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Tiziana de Filippis, Federica Marelli, Maria Cristina Vigone, Marianna Di Frenna, Giovanna Weber, and Luca Persani

normal gland, the antithyroid antibodies were negative and L -T 4 replacement therapy was started. The neurological evaluation revealed hypotonia and choreoathetosis. At 2 years of age neurological defects persisted and speech was modestly retarded