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Julia Ramalho Amalio da Silva Breder Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Paulo Alonso Garcia Alves Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Lucio Araújo Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Barbara Pires Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Priscila Valverde Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Daniel Alves Bulzico Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Andrade Accioly Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Rossana Corbo Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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thyroid tumors ( 13 , 14 , 15 ). Although less frequently mentioned, the expression of progesterone receptors (PR) in DTC has also been described ( 13 , 14 , 15 ). Vannuchi et al. observed a positive correlation of tumor size and PR positivity ( 14

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Giacomo Sturniolo Department of Human Pathology of the Adult and Developmental Age “G. Barresi”

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Carles Zafon Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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Mariacarla Moleti Department of Experimental Medicine, University of Messina, Messina, Italy

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Josep Castellví Department of Pathology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

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Francesco Vermiglio Department of Experimental Medicine, University of Messina, Messina, Italy

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Jordi Mesa Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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of our study was to determine the immunohistochemical expression of ER-α and progesterone receptor (PR) in a large series of PTC patients, and to correlate the above expressions with epidemiological and clinical features. Patients and Methods

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Marine Sitbon Pharmacy Department, Hospital Saint-Louis APHP, Paris, France

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Porhuoy Chou Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Seydou Bengaly Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Brigitte Poirot Department of Molecular Oncology, Saint-Louis Hospital (AP-HP), Université Paris Cité INSERM U 944, CNRS UMR 7212, Paris, France

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Marie Laloi-Michelin Department of Internal Medicine, Hospital Lariboisière APHP, Paris, France

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Laure Deville Pharmacy Department, Hospital Saint-Louis APHP, Paris, France

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Atanas Pachev Radiology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Ahouefa Kowo-Bille Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Clement Dumont Medical Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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Cécile N Chougnet Endocrine Oncology Department, Saint-Louis Hospital (AP-HP), Université Paris Cité, Paris, France

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2, pT2N0, estrogen and progesterone receptor-positive, Her2-positive, Ki67 20%) by surgery and adjuvant chemotherapy (epirubicin, cyclophosphamide, docetaxel, trastuzumab) and anastrozole (until February 2019). In April 2019, she presented with

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Ilaria Muller Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Lucy S. Kilburn Institute of Cancer Research – Clinical Trials & Statistics Unit (ICR-CTSU), London, United Kingdom

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Peter N. Taylor Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Peter J. Barrett-Lee Academic Breast Department, Velindre Cancer Centre, Cardiff, United Kingdom

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Judith M. Bliss Institute of Cancer Research – Clinical Trials & Statistics Unit (ICR-CTSU), London, United Kingdom

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Paul Ellis Guy’s Hospital and King’s College, London, United Kingdom

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Marian E. Ludgate Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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Colin M. Dayan Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, United Kingdom

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negative, negative HER2, ER, and progesterone receptor; WLE, wide local excision; 95% CI, 95% confidence interval. Fig. 3. Univariate analyses by autoantibodies to thyroid peroxidase (TPOAb) categorized into tertiles. Kaplan-Meier curves

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Estefanía Rinaldini Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina

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Fiorella Campo Verde Arboccó Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina

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Marcelo Ezquer Centro de Medicina Regenerativa, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile

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Carlos Gamarra-Luques Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina
Facultad de Ciencias Médicas, Instituto de Fisiología, Universidad Nacional de Cuyo, Mendoza, Argentina

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María Belén Hapon Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo, Mendoza, Argentina
Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Mendoza, Argentina

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, Kuhn C , Hofmann S , Bayer B , . The expression of thyroid hormone receptors (THR) is regulated by the progesterone receptor system in first trimester placental tissue and in BeWo cells in vitro . Eur J Obstet Gynecol Reprod Biol . 2015 Dec ; 195

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R. Burns UCD School of Medicine and Medical Science, University College Dublin

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C. O'Herlihy UCD School of Medicine and Medical Science, University College Dublin
National Maternity Hospital, Dublin, Ireland

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P.P.A. Smyth UCD School of Medicine and Medical Science, University College Dublin

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of estrogen, receptors in the developing human placenta. Horm Metab Res 1997;29:604-610. 10.1055/s-2007-979109 9497895 33 Shanker YG, Rao AJ: Progesterone receptor expression in the human placenta. Mol Hum Reprod 1999;5:481-486. 10.1093/molehr

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Sepehr Torabinejad Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy

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Caterina Miro Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy

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Biagio Barone Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Ciro Imbimbo Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Felice Crocetto Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Monica Dentice Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy
CEINGE – Biotecnologie Avanzate Scarl, Naples, Italy

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RGGTCA (R is a purine). Based on their mode of action, they can be subdivided into four different sub-categories: (i) Type I receptors, comprising the AR, the estrogen receptor (ER), and the progesterone receptor (PR), are anchored in the cytoplasm by

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