University Hospital, Vall d’Hebron Institute of Oncology (VHIO), IOB Quiron-Teknon, Barcelona, Spain
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Desiree’ Deandreis
Desiree’ Deandreis
Department of Medical Sciences, Nuclear Medicine Unit, University of Turin, AOU Città della Salute e della Scienza, Turin, Italy
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Cosimo Durante
Cosimo Durante
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Sophie Leboulleux
Sophie Leboulleux
Service of Endocrinology, Diabetology, University Hospital Geneve, Geneve, Switzerland
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Markus Luster
Markus Luster
Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany
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Romana Netea-Maier
Romana Netea-Maier
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, The Netherlands
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Kate Newbold
Kate Newbold
Royal Marsden Hospital, London, United Kingdom
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Susanne Singer
Susanne Singer
Institute of Medical Biostatistics Epidemiology and Informatics (IMBEI), University Medical Center of Johannes Gutenberg University, Mainz, Germany
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Gerasimos P Sykiotis
Gerasimos P Sykiotis
Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
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Beate Bartes
Beate Bartes
Association “Vivre sans Thyroïde”, Léguevin, France
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Kate Farnell
Kate Farnell
Butterfly Thyroid Cancer Trust, Rowlands Gill, Tyne & Wear, UK
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Laura Deborah Locati
Laura Deborah Locati
Medical Oncology Unit, IRCCS ICS Maugeri, Pavia, Italy
Department of Internal Medicine and Therapeutics, University of Pavia, Italy
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Department of Internal Medicine and Therapeutics, University of Pavia, Italy
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early tumors as well as to the overdiagnosis of clinically indolent tumors ( 1 , 2 ). Differentiated thyroid cancer (DTC) accounts for the vast majority of cases, of which papillary thyroid cancer is the most common subtype ( 3 ). Other forms of TC
Patrick W. Owens
Patrick W. Owens
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
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Terri P. McVeigh
Terri P. McVeigh
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
Cancer Genetics Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom
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Cancer Genetics Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom
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Eoin J. Fahey
Eoin J. Fahey
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
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Marcia Bell
Marcia Bell
Department of Endocrinology, Galway University Hospital, Galway, Ireland
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Denis S. Quill
Denis S. Quill
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
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Michael J. Kerin
Michael J. Kerin
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
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Aoife J. Lowery
Aoife J. Lowery
Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
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radioactive iodine remnant ablation is associated with very low rates of structural disease recurrence in properly selected patients with differentiated thyroid cancer. Clin Endocrinol (Oxf) 2011; 75: 112–119. 15 Nixon IJ, Ganly I, Patel SG, Palmer FL
Nicholas S. Andresen
Nicholas S. Andresen
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA
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John M. Buatti
John M. Buatti
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA
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Hamed H. Tewfik
Hamed H. Tewfik
Iowa City Cancer Treatment Center, Iowa City, Iowa, USA
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Nitin A. Pagedar
Nitin A. Pagedar
Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa, USA
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Carryn M. Anderson
Carryn M. Anderson
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA
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John M. Watkins
John M. Watkins
Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA
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Introduction Thyroid cancer is the most frequently occurring endocrine cancer, with an increasing incidence noted in the US over the past 15 years [ 1 ]. Papillary and follicular histologic subtypes, known as “differentiated thyroid cancers
Germán A. Jimenez Londoño
Germán A. Jimenez Londoño
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Ana Maria Garcia Vicente
Ana Maria Garcia Vicente
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Julia Sastre Marcos
Julia Sastre Marcos
Department of Endocrinology, Complejo Hospitalario de Toledo, Toledo, Spain
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Francisco Jose Pena Pardo
Francisco Jose Pena Pardo
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Mariano Amo-Salas
Mariano Amo-Salas
Department of Mathematics, University of Castilla-La Mancha, Ciudad Real, Spain
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Manuel Moreno Caballero
Manuel Moreno Caballero
Department of Nuclear Medicine, Hospital Universitario Infanta Cristina Badajoz, Badajoz, Spain
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Maria Prado Talavera Rubio
Maria Prado Talavera Rubio
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Beatriz Gonzalez Garcia
Beatriz Gonzalez Garcia
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Niletys Dafne Disotuar Ruiz
Niletys Dafne Disotuar Ruiz
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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Angel Maria Soriano Castrejón
Angel Maria Soriano Castrejón
