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Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
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Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
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accompanied by non-negligible side effects. Moreover, not all RAI-refractory NMTC patients harbor established mutations that make them eligible for treatment with these inhibitors. Preclinical studies have demonstrated that the cardiac glycoside digoxin
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, Onogawa T, Tanemoto M, Mizutamari H, Okada M, Chaki T, Masuda S, Tokui T, Eto N, Abe M, Satoh F, Unno M, Hishinuma T, Inui K, Ito S, Goto J, Abe T: Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc
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patients with asthma. Anticoagulation with warfarin or direct oral anticoagulants should be considered in all patients with atrial fibrillation. If digoxin is used, increased doses are often needed in the thyrotoxic state [ 2 , 5 , 6 , 72
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significant sustained beta-adrenoceptor blockade and offering the potential for better compliance ( 52 ). In case of contradictions (e.g. asthma and chronic obstructive pulmonary disease), other agents can be used instead (calcium-channel blockers, digoxin