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Department of Nuclear Medicine, The First Hospital of Jilin University, Changchun, China
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Department of Nuclear Medicine & Minnan PET Center, The First Affiliated Hospital of Xiamen University, Xiamen, China
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Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
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into two clinical situations: TKI-naive patients with RR-DTC diagnosed after 131 I therapy (initial treatment group) and patients with RR-DTC who had failed to first-line sorafenib treatment (salvage treatment group). Patients with concurrent cancers
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-guided 125 I seed brachytherapy as salvage treatment. A literature search of PubMed shows that there is only one other study on the use of 125 I seed implantation for the treatment of recurrent PTC. In this previous study by Parker et al. [ 13 ], a patient
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WDTC.” Ease of salvage treatment is dependent on the site of recurrence, with patients presenting with multiple surgeries or distant metastases demonstrating significantly worse overall or disease-specific survival, or disease control [ 29 - 32 ]. In