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Yoon Young Cho, Hye Won Jang, Ji Young Joung, Sun-Mi Park, Dae Joon Jeong, Sun Wook Kim, and Jae Hoon Chung

Introduction Childhood thyroid cancer is a rare malignancy, but its incidence has been gradually increasing according to several epidemiologic studies [ 1 , 2 ]. An increase in the incidence of childhood thyroid cancer (aged 0-14 years) was

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Rima Bėrontienė, Edita Jašinskienė, Rosita Kiudelienė, Gintaras Kuprionis, Jurgita Makštienė, Raminta Macaitytė, Dalia Marčiulionytė, Lina Poškienė, Agnė Šemetaitė, Vygantas Šidlauskas, Raimondas Valickas, Rimantas Žalinkevičius, and Rasa Verkauskienė

-90% in adults [ 5 ]. A decade after the Chernobyl accident in 1986, the incidence of TC in children had increased dramatically, especially in the most radiation-contaminated areas of Belarus, Ukraine and Russia [ 6 ]. The Chernobyl accident demonstrated

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Ladan Mehran, Atieh Amouzegar, Hengameh Abdi, Negar Delbari, Elham Madreseh, Maryam Tohidi, Mohammad Ali Mansournia, and Fereidoun Azizi

individuals with and without MetS as well as evaluating the incidence of TD and trend of thyroid hormones according to the MetS group, during a 10 year follow-up in an iodine sufficient population. Materials and Methods Study Design TTS is a

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Santiago Tofé, Iñaki Argüelles, Ana Forteza, Cristina Álvarez, Alessandra Repetto, Luis Masmiquel, Irene Rodríguez, Eladio Losada, Nuria Sukunza, María Cabrer, Mildred Sifontes, María del Mar del Barrio, Antonia Barceló, Álvaro Tofé, and Vicente Pereg

Introduction Thyroid cancer (TC) represents 3% of the global incidence of all cancers, with 586,000 new patients estimated in 2020 worldwide ( ). It is the most frequent endocrine cancer and its global incidence

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Jeppe Lerche la Cour, Line Tang Møllehave, Bjarke Røssner Medici, Christian Zinck Jensen, Anne Ahrendt Bjerregaard, and Birte Nygaard


High compared with low educational level increases the odds of starting levothyroxine (L-T4) with a normal thyroid-stimulating hormone – the mechanism is most likely patient request. The use of liothyronine (L-T3) and desiccated thyroid extract (DTE) is also speculated to be initiated at patients’ request. Therefore, the primary aim of this study was to evaluate if educational level influences treatment with L-T3 and DTE.

Material and methods

In this register-based cross-sectional study, we included all Danish citizens ≥30 years with redeemed prescription of L-T4, L-T3, or DTE during 2017–2020. We defined educational levels as short, medium, and long (<10 years, 10–12 years, and above 12 years, respectively). The association between educational level and treatment with LT3 or DTE vs only LT4 was analyzed in logistic regression models adjusted for age and sex.


We included 154,360 individuals using thyroid medication of whom 3829 were treated with L-T3 (2.48%) and 430 with DTE (0.28%). The usage was highest among women (3.15%) and the age group 40–49 (5.6%). Longer education compared with short increased the odds of being treated with DTE or L-T3 (medium education odds ratio (OR) 1.61 (95% CI 1.50–1.8) and long education OR 1.95 (95% CI 1.79–2.13)). Test for trend: OR: 1.37 (95% CI 1.31–1.42). Adjustment for other covariates did not affect the results substantially.


Persons with a longer compared to a shorter education are more often treated with either DTE or L-T3, and the usage of these drugs is limited to less than 3% of thyroid hormone users.

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Kanhaiyalal Agrawal, James Weaver, Fahim Ul-Hassan, Jean-Pierre Jeannon, Ricard Simo, Paul Carroll, Johnathan G. Hubbard, Ashish Chandra, and Hosahalli Krishnamurthy Mohan

of thyroid incidentalomas on 18 F-FDG PET varies from 0.2 to 10.1% in different studies [ 4 ]. This could well be related to variation in geographic area, number of patients studied and patient characteristics. The incidence of malignant neoplasm

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Brigitte Decallonne, Annick Van den Bruel, Gilles Macq, Nathalie Elaut, and Harlinde De Schutter

Introduction In Belgium, higher thyroid cancer incidence – most pronounced for microcancers (T1a) – is present in the Southern region, Wallonia, compared to the Northern region, Flanders. In a pioneer national population

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Carles Zafon, Juan Antonio Baena, Josep Castellví, Gabriel Obiols, Oscar Gonzalez, José Manuel Fort, Ramon Vilallonga, Enric Caubet, Manuel Armengol, and Jordi Mesa

Introduction Numerous studies have shown a worldwide increase in the incidence of thyroid cancer (TC) in recent years [ 1 ] due to the increased frequency of papillary thyroid carcinoma (PTC). The reason for this increase is not well

Open access

Diana Borges Duarte, Vânia Benido Silva, Guilherme Assunção, André Couto Carvalho, and Cláudia Freitas

Introduction Differentiated thyroid carcinoma (DTC) is the most common endocrine gland malignancy, most frequently diagnosed among women between the ages of 45 and 54 years ( 1 , 2 ). Despite the increasing incidence worldwide over the last

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Emilie Sonne-Holm and Christoffer Holst Hahn

asymptomatic and self-limiting but can also lead to hypocalcaemia with symptoms of paraesthesia and muscle spasms manifesting within the first 24 h after surgery [ 14 ]. The incidence of complication varying from 1 to 50% [ 3 , 10 , 14 - 16 ] is in part