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Joanna Bogusławska Centre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, Warsaw, Poland

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Marlena Godlewska Centre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, Warsaw, Poland

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Ewa Gajda Centre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, Warsaw, Poland

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Agnieszka Piekiełko-Witkowska Centre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, Warsaw, Poland

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microchimerism Fetal cells (including cytotoxic T cells) migrate to mother and trigger immune response. The role of non-coding RNA in AITD NcRNAs are defined as untranslated RNA molecules that regulate gene expression. ncRNAs are categorized

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Mohammad-Reza Mahmoudian-sani Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Department of Genetics and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

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Ameneh Mehri-Ghahfarrokhi Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

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Majid Asadi-Samani Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran

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Gholam-Reza Mobini Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

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, Lloyd RV: Non-coding RNAs in thyroid cancer. Endocr Pathol 2016;27: 12–20. 10.1007/s12022-016-9417-8 26847830 29 Wang X-Z, Hang Y-K, Liu J-B, Hou Y-Q, Wang N, Wang M-J: Over-expression of microRNA-375 inhibits papillary thyroid carcinoma cell

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Sule Canberk Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal

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Joana C. Ferreira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Luísa Pereira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Rui Batısta Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Andre F. Vieira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Manuel Sobrinho Simões Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
Department of Pathology and Oncology, Centro Hospitalar São João, Porto, Portugal

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Valdemar Máximo Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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). DICER1 is a member of the RNAse III family that plays a key role in the biogenesis involved in the processing of small non-coding RNAs (microRNAs), potentially affecting gene regulation at the post-transcriptional level. Since the first report in 2001

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Barbara A. Demeneix CNRS/UMR7221, Muséum National d’Histoire Naturelle/Université Paris-Sorbonne, Paris, France

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cellular plasticity at the gene regulation level and transgenerational, epigenetic heredity. Although many cellular factors are implicated (including polycomb proteins, non-coding RNAs, microRNAs, and the 3D chromatin architecture itself), succinctly, the

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Vincenza Leone Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Concetta Langella Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Francesco Esposito Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Marco De Martino Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Myriam Decaussin-Petrucci Department of Pathology, Lyon Sud Hospital Center, Hospices Civils de Lyon, Lyon, France

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Gennaro Chiappetta Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Naples, Italy

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Antonio Bianco Dipartimento di Sanità Pubblica, Università di Napoli Federico II, Naples, Italy

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Alfredo Fusco Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli ‘Federico II', Naples, Italy
Instituto Nacional de Cancer (INCA), Rio de Janeiro, Brazil

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, Slack FJ: Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008;9:219-230. 10.1038/nrm2347 18270516 10 Leone V, D'Angelo D, Ferraro A, Pallante P, Rubio I, Santoro M, Croce CM, Fusco A: A TSH-CREB1-microRNA loop is required for

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Rob Janssen Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands

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Alice Muller Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands

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Warner S. Simonides Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands

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-like gene 1 (RTL1), as well as the non-coding RNA sequences Gtl2 (MEG3), Rian (MEG8), MIRG, and numerous miRNAs [ 62 ]. Activation of the DLK1-DIO3 region is an aspect of increased pluripotency and proliferative activity in stem cells and various tumors [ 63

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Stefan Matei Constantinescu Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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Julien Hospel Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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Chantal Daumerie Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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Orsalia Alexopoulou Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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Dominique Maiter Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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Maria-Cristina Burlacu Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

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& Ghafouri-Fard S . Dysregulation of non-coding RNAs in autoimmune thyroid disease . Experimental and Molecular Pathology 2020 117 104527 . ( https://doi.org/10.1016/j.yexmp.2020.104527 ) 32 Masetti G & Ludgate M . Microbiome and Graves

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Jacopo Manso Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy
Department of Women’s and Children’s Health, Pediatric Endocrinology Unit, Padua University Hospital, Padua, Italy

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Simona Censi Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Cristina Clausi Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Ilaria Piva Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Yi Hang Zhu Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Alberto Mondin Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Maria Chiara Pedron Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Susi Barollo Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Loris Bertazza Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Giulia Midena Department of Molecular Medicine, University of Padua, Padua, Italy

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Raffaele Parrozzani Department of Ophthalmology, University of Padua, Padua, Italy

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Caterina Mian Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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small, single-stranded, non-coding RNAs that play a role in regulating biological processes by inhibiting gene expression at the post-transcriptional level. They have emerged as crucial modulators of immunity and cellular processes ( 12 ). Only a few

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