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Furio Pacini Section of Endocrinology, University of Siena, Siena, Italy

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Dagmar Fuhrer Department of Endocrinology, Diabetes and Metabolism, West German Cancer Centre (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany

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Rossella Elisei Section of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Daria Handkiewicz-Junak Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

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Sophie Leboulleux Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Markus Luster Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany

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Martin Schlumberger Gustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France

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Johannes W Smit Radboud University Medical Center, Nijmegen, Netherlands

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) adjuvant treatment or (c) treatment of known disease ( 9 ). In this context, remnant ablation refers to the use of RAI to destroy post-operatively remaining, presumably benign residual thyroid tissue to facilitate follow-up studies (such as serum

Article Type:
Other
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-21-0046
Volume/Issue:
Volume 11: Issue 1
Open access
Carla Colombo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Daniele Ceruti Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Simone De Leo Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy

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Grzegorz Bilo Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

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Matteo Trevisan Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Noemi Giancola Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Claudia Moneta Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Gianfranco Parati Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

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Luca Persani Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy

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Laura Fugazzola Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Introduction Multikinase inhibitors (MKIs) with strong anti-angiogenetic action are frequently used for the treatment of advanced radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) or medullary thyroid cancers (MTCs) ( 1 , 2

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0047
Volume/Issue:
Volume 12: Issue 4
Open access
Cosimo Durante Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Agnieszka Czarniecka M. Sklodowska-Curie National Research, Institute of Oncology Gliwice Branch, Gliwice, Poland

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Ralf Paschke Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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Gilles Russ Thyroid and Endocrine Tumors Department, Pitié-Salpêtrière Hospital, Sorbonne University GRC N°16, Paris, France

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Fernando Schmitt Faculty of Medicine of University of Porto, CINTESIS@RISE and Institute of Molecular Pathology and Immunology, University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Institute of Investigation and Innovation in Health (I3S), Faculty of Medicine of the University of Porto, Porto, Portugal

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Tamas Solymosi Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary

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Enrico Papini Department of Endocrine and Metabolic Diseases, Regina Apostolorum Hospital, Albano, Rome, Italy

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benign, asymptomatic, and do not warrant treatment. In the case of cancer diagnosis, most are small, intrathyroidal and indolent neoplasms (up to 53.6%, as shown in one contemporary large-scale study, in an unselected population) ( 3 ) that can safely be

Article Type:
Other
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Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0067
Volume/Issue:
Volume 12: Issue 5
Open access
Terry J. Smith Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, Ann Arbor, Michigan, USA
Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA

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consequences of targeted immune responses. These immune responses are thought to be intimately related to those occurring in the thyroid. Despite the potential seriousness of TAO, effective treatment of the disease represents an important, unmet need. This void

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000507992
Volume/Issue:
Volume 9: Issue 1_Suppl
Free access
María de los Ángeles Garayalde Gamboa Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Melina Saban Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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Marina Ines Curriá Service of Endocrinology, Metabolism, Nutrition, and Diabetes, Buenos Aires British Hospital, Buenos Aires, Argentina

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What Is Known about This Topic? True malabsorption is a cause of refractory hypothyroidism. Treatment with intramuscular levothyroxine (LT4) is an alternative for the treatment of these patients. What Does This Case Report Add

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000503324
Volume/Issue:
Volume 8: Issue 6
Free access
Hicham Benabdelkamel Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Malak A Jaber Pharmaceutical Medicinal Chemistry & Pharmacognosy, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan

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Lina A Dahabiyeh Division of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan

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Afshan Masood Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Reem H Almalki Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia

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Mohthash Musambil Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Anas M Abdel Rahman Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Medicine, College of Medicine and King Saud Medical City, King Saud University, Riyadh, Saudi Arabia

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Assim A Alfadda Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

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). Thyroid hormone replacement is currently the primary treatment method for hypothyroidism ( 6 ). According to patient feedback, levothyroxine (LT 4 ) is a synthetic replacement for thyroid tests. The recommended dose for adults is 1.6 µg/kg, adjusted every

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1530/ETJ-23-0062
Volume/Issue:
Volume 12: Issue 4
Open access
Luigi Bartalena Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy

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are in the end unhappy with the treatment outcome [ 2 ]. After medical treatment, many patients require some kind of rehabilitative surgery (orbital decompression, squint surgery, eyelid surgery) to correct residual manifestations. The reasons for this

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000356042
Volume/Issue:
Volume 2: Issue 4
Free access
Carla Gambale Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Alessandro Prete Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Lea Contartese Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Liborio Torregrossa Department of Surgical, Medical, Molecular Pathology and Critical Area, Anatomic Pathology Section, University Hospital of Pisa, Pisa, Italy

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Francesca Bianchi Department of Nuclear Medicine, University Hospital of Pisa, Pisa, Italy

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Eleonora Molinaro Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Gabriele Materazzi Department of Surgical, Medical, Molecular Pathology and Critical Area, Unit of Endocrine Surgery, University Hospital of Pisa, Pisa, Italy

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Rossella Elisei Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Antonio Matrone Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy

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Introduction The main objective of the initial treatment of differentiated thyroid cancer (DTC) is to cure the patients and to reduce the risk of persistent/recurrent disease ( 1 ). However, in several patients, persistence or recurrence of

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0052
Volume/Issue:
Volume 12: Issue 6
Open access
Sarah L. Lutterman Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Nitash Zwaveling-Soonawala Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Hein J. Verberne Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Frederik A. Verburg Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

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A.S. Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Christiaan F. Mooij Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Introduction In adults and children, hyperthyroidism is mostly caused by Graves’ disease (GD) [ 1 , 2 ]. Treatment options for GD include antithyroid drugs (ATDs), thyroidectomy, and radioactive iodine (RAI). In Europe, ATDs are the preferred

Article Type:
Systematic Review
DOI:
https://doi.org/10.1159/000517174
Volume/Issue:
Volume 10: Issue 5
Open access
Line Tang Møllehave Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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Allan Linneberg Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark

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Tea Skaaby Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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Nils Knudsen Department of Endocrinology, Bispebjerg University Hospital, University of Copenhagen, Copenhagen, Denmark

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Lars Ehlers Danish Center for Healthcare Improvements, Department of Business and Management, Aalborg University, Aalborg, Denmark

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Torben Jørgensen Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark
Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Faculty of Medicine, Aalborg University, Aalborg, Denmark

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Betina Heinsbæk Thuesen Research Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark

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Introduction Iodine fortification (IF) is implemented in more than 120 countries worldwide [ 1 ] to increase iodine intake, prevent thyroid diseases, and thus reduce treatment costs. The window of adequate iodine intake is narrow [ 2 ], hence

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000485973
Volume/Issue:
Volume 7: Issue 2
Free access