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Hrvoje Jakovac Department of Physiology, Immunology and Pathophysiology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia

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Antun Ferenčić Department of Forensic Medicine and Criminalistics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia

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Christophe Stemberger Department of Pathology, Clinical Hospital Centre Rijeka, Rijeka, Croatia

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Bojana Mohar Vitezić Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia

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Dražen Cuculić Department of Forensic Medicine and Criminalistics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia

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Images in thyroidology Clinical and laboratory findings of subacute thyroiditis have been repeatedly reported as being associated with acute Sars-Cov-2 infection and post-COVID-19 syndrome ( 1 , 2 , 3 ). Exact mechanisms and

Article Type:
Case Report
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-22-0005
Volume/Issue:
Volume 11: Issue 2
Open access
Saeed Sohrabpour Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Farrokh Heidari Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Ebrahim Karimi Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Reza Ansari Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Ardavan Tajdini Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Firouzeh Heidari Otorhinolaryngology Research Center, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

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manifestations have also been reported [ 4 - 6 ]. Whether coronavirus can directly attack the endocrine glands is unclear. Post-viral subacute thyroiditis (SAT, de Quervain thyroiditis) has been reported during outbreaks of other viral infection [ 7 , 8 ]. Here

Article Type:
Brief Report
DOI:
https://doi.org/10.1159/000511707
Volume/Issue:
Volume 9: Issue 6
Free access
Eijun Nishihara Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Nobuyuki Amino Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Takumi Kudo Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Kazuyoshi Kohsaka Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Shuji Fukata Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsushige Nishikawa Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Hirotoshi Nakamura Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Introduction Subacute thyroiditis, also referred to as granulomatous or De Quervain’s thyroiditis, is a spontaneously remitting, inflammatory disorder of the thyroid gland [ 1 - 3 ]. Patients usually present with tenderness and enlargement of

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000501033
Volume/Issue:
Volume 8: Issue 5
Open access
Akshay Khatri Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, New York, USA

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Esti Charlap Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Great Neck, New York, USA

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Angela Kim Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, New York, USA

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Established Facts Coronavirus disease 2019 is an ongoing pandemic that has many atypical presentations. Subacute thyroiditis can be triggered by multiple viral infections. Novel Insights Coronavirus disease 2019

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000511872
Volume/Issue:
Volume 9: Issue 6
Free access
Hayri Bostan Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Muhammed Erkam Sencar Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Murat Calapkulu Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Sema Hepsen Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Hakan Duger Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Ilknur Ozturk Unsal Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Mustafa Ozbek Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Erman Cakal Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey

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Introduction Subacute thyroiditis (SAT) is a self-limiting, inflammatory process of the thyroid gland that often presents with painful swelling of the thyroid. SAT affects females more often than males (female to male ratio of 4:1) [ 1 - 3

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000513745
Volume/Issue:
Volume 10: Issue 4
Free access
Sara De Vincentis Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy

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Simona Loiacono Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Eleonora Zanni Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Roberta Sueri Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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Maria Laura Monzani Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy

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Daniele Santi Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy

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Ilaria Muller Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Department of Endocrinology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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Francesco Di Marco School of Specialisation in Endocrinology, University of Milan, Milan, Italy

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Erica Crivicich School of Specialisation in Endocrinology, University of Milan, Milan, Italy

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Mirco Armenti School of Specialisation in Endocrinology, University of Milan, Milan, Italy

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Uberto Pagotto Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy

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Lorenzo Tucci Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy

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Carolina Cecchetti Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy

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Tommaso Trenti Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy

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Valentina Pecoraro Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy

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Giulia Canu Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy

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Manuela Simoni Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy

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Giulia Brigante Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy

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Graphical abstract Introduction Since the advent of the coronavirus disease (COVID-19) pandemic in early 2020 ( 1 ), a link between subacute thyroiditis (SAT) and severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection has

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-24-0083
Volume/Issue:
Volume 13: Issue 3
Open access
Bengt Hallengren Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Tereza Planck Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Peter Åsman Departments of Ophthalmology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Mikael Lantz Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Introduction Subacute thyroiditis (SAT) is, in most cases, a self-limiting, possibly viral, inflammatory disorder usually followed by a recovery of normal thyroid function [ 1 ]. The development of Graves' disease (GD) after

