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  • Clinical Activity Score x
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Luigi Bartalena Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Wilmar M. Wiersinga Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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, edema of caruncle, conjunctival hyperemia, chemosis, could be considered, if based on comparison with a color picture atlas, as objective manifestations and, therefore, be included in the CRO. In other words, a new 5-item Clinical Activity Score (CAS

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000510700
Volume/Issue:
Volume 9: Issue 1_Suppl
Free access
Kenneth Ka Hei Lai Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

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Fatema Mohamed Ali Abdulla Aljufairi Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Department of Ophthalmology, Salmaniya Medical Complex, Government Hospitals, Bahrain

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Jake Uy Sebastian Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Department of Ophthalmology, Vicente Sotto Memorial Medical Center, Cebu City, Philippines

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Yingying Wei Department of Statistics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

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Ruofan Jia Department of Statistics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

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Karen Kar Wun Chan Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China

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Elaine Yuen Ling Au Division of Clinical Immunology, Department of Pathology, Queen Mary Hospital, Hong Kong Special Administrative Region, China

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Alan Chun Hong Lee Division of Endocrinology and Metabolism, Department of Medicine, Queen Mary Hospital, Hong Kong Special Administrative Region, China

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Chiu Ming Ng Department of Medicine, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China

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Hunter Kwok Lai Yuen Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China

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Wilson Wai Kuen Yip Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China

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Alvin Lerrmann Young Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China

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George Pak Man Cheng Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

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Clement Chee Yung Tham Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China

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Chi Pui Pang Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

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Kelvin Kam Lung Chong Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China

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followed up for at least 12 months. Outcome measures Clinical Activity Score (CAS) was used to assess the disease activity clinically ( 18 ). Gorman diplopia score was used to score diplopia: 1, no diplopia; 2, gaze-evoked diplopia; 3, intermittent

Article Type:
Research Article
Collections:
Thyroid function tests
DOI:
https://doi.org/10.1530/ETJ-23-0129
Volume/Issue:
Volume 13: Issue 4
Open access
Jacopo Manso Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy
Department of Women’s and Children’s Health, Pediatric Endocrinology Unit, Padua University Hospital, Padua, Italy

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Simona Censi Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Cristina Clausi Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Ilaria Piva Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Yi Hang Zhu Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Alberto Mondin Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Maria Chiara Pedron Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Susi Barollo Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Loris Bertazza Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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Giulia Midena Department of Molecular Medicine, University of Padua, Padua, Italy

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Raffaele Parrozzani Department of Ophthalmology, University of Padua, Padua, Italy

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Caterina Mian Department of Medicine (DIMED), Endocrinology Unit, University of Padua, Padua, Italy

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TED into mild, moderate-to-severe and sight-threatening. The most recent EUGOGO guidelines confirm the clinical activity score (CAS), proposed by Mourits et al. ( 9 ), as the best-validated scoring system for evaluating disease activity ( 7 ). TED is

Article Type:
Research Article
Collections:
Thyroid autoimmunity
DOI:
https://doi.org/10.1530/ETJ-23-0083
Volume/Issue:
Volume 12: Issue 5
Open access
Nora Dehina Institute for Experimental Endocrinology, Charité - Universitätsmedizin Berlin, Berlin
Department of Ophthalmology, University Hospital Essen, Essen, Germany

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Peter Josef Hofmann Institute for Experimental Endocrinology, Charité - Universitätsmedizin Berlin, Berlin

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Thomas Behrends Institute for Experimental Endocrinology, Charité - Universitätsmedizin Berlin, Berlin

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Anja Eckstein Department of Ophthalmology, University Hospital Essen, Essen, Germany

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Lutz Schomburg Institute for Experimental Endocrinology, Charité - Universitätsmedizin Berlin, Berlin

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-1860). The diagnosis of GO as well as the TRAK and IGF1R-aAB measurements have been described earlier [ 5 , 8 ]. The clinical activity score (CAS) and the severity of eye changes (NOSPECS) were determined according to previously published classification

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000442440
Volume/Issue:
Volume 5: Issue 1
Free access
Alice Nervo Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Alberto Ragni Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Alessandro Piovesan Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Valentina Marica Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Enrica Migliore Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Marco Gallo Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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Emanuela Arvat Oncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Città della Salute e della Scienza Hospital, Turin, Italy