Nuclear Medicine Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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low-risk differentiated thyroid cancer (LRDTC) and second, to assess the influence of clinical factors in the therapeutic response. Methods A longitudinal and multicentre study, including 5 hospitals, was performed in accordance with the
Constance Xhaard
Constance Xhaard
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Juan J. Lence-Anta
Juan J. Lence-Anta
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Yan Ren
Yan Ren
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Françoise Borson-Chazot
Françoise Borson-Chazot
Groupement Hospitalier Lyon-Est, Hospices Civils de Lyon, Fédération d'Endocrinologie, Bron
Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon
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Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon
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Geneviève Sassolas
Geneviève Sassolas
Rhône-Alpes Thyroid Cancer Registry, Cancer Research Center of Lyon (UMR INSERM 1052, CNRS 5286), RTH Laennec Faculty of Medicine, University of Lyon, Lyon
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Claire Schvartz
Claire Schvartz
Thyroid Cancer Registry of Champagne-Ardennes, Institut Jean Godinot, Reims
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Marc Colonna
Marc Colonna
Cancer Registry of Isère, Meylan
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Brigitte Lacour
Brigitte Lacour
Institut Gustave Roussy, Villejuif, France
French National Registry of Childhood Solid Tumours, CHU, Nancy
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French National Registry of Childhood Solid Tumours, CHU, Nancy
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Arlette Danzon
Arlette Danzon
Cancer Registry of Doubs, EA 3181, Université de Franche-Comté, Besançon
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Michel Velten
Michel Velten
Cancer Registry of Bas-Rhin, EA 3430, Faculty of Medicine, University of Strasbourg, Strasbourg
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Enora Clero
Enora Clero
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Stéphane Maillard
Stéphane Maillard
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Emilie Marrer
Emilie Marrer
Cancer Registry of Haut-Rhin, Mulhouse Hospital, Mulhouse
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Laurent Bailly
Laurent Bailly
Public Health Department, University Hospital Nice, Nice
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Eugènia Mariné Barjoan
Eugènia Mariné Barjoan
Public Health Department, University Hospital Nice, Nice
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Martin Schlumberger
Martin Schlumberger
Institut Gustave Roussy, Villejuif, France
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Jacques Orgiazzi
Jacques Orgiazzi
Department of Endocrinology, Hospices Civils de Lyon, Lyon, France
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Elisabeth Adjadj
Elisabeth Adjadj
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Université Paris-Saclay, Villejuif, France
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Université Paris-Saclay, Villejuif, France
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Celia M. Pereda
Celia M. Pereda
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Silvia Turcios
Silvia Turcios
National Institute of Endocrinology, Cuba
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Milagros Velasco
Milagros Velasco
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Mae Chappe
Mae Chappe
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Idalmis Infante
Idalmis Infante
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Marlene Bustillo
Marlene Bustillo
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Anabel García
Anabel García
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Sirced Salazar
Sirced Salazar
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Regla Rodriguez
Regla Rodriguez
Cuban Public Health Ministry, Havana, Cuba
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Mohamed Amine Benadjaoud
Mohamed Amine Benadjaoud
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Rosa M. Ortiz
Rosa M. Ortiz
National Institute of Oncology and Radiobiology (INOR), Havana, Cuba
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Carole Rubino
Carole Rubino
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Florent de Vathaire
Florent de Vathaire
U1018, Centre d'Epidémiologie et de Santé des Populations (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France
Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Institut Gustave Roussy, Villejuif, France
Université Paris-Saclay, Villejuif, France
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Introduction Over the last few decades, the differentiated thyroid cancer (DTC) incidence has grown rapidly in many countries [ 1 ]. The study of DTC risk factors is therefore of great importance to understand this observed increase in
Mathieu Spaas
Mathieu Spaas
Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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Brigitte Decallonne
Brigitte Decallonne
Department of Endocrinology and Internal Medicine, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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Annouschka Laenen
Annouschka Laenen
Leuven Biostatistics and Statistical Bioinformatics Centre, Leuven, Belgium
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Jaak Billen
Jaak Billen
Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium
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Sandra Nuyts
Sandra Nuyts
Department of Radiation Oncology, KU Leuven – University of Leuven, University Hospitals Leuven, Leuven, Belgium
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Introduction The vast majority (> 90%) of thyroid carcinomas are differentiated thyroid cancer (DTC), which includes papillary (PTC) and follicular cancer (FTC), characterized by an indolent course and low mortality [ 1 ]. Primary management