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000435915
Volume/Issue:
Volume 4: Issue 3
Free access
Hideyuki Imai H Imai, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Natsuko Watanabe N Watanabe, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Rei Hirose R Hirose, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Masakazu Koshibu M Koshibu, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Masahiro Ichikawa M Ichikawa, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Akiko Sankoda A Sankoda, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Shigenori Hiruma S Hiruma, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Nami Suzuki N Suzuki, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Masako Matsumoto M Matsumoto, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Miho Fukushita M Fukushita, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Ai Yoshihara A Yoshihara, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Jaeduk yoshimura Noh J yoshimura Noh, Department of Internal Medicine, Ito Hospital, Tokyo, Japan

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Kiminori Sugino K Sugino, Department of Surgery, Ito Hospital, Tokyo, Japan

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Koichi Ito K Ito, Department of Surgery, Ito Hospital, Tokyo, 150-8308, Japan

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Objective: There are few reports of subacute thyroiditis (SAT) during pregnancy. This study aimed to clarify the clinical characteristics of SAT in pregnant patients. Methods and results: Seven patients diagnosed with SAT during pregnancy at our institution from January 2004 to December 2021 were identified, and their clinical findings were retrospectively examined. At SAT diagnosis, the median age was 34 [range 31-42] years, the median duration of pregnancy was 5 [4-24] weeks, and all patients had neck pain but no fever. On laboratory examination, median (range) free thyroxine, free triiodothyronine, and C-reactive protein levels were 2.66 (1.14-7.77) ng/dL, 7.1 (3.3-16.1) pg/mL, and 2.22 (0.42-5.79) mg/dL, respectively, and all patients had a hypoechoic lesion of the thyroid gland. Three patients (43%) were treated with steroids, and 3 patients (43%) received replacement therapy with levothyroxine for hypothyroidism following destructive thyroiditis. There were no pregnancy complications in any of the cases. These 7 patients (pregnancy group) were compared with 217 non-pregnant female patients (non-pregnancy group) aged 31 to 42 years who were diagnosed with SAT at our institution from 2016 to 2019. The frequency of body temperatures above 37°C was lower in the pregnancy group than in the non-pregnancy group (0% vs. 65%). Conclusion: Patients who develop SAT during pregnancy may have less fever than non-pregnant patients with SAT. There were no pregnancy complications in the pregnancy group in this study. This suggests that adverse pregnancy outcomes may be avoided by appropriate management of SAT, including hypothyroidism after destructive thyroiditis.

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ETJ-24-0128
Volume/Issue:
Accepted Manuscripts
Open access
Georgios K. Markantes Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

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Marina A. Michalaki Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

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George A. Vagenakis Department of Pediatric Cardiology and Adult Congenital Heart Disease, Onassis Cardiac Surgery Center, Athens, Greece

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Fotini N. Lamari Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece

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Efthymia Pitsi Laboratory of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, University of Patras, Patras, Greece

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Maria Eliopoulou Endocrinology Unit, Karamandanio Hospital, Patras, Greece

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Nicholas G. Beratis Department of Pediatrics, University of Patras Medical School, Patras, Greece

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Kostas B. Markou Division of Endocrinology – Department of Internal Medicine, University of Patras Medical School, Patras, Greece

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): patients diagnosed with subacute thyroiditis, who had never used amiodarone. Group Control ( n = 21): euthyroid subjects, without history of thyroid disease or amiodarone use, with normal levels of thyroid function tests. Thyroid imaging was performed in

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000500355
Volume/Issue:
Volume 8: Issue 4
Free access
Naohiro Araki Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Mitsuru Iida Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Nobuyuki Amino Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Shinji Morita Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Akane Ide Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Eijun Nishihara Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Mitsuru Ito Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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Jun Saito Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan

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Tetsuo Nishikawa Department of Medicine, Yokohama Rosai Hospital, Yokohama, Japan

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Kiyonori Katsuragi Diagnostic Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan

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Akira Miyauchi Department of Internal Medicine, Kuma Hospital, Kobe, Japan

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; 37 female); 45 with thyrotoxic subacute thyroiditis (mean age 44 years, range 27-79 years; 42 female), 102 with chronic thyroiditis (52 euthyroid; mean age 53 years, range 15-79 years; 48 female); 50 with hypothyroidism (mean age 55 years, range 16

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000371740
Volume/Issue:
Volume 4: Issue 1
Open access