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interference with daily activities of a symptomatic AE during treatment [ 10 ]. The EQ-5D-3L questionnaire assesses QoL through the EQ-5D descriptive system and the EQ visual analogue scale (EQ-VAS); a score (EQ-5D index) can be calculated combining these data

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000508186
Volume/Issue:
Volume 10: Issue 1
Free access
Murat Faik Erdoğan Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Özgür Demir Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Reyhan Ünlü Ersoy Department of Endocrinology and Metabolic Diseases, Yıldırım Beyazıt University Medical Faculty, Ankara, Turkey

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Kamile Gül Department of Endocrinology and Metabolic Diseases, Yıldırım Beyazıt University Medical Faculty, Ankara, Turkey

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Berna İmge Aydoğan Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Ziynet Alphan Üç Department of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey

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Türkan Mete Endocrinology and Metabolic Diseases, Ankara Numune Training and Research Hospital, Ankara, Turkey

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Sibel Ertek Department of Endocrinology and Metabolic Diseases, Ufuk University Medical Faculty, Ankara, Turkey

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Uğur Ünlütürk Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Bekir Çakır Department of Endocrinology and Metabolic Diseases, Yıldırım Beyazıt University Medical Faculty, Ankara, Turkey

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Yalçın Aral Department of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey

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Serdar Güler Endocrinology and Metabolic Diseases, Ankara Numune Training and Research Hospital, Ankara, Turkey

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Sevim Güllü Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Demet Çorapçıoğlu Department of Endocrinology and Metabolic Diseases, Ankara University Medical Faculty, Ankara, Turkey

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Selçuk Dağdelen Department of Endocrinology and Metabolic Diseases, Hacettepe University Medical Faculty, Ankara, Turkey

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Gürbüz Erdoğan Department of Endocrinology and Metabolic Diseases, Ufuk University Medical Faculty, Ankara, Turkey

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developed in the last 6 months 2 Thyroid volume ≥15 ml 3 No previous treatment except local interventions for GO 4 GO activity defined as clinical activity score (CAS) ≥3 and carrying at least one of the following criteria: proptosis ≥21 mm in one

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000444796
Volume/Issue:
Volume 5: Issue 2
Free access
Radu Mihai Department of Endocrine Surgery, Churchill Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

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surgery. In a study of 110 patients, the authors introduced a Swallowing Impairment Score (SIS) and found that SIS was significantly worse 1 week but not 1 month and 3 months after thyroidectomy ( 12 ). The aim of this study was to determine the

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0008
Volume/Issue:
Volume 12: Issue 4
Open access
Luba Freja Michaelsson Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark

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Jeppe Lerche  la Cour Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark

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Bjarke Borregaard Medici Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark

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Torquil Watt Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark

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Jens Faber Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Birte Nygaard Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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.03). With regards to the ER, there was a reduction, i.e., improvement, in tasks 2 and 3 ( p = 0.01 and p = 0.02). ThyPRO-39 composite scores did not correlate with changes in either MRT or ER. Table 4. Clinical parameters in hypothyroid patients

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000490383
Volume/Issue:
Volume 7: Issue 5
Free access
Claudio Marcocci Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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Marenza Leo Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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Maria Antonietta Altea Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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glucocorticoids (GC) was associated with a significant decrease of urinary 8-OHdG compared with pretreatment levels, which paralleled changes in the clinical activity score and ophthalmopathy index. The urinary 8-OHdG increased again in 2 patients who had a

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000337976
Volume/Issue:
Volume 1: Issue 2
Free access
Sofie Larsen Rasmussen Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen

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Lars Rejnmark Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Eva Ebbehøj Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen

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Åse Krogh Rasmussen Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen

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Jakob Bue Bjorner QualityMetric (an Optum Company), Lincoln, R.I., USA

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Torquil Watt Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen

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0.81. Table 1 Sociodemographic and clinical characteristics of the study populations Table 2 Differences in electronic and paper questionnaires There was no difference in score level between the two

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000443609
Volume/Issue:
Volume 5: Issue 1
Free access