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Denise Zwanziger Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Helena Rakov Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Kathrin Engels Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Lars C. Moeller Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Dagmar Führer Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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of the bile duct [ 10 ]. Biliary diseases in humans can be associated with altered claudin-1 expression or mutations. For instance, in the neonatal ichthyosis-sclerosing cholangitis syndrome, claudin-1 gene mutations may lead to increased paracellular

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000431316
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Marta Di Stefano Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Carla Colombo Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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Simone De Leo Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Michela Perrino Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Mauro Viganò Division of Hepatology, San Giuseppe Hospital Multimedica IRCCS, Milan, Italy

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Luca Persani Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Clinical Sciences and Community Health, Milan, Italy

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Laura Fugazzola Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

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role in inducing their proliferation in response to cholestasis [ 19 ], drugs inhibiting VEGF-R are predicted to cause biliary diseases. The antiangiogenic activity of TKIs at the epithelium and muscularis layers of the gallbladder may also contribute

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000510369
Volume/Issue:
Volume 10: Issue 4
Free access
Renata Alencar Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil
Endocrinology Service, Department of Medicine, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil

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Daniel Barretto Kendler Endocrinology Service, Department of Medicine, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil

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Fernanda Andrade Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil

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Carla Nava Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil

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Daniel Bulzico Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil

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Cencita Cordeiro de Noronha Pessoa Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil

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Rossana Corbo Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil
Endocrinology Service, Department of Medicine, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil

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Fernanda Vaisman Endocrinology Service, Department of Medicine, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil
Endocrinology Service, Department of Medicine, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil

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cancer, biliary tract cancer, liver disease, gall bladder disease, inflammatory bowel disease, or any other malignant/benign disease in the digestive tract. Most patients underwent surgical treatment with total or partial thyroidectomy and were

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000497201
Volume/Issue:
Volume 8: Issue 4
Free access
Peter Taylor Departments of Diabetes and Endocrinology, Royal United Hospital, Bath
Centre for Endocrine and Diabetes Sciences, Department of Medicine, Cardiff University School of Medicine, Cardiff, UK

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Sandip Bhatt Departments of Gastroenterology, Royal United Hospital, Bath

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Ravi Gouni Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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Jonathan Quinlan Departments of Gastroenterology, Royal United Hospital, Bath

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Tony Robinson Departments of Diabetes and Endocrinology, Royal United Hospital, Bath

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are contraindicated. Case Report A 32-year-old with no clinical risk factors or evidence of pre-existing liver disease was diagnosed with Graves’ disease at week 4 in pregnancy. Her thyroid function tests revealed thyroid-stimulating hormone

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000336071
Volume/Issue:
Volume 1: Issue 1
Free access
Laura Ximena Kattah Martinez Pontificia Universidad Javeriana, Bogotá, Colombia

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Lisseth Fernanda Marín Carrillo Pontificia Universidad Javeriana, Bogotá, Colombia

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Leonardo Rojas Melo Pontificia Universidad Javeriana, Bogotá, Colombia

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the locally recurrent disease and metastatic and progressive lung involvement without iodine uptake. Therapy was initiated with 200 mg of oral sorafenib every 8 h. Three days after starting the medication, the patient consulted the emergency

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000488316
Volume/Issue:
Volume 7: Issue 3
Free access
Dagmar Führer Department of Endocrinology and Metabolism, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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Klaudia Brix Department of Life Sciences and Chemistry, Jacobs University Bremen, Bremen, Germany

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Heike Biebermann Institut für Experimentelle Pädiatrische Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany

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change in management recommendations, whereby persistent subclinical hyperthyroidism should now be treated in all patients above 65 years of age and treatment should also be considered in younger patients with known heart disease or risk for osteoporosis

Article Type:
Editorial
DOI:
https://doi.org/10.1159/000431318
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
Hicham Benabdelkamel Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Malak A Jaber Pharmaceutical Medicinal Chemistry & Pharmacognosy, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan

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Lina A Dahabiyeh Division of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan

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Afshan Masood Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Reem H Almalki Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia

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Mohthash Musambil Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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Anas M Abdel Rahman Metabolomics Section, Department of Clinical Genomics, Center for Genome Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Department of Medicine, College of Medicine and King Saud Medical City, King Saud University, Riyadh, Saudi Arabia

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Assim A Alfadda Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

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cardiovascular diseases. Therefore, novel approaches to managing hypothyroidism are urgently needed. Metabolomics is a well-known and widely utilized approach to understanding perturbation in an organ system under stress. This approach can provide novel

Article Type:
Research Article
Collections:
Hypothyroidism
DOI:
https://doi.org/10.1530/ETJ-23-0062
Volume/Issue:
Volume 12: Issue 4
Open access