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Stan R Ursem Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands

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Anita Boelen Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development, Amsterdam, The Netherlands

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Jacquelien J Hillebrand Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands

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Wendy P J den Elzen Department of Laboratory Medicine, Laboratory Specialized Diagnostics & Research, Amsterdam UMC location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Public Health, Amsterdam, The Netherlands

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Annemieke C Heijboer Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Amsterdam Reproduction & Development, Amsterdam, The Netherlands
Department of Laboratory Medicine, Endocrine Laboratory, Amsterdam UMC Location Vrije Universiteit Amsterdam, Boelelaan, Amsterdam, The Netherlands

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Introduction Thyroid disorders are common. When a thyroid disorder is suspected, the standard procedure is measuring the serum or plasma thyroid-stimulating hormone (TSH). Accurate TSH measurements are important for timely diagnosis since

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James Magner Genzyme, a Sanofi company, Cambridge, Mass., USA

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Introduction Who discovered insulin? Penicillin? These questions have answers although they involve caveats and stories rather than one-word responses. So, who discovered thyroid-stimulating hormone (TSH)? In fact, the answer includes many

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Mahdi Kamoun Endocrinology and Metabolism Department

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Michèle d'Herbomez Department of Nuclear Medicine, Lille University Hospital, Lille

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Christine Lemaire Department of Endocrinology, Regional Hospital of Béthune, Béthune

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Armelle Fayard Endocrinology and Metabolism Department

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Rachel Desailloud Endocrinology and Metabolism Department, Amiens University Hospital, Amiens, France

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Damien Huglo Department of Nuclear Medicine, Lille University Hospital, Lille

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Jean-Louis Wemeau Endocrinology and Metabolism Department

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Introduction Thyroid-stimulating hormone (TSH)-secreting pituitary adenoma (TSHoma) is a rare tumor and represents less than 2% of all pituitary tumors [ 1 , 2 , 3 ]. The coexistence of autoimmune thyroid disease and TSHoma

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Enrique Soto-Pedre Division of Population Health & Genomics, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Moneeza K. Siddiqui Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Ify Mordi Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Cyrielle Maroteau Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Jimena Soto-Hernaez School of Medicine, University of Bristol, Bristol, United Kingdom

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Colin N.A. Palmer Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Ewan R. Pearson Division of Population Health & Genomics, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Graham P. Leese Division of Population Health & Genomics, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom
Department of Endocrinology and Diabetes, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom

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Introduction Genome-wide association studies (GWASs) have found association signals with serum thyroid-stimulating hormone (TSH) concentrations and/or hypothyroidism [ 1 - 4 ]. Replication studies in independent samples are scarce but

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Muhammed Erkam Sencar Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Davut Sakiz Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Murat Calapkulu Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Sema Hepsen Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Muhammed Kizilgul Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Ilknur Unsal Ozturk Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Bekir Ucan Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Murat Bayram Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Busra Betul Cagir Department of Internal Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Safak Akin Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Mustafa Ozbek Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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Erman Cakal Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

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that there may be potential different effects on the thyroid gland. To the best of our knowledge, there is no study in the literature evaluating the effect of exenatide treatment on thyroid gland volume and thyroid-stimulating hormone (TSH). The aim of

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Carolina Castro Porto Silva Janovsky Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Department of Medicine, Thyroid Outpatient Clinic, Division of Endocrinology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo, Brazil

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Fernando H. Cesena Hospital Israelita Albert Einstein, Sao Paulo, Brazil

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Viviane Arevalo Tabone Valente Hospital Israelita Albert Einstein, Sao Paulo, Brazil

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Raquel Dilguerian de Oliveira Conceição Hospital Israelita Albert Einstein, Sao Paulo, Brazil

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Raul D. Santos Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil

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Márcio Sommer Bittencourt Hospital Israelita Albert Einstein, Sao Paulo, Brazil
School of Medicine, Faculdade Israelita de Ciências da Saúde Albert Einstein, Sao Paulo, Brazil
Center for Clinical and Epidemiological Research, University Hospital, University of São Paulo School of Medicine, Sao Paulo, Brazil

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outcome using TSH as continuous and categorical variable Fig. 1. Prevalence of non-alcoholic fatty liver disease, according to thyroid-stimulating hormone quartiles (mUI/L). When further exploring the role of each individual

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Tilman Witte The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, N.H., USA
Institute for Community Medicine, Greifswald, Germany

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Henry Völzke Institute for Community Medicine, Greifswald, Germany

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Markus M. Lerch Departments of Medicine A, Greifswald, Germany

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Katrin Hegenscheid Departments of Diagnostic Radiology, Greifswald, Germany

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Nele Friedrich Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald School of Medicine, Greifswald, Germany

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Till Ittermann Institute for Community Medicine, Greifswald, Germany

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John A. Batsis The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, N.H., USA
Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, N.H., USA

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, Nagasawa SY, Morikawa Y, Ishizaki M, Kido T, Naruse Y, Nakashima M, Nogawa K, Suwazono Y, Nakagawa H: Association between a serum thyroid-stimulating hormone concentration within the normal range and indices of obesity in Japanese men and women. Intern Med

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R. Paschke Department of Endocrinology and Nephrology, Leipzig University, Leipzig, Germany

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M. Niedziela Department of Pediatric Endocrinology and Rheumatology, Poznan University of Medical Sciences, Poznan, Poland

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B. Vaidya Department of Endocrinology, Royal Devon and Exeter Hospital, Peninsula Medical School, Exeter, UK

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L. Persani Department of Clinical Sciences, and Community Health, University of Milan, and Istituto Auxologico Italiano, Milan, Italy

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B. Rapoport Autoimmune Disease Unit, Cedars-Sinai Research Institute and School of Medicine, University of California, Los Angeles, Calif., USA

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J. Leclere Centre Hospitalier Universitaire de Nancy, Nancy, France

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a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review. Endocr Pract 2008;14:479–483. 29 Bertalan R, Sallai A, Solyom J, Lotz G, Szabo I, Kovacs B, et al: Hyperthyroidism caused by a germline

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Bengt Hallengren Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Tereza Planck Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Peter Åsman Departments of Ophthalmology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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Mikael Lantz Departments of Endocrinology, Skåne University Hospital, Malmö
Department of Clinical Sciences, Lund University, Lund, Sweden

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SAT is very rare, and only a limited number of cases of GD occurring after SAT have been reported [ 2 , 3 , 4 , 5 , 6 ]. Here, we report a case of GD with opthalmopathy occurring 11 years after SAT with thyroid-stimulating hormone (TSH) receptor

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Fabián Pitoia Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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Erika Abelleira Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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Graciela Cross Division of Endocrinology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina

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administration of radioiodine for remnant ablation after recombinant human thyroid-stimulating hormone (rhTSH) therapy achieves results that are good and by no means inferior to the traditional way of preparing patients, i.e. by thyroid hormone withdrawal (THW

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